Protein Alignment ACXA and CG10738

DIOPT Version :9

• Sequence 1: NP_620475.2
• Gene: ACXA / 53432
• FlyBaseID: FBgn0040510
• Length: 1112
• Species: Drosophila melanogaster
• Sequence 2: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Alignment Length: 1133
• Identity: 231/1133 - (20%)
• Similarity: 399/1133 - (35%)
• Gaps: 346/1133 - (30%)

  Fly   121 TFTSTLSAYVVVLGDI-AFNTYYY--YKSNWPLNTLYD-VFVLCMIYMFLPIPSSKAAALLAISV 181
            |..|||:...|.:.|| .:||.|:  :..| |...|.: .:....||:.|........  |.:|:
  Fly   201 TILSTLTDAGVSIRDIRTWNTIYHHGFMDN-PFEALVEQTYANTRIYLILGHYYEHVG--LMVSL 262

  Fly   182 SLTYVI----YFIHFMAFNEHNVA---KYVHGLDIVSID------FFHYLGF-----NMMGIFFR 228
            ....::    ||:..:...:::.|   ||:.||.:..::      |..|||.     .....|..
  Fly   263 QRRGILSKGDYFVVGIDIEQYDPAKPEKYLRGLLLEDVEPLAVQAFQSYLGIVPTASVSFATFAN 327

  Fly   229 IMNDTMVRSSF-----LDRY----QFITEEIWLRQARR--QESLL--LDSILPPQIAKPIQKSIK 280
            .:|..|.|..|     |..:    |...|..:|..|..  .::|:  |||...|:....|..:||
  Fly   328 EVNKYMERPPFNFPNPLGPFGGVKQISAEAAYLYDAVHLYAKALMEVLDSGGRPRNGSAIVAAIK 392

  Fly   281 EKIIQPDNDFYHLGTS-RTAENFMSIQIHNDVSILYADLV-NYTQLT----------TTLTVEKL 333
                         |:. |:|   |...::.|.:   .|.. |||.|.          |.|.:..:
  Fly   393 -------------GSRYRSA---MGYHVYIDEN---GDAAGNYTVLARGSVRNGRNQTVLGLRPV 438

  Fly   334 VKVLHDLYARFDLAALSFKVQRIKFLGDCYYCVAGLGESDPDHATMAVSLGISMIANIKEVSVNR 398
            ...:|   ....|:::|      |.|               .|..:.:...|..:...:..:..|
  Fly   439 GTFIH---RNSSLSSIS------KAL---------------PHQNLKLFSPIDWVGGTRPAAAPR 479

  Fly   399 SLNIGMRIGVHSGTLFAGVIGKAKL--------QYDIWGADVNIASRLEATGSPGYVHVSGRTLS 455
            ....|.:...::|.:.|.:.|.|.|        .|..|..:..:.|                .|.
  Fly   480 CGFGGEKCVNYTGEISAAIAGGALLLLSLVSLVLYRNWRYEQELDS----------------LLW 528

  Fly   456 SLNAEEYNIYPGTESAQKDPVLQKHPMSTYLLTAIP-SLDSDKTISIVEGVPNLDLQTVGSNRKS 519
            .::..|..|:......|.    ||  .:.:||..:| .|....|..::              |.|
  Fly   529 KIDFREVQIHENEREQQS----QK--QTRHLLNHLPRRLPPQSTHPLI--------------RTS 573

  Fly   520 QILKPNLLSHEMREEFRK----MPVGGFKFQFPWSRRERNLKNEKVERDLGIFCVAFKDKSVEWN 580
            |:    .||.....:||.    .|:|.:|.|....::.|. |:..:.|::.......:|.
  Fly   574 QV----SLSSNPDADFRYTTIFTPIGLYKGQLYAIKKVRK-KSVDITREMKKELKLLRDA----- 628

  Fly   581 YLHQPDYIFKYSVALGWGIGCC--------------------LIYIQSVNNSDIFYTGVVINIIA 625
               :.|.|..:       ||.|                    ::..:.|...::|...:|.:||
  Fly   629 ---RHDNICAF-------IGACTDPPNICIISEYCTRGSLKDILENEDVKLDNMFIASMVADII- 682

