Protein Alignment ACXA and CG43373

DIOPT Version :10

• Sequence 1: NP_620475.2
• Gene: ACXA / 53432
• FlyBaseID: FBgn0040510
• Length: 1112
• Species: Drosophila melanogaster
• Sequence 2: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Alignment Length: 1165
• Identity: 301/1165 - (25%)
• Similarity: 509/1165 - (43%)
• Gaps: 283/1165 - (24%)

  Fly    53 LMISSLTVFVPMLILLIVALQVIIWSFTEYTKYIYINAIFDLGSLILVTGLLSINFFEDFVIRHR 117
            ||....:|.|.::::||..   |:::|                 |:.:....::|  |.|::
  Fly   517 LMQVDESVLVFLIVMLICG---IVYAF-----------------LLCILSKPAMN--EIFLV--- 556

  Fly   118 WVMTFTSTLSAYVVVLGDIAFNTYYYYKSNWPLNTLYD----VFVLCMIYMFLPIPSSKAAALLA 178
                    |.:||::...:|......|... |..:...    :.::.|.|..||: ..:.|.:..
  Fly   557 --------LVSYVILGTFLAIEVAVSYAMQ-PSKSFNGSACCIVLIYMTYTMLPL-RLREALIGG 611

  Fly   179 ISVSLTYVIYFIHFMAFNEHNVAKYVHGLDIVSIDFFHYLGFNMMGIFFRIMNDTMVRSSFLDRY 243
            |.:|:.::...:...|..:..| :.:|..::: ......|..|:.|::.....:...|.:|::..
  Fly   612 ILLSVVHLYTCLRLNAMQDEAV-EMIHWEELL-CTLVALLLANLTGVYTHWPKEKAQRKAFIETR 674

  Fly   244 QFITEEIWLRQARRQESLLLDSILPPQIAKPIQKSIKEKIIQPDNDFYHLGTSRTAENFMSIQIH 308
            |.|...:..::..:|:..||.|:||..:|..::..|..   ||.:..:|.         :.||.|
  Fly   675 QCIEARLRTQRENQQQERLLLSVLPRHVAMEMKDDIAG---QPRDTQFHK---------IYIQRH 727

  Fly   309 NDVSILYADLVNYTQLTTTLTVEKLVKVLHDLYARFDLAALSFKVQRIKFLGDCYYCVAGLGESD 373
            .:||||:||:..:|.|:...|.|:||::|::|:||||..|......|||.||||||||:||.|..
  Fly   728 ENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGDCYYCVSGLPEPR 792

  Fly   374 PDHATMAVSLGISMIANIKEVSVNRSLNIGMRIGVHSGTLFAGVIGKAKLQYDIWGADVNIASRL 438
            ||||..||.:|:.||..|..|....::|:.||:|:|:|.:..||:|..|.|:|:|..||.:|:.:
  Fly   793 PDHAHCAVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCGVLGLVKWQFDVWSNDVTLANHM 857

  Fly   439 EATGSPGYVHVSGRTLSSLNAEEYNIYPGTESAQKDPVLQKHPMSTYLLTAIPSLDSDKTISIVE 503
            |:.|.||.||::..||..|:. :|.:..| :..:::..|:.|.:.|||:
  Fly   858 ESGGIPGRVHITKETLKCLDG-DYEVEVG-KGNERNSYLKDHQIETYLI---------------- 904

  Fly   504 GVPNLDLQTVGSNRKSQILKPNLLSHEMR-------------------EEFRKMP---VGGFKFQ 546
             ||. |:.......::::.....:|.|:|                   .|..|.|   |..:..:
  Fly   905 -VPG-DIYRPHKKSRNRLQVNGNISKELRMMGHGTAQKHTSKFGFGDSSESAKDPEDEVNEYLMR 967

  Fly   547 FPWSRRERNLKNEKVERDLGIFCVAFKDKSVEWNYLHQPD-----YIF-KYSVALGWGIGCCLIY 605
            ...:|...:|:.|..:..|    :.|||..:|..|..:||     |.: ...|.||..| ..|:.
  Fly   968 AIDARSIDHLRAEHCQSLL----LCFKDNVLERKYASEPDRMLCVYFYCSLLVLLGTSI-MRLVV 1027

