Protein Alignment ACXA and ACXD

DIOPT Version :9

• Sequence 1: NP_620475.2
• Gene: ACXA / 53432
• FlyBaseID: FBgn0040510
• Length: 1112
• Species: Drosophila melanogaster
• Sequence 2: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Alignment Length: 1169
• Identity: 452/1169 - (38%)
• Similarity: 660/1169 - (56%)
• Gaps: 130/1169 - (11%)

  Fly    24 NERLWEQSYLKARCKELHLEEEYMKYKIRLMISSLTVFVPMLILLIVALQVIIWSFTEYTKYIYI 88
            ||:.||.|||..:|:.|.||:.|..|..||.:..|::|: .:.:.:..:..::...|...||:|:
  Fly    31 NEKNWEWSYLVRKCRNLELEDSYDLYMRRLRVGYLSLFI-FIHVAVTVIHTLLLLTTPEIKYVYV 94

  Fly    89 NAIFDLGSLILVTGLLSINFFEDFVIRHRWVMTFTSTLSAYVVVLGDIAFNTYYYYKSNWPLNTL 153
            :.:..:.|.:::..:|.:||..:.|.:|.||:..||.|:..|:||.||..|.|:....|..||.:
  Fly    95 DMVAYMCSGLVIWVVLGVNFRSELVSKHGWVVYATSWLAVCVMVLMDIGLNVYHATSHNDILNPI 159

  Fly   154 YDVFVLCMIYMFLPIPSSKAAALLAISVSLTYVIYFIHFMAFNEHNVAKYVHGLDIVSIDFFHYL 218
            ||.:.|..||||:|:|......:|..:|:..|:|.:...:...:.|   .:|.:...:|    ||
  Fly   160 YDAYTLYAIYMFMPVPYLLQPFVLGSAVTFCYIINYSFVITAKDDN---QMHSILNEAI----YL 217

  Fly   219 G-FNMMGIFFRIMNDTMVRSSFLDRYQFITEEIWLRQARRQESLLLDSILPPQIAKPIQKSIKEK 282
            . .|::|||||:|.|..:|::||||.|::.|.:.||.||.||..||.||||.|||..:|:.:|.:
  Fly   218 SCVNLLGIFFRLMRDIALRTTFLDRRQYVEENLLLRYARDQERSLLLSILPAQIADRLQEDVKNR 282

  Fly   283 I--------IQPDNDFYHLGTSRTAENF-------MSIQIHNDVSILYADLVNYTQLTTTLTVEK 332
            |        .|...|......|:|.:.:       :.|:.|.||::||||:||||.|||||.|:|
  Fly   283 IERSKQQHQQQSQVDLRRSADSQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYTHLTTTLDVKK 347

  Fly   333 LVKVLHDLYARFDLAALSFKVQRIKFLGDCYYCVAGLGESDPDHATMAVSLGISMIANIKEVSVN 397
            ||:.||||:.|||:|:..:.|.|||||||||||||||...:.|||...|.||:.||.:|::|...
  Fly   348 LVEALHDLFVRFDIASEEYNVLRIKFLGDCYYCVAGLANPNADHAKCCVDLGLRMIKDIRDVREK 412

  Fly   398 RSLNIGMRIGVHSGTLFAGVIGKAKLQYDIWGADVNIASRLEATGSPGYVHVSGRTLSSLNAEEY 462
            |.|||.||||||||.:.:||||.||.|:|||..||:||:||||||:.|.||||.:|||.|:. ||
  Fly   413 RHLNIDMRIGVHSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQKTLSLLDG-EY 476

  Fly   463 NIYPGTESAQKDPVLQKHPMSTYLLTAIPSLDSDKTISIVEGVPNLDLQTVGSNRKSQILKPNLL 527
            ....|||.|::|||||||.:.|:|:.::.:...|         |...::.....:.|:..|.|.:
  Fly   477 FFEDGTEKAREDPVLQKHGIRTFLIKSLRAPMHD---------PRRRMRERQVKKLSEASKANFM 532

  Fly   528 SH---------------EMREEFRKMPVGGFKFQFPWSRRER----NLKNEKVERDLGIFCVAFK 573
            .:               ||..|..|||:|..:....:.|..|    .::.|...|::...|:.|:
  Fly   533 HNSTLHQYNQVRNQAKLEMCRELDKMPIGRIQLTKVFRRSTRLTQDEIEEETFRRNISSCCLFFR 597

  Fly   574 DKSVEWNYLHQPDYIFKYSVALGWGIGCCLIYIQSVNNSDIFYTGVVINIIAFFVLTFLLFICWY 638
            .::.|:.|:.:||.:.|||:||.|.|...|:.||.: :.|..|....|:.....:||.||.:.||
  Fly   598 IRNWEFQYIKEPDVMLKYSIALAWVIYMGLLTIQLL-SKDARYHYWYIDGTTIILLTMLLIVSWY 661