  Fly   626 FFVLTFLLFICWYKKVCWWHSGQNEHRSYGKL---SCAI----------FHLF----------EK 667
                         :.|.:.|  .:..|.:|.|   :|.:          |.||          ..
  Fly   683 -------------RGVIYLH--DSPIRFHGALCTSNCLVDSRWVVKLTDFGLFAFKQGIEDSSTD 732

  Fly   668 IQH--SFVLRLTVYMMIILCYYMVISLILMSCEKDQYELDIIESKLY-------NYDMDPFTC-- 721
            :||  :..|:| :|....|......||::.:...|.|...|:..:::       ...:.|..|
  Fly   733 MQHMSAKCLKL-LYRAPELLRQGPSSLVMGTQRGDAYSFGILLYEMHVRRGPFGETGLTPMQCLQ 796

  Fly   722 --FHPWAYTNMMALILGMSYTFARIPF-----ALKTFIGCAEAVVFVLVVCFQYAFI-------- 771
              ..|..|.|               |:     .|:|...|...       |.:..:.
  Fly   797 KVLQPQDYLN---------------PYRPSLQPLETAFDCVSE-------CLRECWAERPEDRPD 839

  Fly   772 FEHSVTTS--PYLKAEIAHSCRVCMMLITMYAKERQSEFNTKMNYKLNLDLQNKQKSADVTNQSI 834
            |: ::.|.  |..|....:.....|.::..||...::..:.:.:     .||.::|..|.
  Fly   840 FK-TIRTKLRPLRKGMRPNIFDNMMAMMEKYANNLEALVDDRTD-----QLQEEKKKTDA----- 893

  Fly   835 IILLNNILPSHVVEVYLSSIAK-HELYYENYRMVSVMFAMLTNF---QMDLPSLRV---LNDIIT 892
              ||:.:||..|.:    .:.| |::..|:|..||:.|:.:..|   ..:...|:|   |||:.|
  Fly   894 --LLHEMLPRCVAD----QLKKGHKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYT 952

  Fly   893 AFDRLLSAYKQYYVVEKIKVVGCTYMAACGLDFSLIENLDSNSNFGSTSLSSELEQVRSRLESSI 957
            .||.::..|..|    |::.:|..||...||..
  Fly   953 CFDSIIGHYDVY----KVETIGDAYMVVSGLPL-------------------------------- 981

  Fly   958 KEKNHDEVAFIMATFALDLMRVLSVCNKAYAGEPFDRALSTGEIRIGISTGQIMAGVVGASQPHY 1022
              :|.|..|..:||.:|.|:..:|.....:  .|.:|.|    :||||.:|.:.|||||...|.|
  Fly   982 --RNGDLHAAEIATMSLHLLSAVSEFKIRH--RPTNRLL----LRIGIHSGPVCAGVVGLKMPRY 1038

  Fly  1023 DIWGNPVNMASRMESTGLSGHIQVTKETAQTLEEFDVMCYY---RGLTFVKGRGEIPTYFVGIDK 1084
            .::|:.||.||||||:|:...|..:.:..|.|:...  .|:   ||:..:||:|:..||:: :.:
  Fly  1039 CLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLG--GYHFAERGVISMKGKGDQRTYWL-LGE 1100

  Fly  1085 DLKFMSKKIDRLSENPSNPDLNHDLDGS 1112
            |.:..:::....|:...:..||..:.|:
  Fly  1101 DEEARTRRTYERSQRRGSRALNKFIQGT 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AC_N	<42..291	CDD:292831	47/204 (23%)
		CYCc	262..464	CDD:214485	38/223 (17%)
		Nucleotidyl_cyc_III	306..489	CDD:299850	33/201 (16%)
		CYCc	831..1055	CDD:214485	64/230 (28%)
		Nucleotidyl_cyc_III	859..1080	CDD:299850	66/229 (29%)
CG10738	NP_729905.2	PBP1_Speract_GC_like	41..441	CDD:107365	59/261 (23%)
		ANF_receptor	67..416	CDD:279440	53/236 (22%)
		PK_GC-A_B	570..853	CDD:270944	58/356 (16%)
		TyrKc	597..847	CDD:197581	48/305 (16%)
		HNOBA	<862..907	CDD:285003	12/60 (20%)
		CYCc	886..1078	CDD:214485	68/248 (27%)
		Guanylate_cyc	913..1099	CDD:278633	66/232 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810