Protein Alignment ACXA and Phlpp2

DIOPT Version :9

• Sequence 1: NP_620475.2
• Gene: ACXA / 53432
• FlyBaseID: FBgn0040510
• Length: 1112
• Species: Drosophila melanogaster
• Sequence 2: NP_001102601.2
• Gene: Phlpp2 / 498949
• RGDID: 1562857
• Length: 1359
• Species: Rattus norvegicus
• Alignment Length: 323
• Identity: 68/323 - (21%)
• Similarity: 126/323 - (39%)
• Gaps: 83/323 - (25%)

  Fly   270 QIAKPIQK-SIKEKIIQPDN--DFYHLG--TSRTAENFMSIQIHNDVSILYADLVNYTQLT---- 325
            ||.:.::| ::.:|::...|  :..:||  |.......:.:::::..:::..:|.....:|
  Rat   418 QIPEVLEKLTMLDKVVMAGNRLEILNLGVLTRMNHVKHVDLRMNHLKTVIIENLEGNKHITHMDL 482

  Fly   326 -----TTLTVEKLVKV-------------------LHDLYARFD-LAALSFKVQRIKFLGDCYYC 365
                 |.|.:..|..:                   |.:|||.:: |.|::  |..:..|......
  Rat   483 RDNQLTDLDLSSLCSLEQLHCERNQLRELTLSGFSLRNLYANWNKLTAVN--VYPVPSLLTSLEL 545

  Fly   366 VAGLGESDPDHATMAVSLGISMIANIKEVSVNRSLNIGMRIGVHSGTLFAGVIGK---------- 420
            ...|.|..||.|..|..|      .|.::|.|....:.||| :.|.:|...::|.
  Rat   546 SRNLLECIPDWACEAKKL------EILDISYNLLTEVPMRI-LSSLSLRKLMVGHNHIHVLPALV 603

  Fly   421 AKLQYDIWGADVNIASRLEAT-----GSPGYVHVSGRTLSSLNAEEYNIYPGTESAQKDPVLQKH 480
            ..:..::.....|..|||..|     .:..|::.|..:|.||.    :...|.||..   |||..
  Rat   604 EHIPLEVLDVQHNTLSRLPDTLFSKALNLRYLNASANSLESLP----SACAGEESLS---VLQLL 661

  Fly   481 PMSTYLLTAIPSLDSDKTISIVEGVPNL--------DLQTVGS---NRKSQILKPNLLSHEMR 532
            .::..|||       |:.|.::.|.|:|        .|||..:   |:..|:.:.||..::::
  Rat   662 YLTNNLLT-------DQCIPVLVGHPHLRVLHLANNQLQTFPASKLNKLEQLEELNLSGNKLK 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AC_N	<42..291	CDD:292831	5/23 (22%)
		CYCc	262..464	CDD:214485	47/242 (19%)
		Nucleotidyl_cyc_III	306..489	CDD:299850	47/226 (21%)
		CYCc	831..1055	CDD:214485
		Nucleotidyl_cyc_III	859..1080	CDD:299850
Phlpp2	NP_001102601.2	RA_PHLPP2	66..178	CDD:340761
		PH_PHLPP-like	185..279	CDD:270131
		PLN00113	284..>762	CDD:215061	68/323 (21%)
		leucine-rich repeat	289..309	CDD:275380
		leucine-rich repeat	310..336	CDD:275380
		leucine-rich repeat	337..359	CDD:275380
		leucine-rich repeat	360..382	CDD:275380
		leucine-rich repeat	383..405	CDD:275380
		leucine-rich repeat	406..428	CDD:275380	3/9 (33%)
		leucine-rich repeat	429..452	CDD:275380	5/22 (23%)
		leucine-rich repeat	453..476	CDD:275380	1/22 (5%)
		leucine-rich repeat	477..497	CDD:275380	4/19 (21%)
		leucine-rich repeat	498..517	CDD:275380	0/18 (0%)
		leucine-rich repeat	518..539	CDD:275380	7/22 (32%)
		leucine-rich repeat	540..562	CDD:275380	6/21 (29%)
		leucine-rich repeat	563..584	CDD:275380	7/27 (26%)
		leucine-rich repeat	586..607	CDD:275380	2/20 (10%)
		leucine-rich repeat	608..631	CDD:275380	5/22 (23%)
		leucine-rich repeat	632..681	CDD:275380	17/62 (27%)
		leucine-rich repeat	682..705	CDD:275380	5/22 (23%)
		leucine-rich repeat	706..728	CDD:275380	2/12 (17%)
		leucine-rich repeat	751..772	CDD:275380
		PP2Cc	820..1069	CDD:238083

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900