  Fly   639 KKVCW--WHSGQNEHRSYGKLSCAIFHLFEKIQHSFVLRLTVYMMIILCYYMVISLILMSCEKDQ 701
            ||: |  :.|..:.....|:||..:|.:.:::|.:.|:|:.:|.:||..|..|..:.::.|..|:
  Fly   662 KKL-WIMYMSDADVSSPNGRLSGFLFRMSDEMQRNVVIRVVMYFLIIFSYCAVAIMQVVGCSSDE 725

  Fly   702 YELDIIESKLYNY-DMDP-----FTCFHPWAYTNMMALILGMSYTFARIPFALKTFIGCAEAVVF 760
                       :| |:||     ..|||||..||.|.|::|||:.|.||||.:|:.......:.:
  Fly   726 -----------DYADLDPTYDERVQCFHPWILTNCMTLVIGMSFLFTRIPFIIKSCFSALIMIGY 779

  Fly   761 VLVVCFQYAFIFEHSVTTSPYLKAEIAHSCRVCMMLIT---MYAKERQSEFNTKMNYKLNLDLQN 822
            .::|..::.||:.:|.:|:....|:.:|   :.:|:||   .:..|||:||..|::|.....|..
  Fly   780 AVLVVSEFNFIYANSPSTNVNFNAKYSH---ILLMIITFGIFHLMERQTEFIAKVDYNWKRQLIK 841

  Fly   823 KQKSADVTNQSIIILLNNILPSHVVEVYLSSIAKHELYYENYRMVSVMFAMLTNFQMDLPSLRVL 887
            ||:.|.:||.:|.:||.||||:||.:.|||:..::|||||.|..|:||||.:.||..|...||||
  Fly   842 KQEDALITNDTIKVLLTNILPTHVADFYLSNQLQNELYYEEYDNVAVMFASIKNFDTDKIGLRVL 906

  Fly   888 NDIITAFDRLLSAYKQYYVVEKIKVVGCTYMAACGLDFSLIENLD-------------------- 932
            |:||..||.:|:.|.|...||||||...|||||||||.|..|.::
  Fly   907 NEIICDFDDVLNKYSQSLRVEKIKVANWTYMAACGLDVSRSEQVNAPQMKFRNVSLMPNGRRSRY 971

  Fly   933 -----SNS---------NFGSTSLSSELEQVR---------SRLESSIKEKNHDEVAFIMATFAL 974
                 ||:         |..:.:|..:||:.:         .|:.|:....:.:||..:||.|||
  Fly   972 DGARSSNADGVQRVPYGNGSNIALDLDLERGQYEGNVITSGPRISSTHNGSSSNEVVRVMAEFAL 1036

  Fly   975 DLMRVLSVCNKAYAGEPFDRALSTGEIRIGISTGQIMAGVVGASQPHYDIWGNPVNMASRMESTG 1039
            ||||.:...|.......::.:...|.:|||||.|:.||||||.|:||||||||||||||||:|||
  Fly  1037 DLMRTMRRFNTENMQTEYEGSTDYGMLRIGISHGRAMAGVVGISKPHYDIWGNPVNMASRMDSTG 1101

  Fly  1040 LSGHIQVTKETAQTLEEFDVMCYYRGLTFVKGRGEIPTYFVGIDKDLKFMSKKIDRLSENPSNP 1103
            :.|.||||:.||..|.||::.|.|||:|||||||.||||.:|||.:.:|       |...|:.|
  Fly  1102 VPGQIQVTENTALKLREFNIQCNYRGMTFVKGRGNIPTYIIGIDSEYQF-------LPHRPAAP 1158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AC_N	<42..291	CDD:292831	86/257 (33%)
		CYCc	262..464	CDD:214485	114/216 (53%)
		Nucleotidyl_cyc_III	306..489	CDD:299850	110/182 (60%)
		CYCc	831..1055	CDD:214485	116/266 (44%)
		Nucleotidyl_cyc_III	859..1080	CDD:299850	120/263 (46%)
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831	85/249 (34%)
		CYCc	254..476	CDD:214485	116/222 (52%)
		Nucleotidyl_cyc_III	321..503	CDD:299850	110/182 (60%)
		CYCc	856..1117	CDD:214485	114/260 (44%)
		Nucleotidyl_cyc_III	878..1142	CDD:299850	120/263 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449940
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27505
OrthoDB	1	1.010	-	-		D181177at33208
OrthoFinder	1	1.000	-	-		FOG0007605
OrthoInspector	1	1.000	-	-		otm48748
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45627
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.860