  Fly   606 IQSVNNSDIFYTGVVINIIAFFVLTFLLFICWYKKVCWW------------HSGQNEHRSYGKLS 658
            .||...:....||      |..:|.||:|:....|:.:.            ||.:...:.:...|
  Fly  1028 FQSSLLTLALSTG------ALLLLGFLVFLVACHKINFQLPSDIKRFSLRIHSNRRISQLFAFAS 1086

  Fly   659 CAIFHLFEKIQHSFVLRLTVYMMIILCYYMVISLILMSCEKDQYELDI----------IESKLYN 713
            .|:                :.:..:|..:......:...::.::.||:          :.:|:|:
  Fly  1087 VAL----------------IVLTTLLAMFQESGRQMELLQRRRFWLDVNGSISLNDTELNTKMYD 1135

  Fly   714 Y---DMDPFTCFHPWAYTNMMALILGMSYTFARIPFAL-------KTFIGCA------------- 755
            .   |.|.:..::.:....:::::...:|...||...|       .:::.|:
  Fly  1136 AEEPDCDFYLAYNTFLLLTLLSMMSCATYQVLRILLKLLLLLLASGSYMACSSNLYSRSREMSQE 1200

  Fly   756 ----EAVV-FVLVVCFQYAFIFEHSVTTSPYLKAEIAHSCRVCMMLITMYAKERQSEFNTKMNYK 815
                ||:: :::...|.:||:.           |.|.||                  ..|:..|:
  Fly  1201 LANEEALLRYIIDSIFLFAFML-----------ALIFHS------------------HQTEATYR 1236

  Fly   816 LNL--DLQNKQKSADVT-----NQSIIILLNNILPSHVVEVYLSSIAKH--ELYYENYRMVSVMF 871
            |:.  .||..::..|:.     |:.   ||.||||.||.|.:||. .||  :||:|....|.::|
  Fly  1237 LDFIWKLQATEEKEDMEHLQAYNRK---LLENILPVHVAEHFLSR-EKHLDDLYHEQCDSVCILF 1297

  Fly   872 AMLTNFQ---MDLPS-------LRVLNDIITAFDRLLSAYKQYYVVEKIKVVGCTYMAACGLDFS 926
            |.:.||.   ::|..       ||:||:||..||.|||. :::..:||||..|.|||||.||..:
  Fly  1298 ASIPNFSEFYVELEGNNEGVECLRLLNEIIADFDELLSE-ERFRCIEKIKSTGATYMAASGLTAN 1361

  Fly   927 LIENLDSNSNFGSTSLSSELEQVRSRLESSIKEKNHDEVAFIMATFALDLMRVLSVCNKAYAGEP 991
            ..:.:    ||...:                          .||.:||.|...:...|.
  Fly  1362 TCDRV----NFSHVT--------------------------AMADYALQLFDKIEEVNM------ 1390

  Fly   992 FDRALSTGEIRIGISTGQIMAGVVGASQPHYDIWGNPVNMASRMESTGLSGHIQVTKETAQTLE- 1055
              .:.:...:||||:.|.::|||:||.:|.||||||.||:||||:||||..|||||:|..|.||
  Fly  1391 --HSFNNFRMRIGINIGPVVAGVIGACKPQYDIWGNAVNVASRMDSTGLVDHIQVTQEMQQILEG 1453

  Fly  1056 -EFDVMCYYRGLTFVKGRGEIPTYFV----GID-KDLKFMSKKID-----RLSENPSNPD 1104
             .|::.|  ||...|||:|.:.|||:    .|| |:|:....:::     .|::.|...|
  Fly  1454 RGFELTC--RGSVDVKGKGSMITYFLKGRRPIDAKELELAKTEVEPPKTLTLAKEPEKLD 1511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AcyC	88..457	CDD:441717	109/372 (29%)
		Nucleotidyl_cyc_III	306..489	CDD:448371	78/182 (43%)
		Nucleotidyl_cyc_III	859..1080	CDD:448371	86/232 (37%)
CG43373	NP_001097622.2	AC_N	<523..720	CDD:318454	43/236 (18%)
		Guanylate_cyc	722..904	CDD:425528	78/183 (43%)
		Adcy_cons_dom	<949..1005	CDD:461877	15/59 (25%)
		Guanylate_cyc	1285..1479	CDD:425528	87/234 (37%)