Protein Alignment ACXA and CG42637

DIOPT Version :9

• Sequence 1: NP_620475.2
• Gene: ACXA / 53432
• FlyBaseID: FBgn0040510
• Length: 1112
• Species: Drosophila melanogaster
• Sequence 2: NP_001007096.1
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Alignment Length: 1093
• Identity: 212/1093 - (19%)
• Similarity: 368/1093 - (33%)
• Gaps: 357/1093 - (32%)

  Fly   162 IYMFLP--------IPSSKAAALLAISVSLTYVIYFIHFMAFNEHNVAKYVHGLD-IVSIDFFHY 217
            ||:||.        :.|.:.|.|.|..   .|::.|:..|.::|....||:..:| |..:...|.
  Fly   226 IYVFLGAANSLVDFMSSMETAGLFARG---EYMVIFVDMMVYSEREAEKYLRRVDQITFMSNCHS 287

  Fly   218 L-GFNMMGIFFRIMNDTMVRSSFLDRYQFITEEIWLRQARRQESLLLDSILPP-----QIAKPIQ 276
            . .||.|.                                  .|||:.:..||     |..|.:|
  Fly   288 TENFNQMA----------------------------------RSLLVVASTPPTKDYIQFTKQVQ 318

  Fly   277 KSIKEKIIQPDN-DFYHLGTSRTAENFMSI------------------QIHNDVSILYADLV--- 319
            |...:   .|.| :...|........|:||                  .:..:..:|..|::
  Fly   319 KYSSK---PPFNLEIPRLFVESNFSKFISIYAAYLYDSVKLYAWAVDKMLREETRVLTDDVIFEV 380

  Fly   320 --NYTQLTTTLTVEKLV------KVLHDLY--ARFDLAALSFKVQRIKFLGD--CYYCVAGL--- 369
              |.|::..|:...:..      |:..|.|  :..:.:.|::|..:.....:  |.|.:..:
  Fly   381 ASNGTRVIDTIIKNRTYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNSNNMPCNYHMVPVAYF 445

  Fly   370 --GESDPDHATMAVSL---------------GISMIANIKEVSVNRSLNIGMRIGV---HSGTLF 414
              ||..|::..:..|:               |.:.....|:.:...|....:.:||   .||.:.
  Fly   446 HQGEEHPEYKLINGSIDWPSGGEKPADEPMCGFANELCKKDDTHYTSTVAAVVLGVLLFCSGVIT 510

  Fly   415 AGVIGKAKLQYDIWGADVNIASRLEATGSPGYVHVSGRTLSSLNAEEYNIYPGTESAQKDPVLQK 479
            ..:..|.|::.:|.|                       .|..::..|...|.|.|       :..
  Fly   511 MSIYRKWKIELEIEG-----------------------LLWKIDPNEIKGYSGNE-------IVS 545

  Fly   480 HPMSTYLLTAIPSLDSDKTISIVEGVPNLDLQTVGSNRKSQILKPNL--LSHEMREEFRKMPVGG 542
            .|....|::| .|..|..|...|.....|....|   |..::..|..  :|.|:.:|.|.:
  Fly   546 SPSKVSLMSA-QSYGSRWTNQFVTSTGRLRGAVV---RIKELKFPRKRDISREIMKEMRLL---- 602

  Fly   543 FKFQFPWSRRERNLKNEKVERDLGIFCVAFKDKSVE-WNYLHQPDYIFKYSVALGWGIGCCLIYI 606
                       |.|:::.:...:|        .||| ...|...||..|.|:       ..:|..
  Fly   603 -----------RELRHDNINSFIG--------ASVEPTRILLVTDYCAKGSL-------YDIIEN 641

  Fly   607 QSVNNSDIFYTGVVINIIAFFVLTFLLFICWYKKVCWWHSGQNEHRSYGKLSCAIFHLFEKIQHS 671
            :.:...|:|...::.::|              |.:.:.|:.|..:....|.|..:      :...
  Fly   642 EDIKLDDLFIASLIHDLI--------------KGMIYIHNSQLVYHGNLKSSNCV------VTSR 686

