DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXA and CG42514

DIOPT Version :9

Sequence 1:	NP_620475.2	Gene:	ACXA / 53432	FlyBaseID:	FBgn0040510	Length:	1112	Species:	Drosophila melanogaster
Sequence 2:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	340	Identity:	66/340 - (19%)
Similarity:	123/340 - (36%)	Gaps:	110/340 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   564 DLGIF--CVAF-------KDKSVEWNYLHQPDYIFKYSVALGWGIGCCLIY-IQSVNNSDIFYTG 618
            |:.||  |.|:       :.:::....|   |.|:..::.:|..:|..|.| :.:.:.:|:|
  Fly   193 DVAIFASCFAYISDISSLQQRTIRVTIL---DVIYLSAMPMGVALGSHLFYNVFNQSYADMF--- 251

  Fly   619 VVINIIAFFVLTFLLFICWYKKVCWWHSGQNEHRSYGKLSCAIF--HLFEKIQHSFVLRLTV--- 678
             .:| .:...|..:..:|..|    |.:...: ||..:|.|..|  ..|:|......|.:.|
  Fly   252 -TVN-ASLLALAIIYTLCALK----WQTTPRQ-RSLRELGCCGFWGDFFDKQHVKDSLAVLVKPR 309

  Fly   679 ------YMMIILCYYMVISLILMSCEKD--QYELDIIESKLYNYDMDPFTCFHPW---AYTNM-- 730
                  :::|:|     :|:.|.:.::|  ||        ||.|.:..|    .|   ||:|.
  Fly   310 KGHRRSFLIILL-----VSMALYTFQRDEGQY--------LYMYTLGKF----DWDVSAYSNFKT 357

  Fly   731 ---MALILGMSYTFARIPFALKTFIGCAEAVVFVLVVCFQYAFIFEHSVTTSPYLKAEIAHSCRV 792
               .|.::.|   ...:|...|........::|:.......|.:|.:..|.:..|.|    ...|
  Fly   358 FKSSAYVIAM---LLAVPLMNKILGWRDTTIIFIGTWAHSIARLFFYFATNTDLLYA----GAVV 415

  Fly   793 CM-------MLITMYAK-----ERQSEFNTKMNYKLNLDLQNKQKSADVTNQSIIILLNNILPSH 845
            |.       |:..|.:|     ||...|                        :::.:.:|.:|
  Fly   416 CSLGPIVGPMIRAMTSKIVPTSERGKVF------------------------ALLSVCDNAVP-- 454

  Fly   846 VVEVYLSSIAKHELY 860
                ::|.:...:||
  Fly   455 ----FISGVCYSQLY 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AC_N	<42..291	CDD:292831
		CYCc	262..464	CDD:214485
		Nucleotidyl_cyc_III	306..489	CDD:299850
		CYCc	831..1055	CDD:214485	5/30 (17%)
		Nucleotidyl_cyc_III	859..1080	CDD:299850	2/2 (100%)
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	63/331 (19%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	66/340 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4862
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.950