DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXA and Gycalpha99B

DIOPT Version :9

Sequence 1:	NP_620475.2	Gene:	ACXA / 53432	FlyBaseID:	FBgn0040510	Length:	1112	Species:	Drosophila melanogaster
Sequence 2:	NP_477088.2	Gene:	Gycalpha99B / 43493	FlyBaseID:	FBgn0013972	Length:	676	Species:	Drosophila melanogaster

Alignment Length:	291	Identity:	79/291 - (27%)
Similarity:	140/291 - (48%)	Gaps:	49/291 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 VRSSFLDRYQFITEEIWLRQARRQESLLLDSILPPQIAKPIQKSIKEKIIQPDNDFYHLGTSRTA 299
            :::|..:....:|:|      |::...||..|.|.:||        ||:        .||:|..|
  Fly   417 IKNSIEEANSAVTKE------RKKNVSLLHLIFPAEIA--------EKL--------WLGSSIDA 459

  Fly   300 ENFMSIQIHNDVSILYADLVNYTQLTTTLTVEKLVKVLHDLYARFDLAALSFKVQRIKFLGDCYY 364
            :.:      .||:||::|:|.:|.:.:..|...::.:|..||..||.....|.|.:::.:||.|.
  Fly   460 KTY------PDVTILFSDIVGFTSICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYC 518

  Fly   365 CVAGLGESDPDHATMAVSLGISMIANIKEVSVNRSLNIGMRIGVHSGTLFAGVIGKAKLQYDIWG 429
            ..:||..:....|.....:.:.||....:...:....|.||||:|:||:.|||:|:...:|.::|
  Fly   519 VASGLHRASIYDAHKVAWMALKMIDACSKHITHDGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFG 583

  Fly   430 ADVNIASRLEATGSPGYVHVSGRT---LSSLNAEEYNIYPGTESAQKDP-VLQK---HPMST--- 484
            ..|.||::.|:......::||..|   |:.....|:.:.|      :|| .|.|   :|..|
  Fly   584 HSVTIANKFESGSEALKINVSPTTKDWLTKHEGFEFELQP------RDPSFLPKEFPNPGGTETC 642

  Fly   485 YLLTAI--PSLDSDKTISIVEGVPNLDLQTV 513
            |.|.:.  |:|||:  :.:||.: |:.::|:
  Fly   643 YFLESFRNPALDSE--LPLVEHI-NVSMKTI 670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AC_N	<42..291	CDD:292831	12/55 (22%)
		CYCc	262..464	CDD:214485	58/204 (28%)
		Nucleotidyl_cyc_III	306..489	CDD:299850	55/192 (29%)
		CYCc	831..1055	CDD:214485
		Nucleotidyl_cyc_III	859..1080	CDD:299850
Gycalpha99B	NP_477088.2	HNOB	76..208	CDD:285002
		HNOBA	259..451	CDD:285003	11/47 (23%)
		CYCc	430..619	CDD:214485	59/216 (27%)
		Guanylate_cyc	457..647	CDD:278633	56/201 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453981
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740