Protein Alignment ACXA and Phlpp1

DIOPT Version :9

• Sequence 1: NP_620475.2
• Gene: ACXA / 53432
• FlyBaseID: FBgn0040510
• Length: 1112
• Species: Drosophila melanogaster
• Sequence 2: XP_038946976.1
• Gene: Phlpp1 / 59265
• RGDID: 621308
• Length: 1718
• Species: Rattus norvegicus
• Alignment Length: 372
• Identity: 70/372 - (18%)
• Similarity: 134/372 - (36%)
• Gaps: 91/372 - (24%)

  Fly   212 IDFFHYLGFNMMGIFFRIMND---TMVRSSFLDRYQF---ITEEIWLRQARRQESLLLDSILPPQ 270
            ::..|.|.:  :|:.|....|   .:.:.:.:|:...   ..|.:.|:..||.          |.
  Rat   719 LENMHQLSY--LGLSFNEFTDIPEVLEKLTAVDKLCMAGNCMETLRLQALRRM----------PH 771

  Fly   271 IAK-PIQKSIKEKIIQPDNDF-YHLGTSRTAEN---FMSIQIHNDVSILYADLVNYTQLTTTLTV 330
            |.. .::.:|..|:|..:.|| .|:......:|   .:...|.|::.:|:.:   ..||.|....
  Rat   772 IKHVDLRLNILRKLITDEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLHCE---RNQLVTLNIC 833

  Fly   331 EKLVKVLH---DLYARFDLAALSFKVQRIKFLGDCYYCVAGLGESDPDHATMAVSLGISMIANIK 392
            ...:|.|:   :...:.|:..:...:..:....:|.       ||.|:....:..|      .:.
  Rat   834 GYFLKALYASSNELVQLDVYPVPNYLSYMDVSRNCL-------ESVPEWVCESRKL------EVL 885

  Fly   393 EVSVNRSLNIGMRIGVHSG--TLFAGVIGKAKLQYDIWGADVNIASRLEATG------------- 442
            ::..|:...:..|:..:|.  .|.||....|:|           ..|||.|.
  Rat   886 DIGHNQICELPARLFCNSSLRKLLAGHNRLARL-----------PERLERTSVEVLDVQHNQIIE 939

  Fly   443 SPGYVHVSGRTLSSLNAEEYNIY---PGTESAQKDPVLQKHPMSTYLLTAIPSLDSDKTISIVEG 504
            .|..:.:...:|..|||....:.   |.|.|.:...:||:..::...||       ||.:.::.|
  Rat   940 LPPNLLMKADSLRFLNASANKLETLPPATLSEETSSILQELYLTNNSLT-------DKCVPLLTG 997

  Fly   505 VPNLDLQTVGSNR-----KSQILKPNLLSHEMREEFRKMPVGGFKFQ 546
            .|.|.:..:..||     .|::.|        .||..::.:.|.|.:
  Rat   998 HPRLKILHMAYNRLQSFPASKMAK--------LEELEEIDISGNKLK 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AC_N	<42..291	CDD:292831	17/86 (20%)
		CYCc	262..464	CDD:214485	40/224 (18%)
		Nucleotidyl_cyc_III	306..489	CDD:299850	37/203 (18%)
		CYCc	831..1055	CDD:214485
		Nucleotidyl_cyc_III	859..1080	CDD:299850
Phlpp1	XP_038946976.1	Ubiquitin_like_fold	176..>224	CDD:421700
		PHA03247	<237..443	CDD:223021
		RA_PHLPP1	<424..491	CDD:340760
		PH_PHLPP-like	498..594	CDD:270131
		PLN00113	602..>1109	CDD:215061	70/372 (19%)
		leucine-rich repeat	604..624	CDD:275380
		leucine-rich repeat	625..655	CDD:275380
		leucine-rich repeat	679..701	CDD:275380
		leucine-rich repeat	702..724	CDD:275380	0/4 (0%)
		leucine-rich repeat	725..771	CDD:275380	9/57 (16%)
		leucine-rich repeat	772..795	CDD:275380	6/22 (27%)
		leucine-rich repeat	796..816	CDD:275380	2/19 (11%)
		leucine-rich repeat	817..858	CDD:275380	7/43 (16%)
		leucine-rich repeat	859..881	CDD:275380	4/28 (14%)
		leucine-rich repeat	882..904	CDD:275380	3/27 (11%)
		leucine-rich repeat	905..926	CDD:275380	8/31 (26%)
		leucine-rich repeat	927..950	CDD:275380	1/22 (5%)
		leucine-rich repeat	951..974	CDD:275380	7/22 (32%)
		leucine-rich repeat	977..1000	CDD:275380	7/29 (24%)
		leucine-rich repeat	1001..1024	CDD:275380	5/30 (17%)
		leucine-rich repeat	1067..1112	CDD:275380
		PP2Cc	1151..1403	CDD:214625

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900