  Fly   672 FVLRLTVYMMIILCYYMVISLILMSCEKDQYELDIIESKLYNYDMDPFTCFHPW----------- 725
            ::|::|.:.:          ..|..|.:::   .|.|.:.|...:        |
  Fly   687 WMLQVTDFGL----------HELRQCAENE---SIGEHQHYRNQL--------WRAPELLRNHIH 730

  Fly   726 --------AYTNMMALILGMSYTFARIPFALKTFIGCAEAVVFVLVVCFQYAFIFEHSVTTSPYL 782
                    |:..:|..|......|.:|.|..|      |.|.:|..:..:....|...|.:  .:
  Fly   731 GSQKGDVYAFAIIMYEIFSRKGPFGQINFEPK------EIVDYVKKLPLKGEDPFRPEVES--II 787

  Fly   783 KAEIAHSC----RVCMMLITMYAKERQSEFNTKMN-----------------------YKLNLD- 819
            :||   ||    ..|:........|.:.||:...|                       |..||:
  Fly   788 EAE---SCPDYVLACIRDCWAEDPEERPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLED 849

  Fly   820 ---------LQNKQKSADVTNQSIIILLNNILPSHVVEVYLSSIAKHELYYENYRMVSVMFAMLT 875
                     .:.|.|:.|        ||:.:||..|.|..........:.|:   :|::.|:.:.
  Fly   850 IVTERTRLLCEEKMKTED--------LLHRMLPQSVAEKLTMGQGVEPVSYD---LVTIYFSDIV 903

  Fly   876 NF------QMDLPSLRVLNDIITAFDRLLSAYKQYYVVEKIKVVGCTYMAACGLDFSLIENLDSN 934
            .|      ...|..:..|||:.|.|||::..|..|    |::.:|..||...||..
  Fly   904 GFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVY----KVETIGDAYMVVSGLPI--------- 955

  Fly   935 SNFGSTSLSSELEQVRSRLESSIKEKNHDEVAFIMATFALDLMRVLSVCNKAYAGEPFDRALSTG 999
                                     ||.|..|..:|:.||:|:..:.....|:      |...|.
  Fly   956 -------------------------KNGDRHAGEIASMALELLHAVKQHRIAH------RPNETL 989

  Fly  1000 EIRIGISTGQIMAGVVGASQPHYDIWGNPVNMASRMESTGLSGHIQVTKETAQTLEEF--DVMCY 1062
            ::|||:.||.::|||||.:.|.|.::|:.||.||||||.|.:..|.::.:....|::.  ..:..
  Fly   990 KLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITE 1054

  Fly  1063 YRGLTFVKGRGEIPTYFVGIDKDLKFMSKKIDRLSENP-------SNPDLNHD 1108
            .|||..:||:|::.|:::....:.....|.:|.:...|       .:|.||.|
  Fly  1055 KRGLVNMKGKGDVVTWWLTGANENAIQKKLVDMMDMPPPLFSRPRKSPKLNPD 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AC_N	<42..291	CDD:292831	31/144 (22%)
		CYCc	262..464	CDD:214485	42/263 (16%)
		Nucleotidyl_cyc_III	306..489	CDD:299850	34/220 (15%)
		CYCc	831..1055	CDD:214485	60/229 (26%)
		Nucleotidyl_cyc_III	859..1080	CDD:299850	62/228 (27%)
CG42637	NP_001007096.1	PBP1_Speract_GC_like	26..445	CDD:107365	47/258 (18%)
		ANF_receptor	48..412	CDD:279440	43/225 (19%)
		PK_GC-A_B	543..827	CDD:270944	64/369 (17%)
		HNOBA	<835..881	CDD:285003	12/53 (23%)
		CYCc	860..1052	CDD:214485	64/246 (26%)
		Guanylate_cyc	887..1074	CDD:278633	62/233 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454002
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830