DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXA and Gucy1a1

DIOPT Version :9

Sequence 1:	NP_620475.2	Gene:	ACXA / 53432	FlyBaseID:	FBgn0040510	Length:	1112	Species:	Drosophila melanogaster
Sequence 2:	NP_058786.2	Gene:	Gucy1a1 / 497757	RGDID:	68436	Length:	690	Species:	Rattus norvegicus

Alignment Length:	202	Identity:	56/202 - (27%)
Similarity:	104/202 - (51%)	Gaps:	22/202 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   252 LRQARRQESLLLDSILPPQIAKPIQKSIKEKIIQPDNDFYHLGTSRTAENFMSIQIHNDVSILYA 316
            |.:.:::...||.||.|.::|:.:.:.   :|:|             |:.|      |:|::|::
  Rat   442 LEEEKKKTVDLLCSIFPSEVAQQLWQG---QIVQ-------------AKKF------NEVTMLFS 484

  Fly   317 DLVNYTQLTTTLTVEKLVKVLHDLYARFDLAALSFKVQRIKFLGDCYYCVAGLGESDPDHATMAV 381
            |:|.:|.:.:..:..:::.:|:.||.|||.......|.:::.:||.|....||......||....
  Rat   485 DIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHRESDTHAVQIA 549

  Fly   382 SLGISMIANIKEVSVNRSLNIGMRIGVHSGTLFAGVIGKAKLQYDIWGADVNIASRLEATGSPGY 446
            .:.:.|:....||.......|.||||:|||::||||:|....:|.::|.:|.:|::.|:...|..
  Rat   550 LMALKMMELSNEVMSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRK 614

  Fly   447 VHVSGRT 453
            ::||..|
  Rat   615 INVSPTT 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AC_N	<42..291	CDD:292831	9/38 (24%)
		CYCc	262..464	CDD:214485	55/192 (29%)
		Nucleotidyl_cyc_III	306..489	CDD:299850	45/148 (30%)
		CYCc	831..1055	CDD:214485
		Nucleotidyl_cyc_III	859..1080	CDD:299850
Gucy1a1	NP_058786.2	HNOB	<111..234	CDD:285002
		HNOBA	276..465	CDD:285003	7/22 (32%)
		CYCc	444..633	CDD:214485	55/200 (28%)
		Guanylate_cyc	471..642	CDD:278633	48/170 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810