DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ACXA and gcy-5

DIOPT Version :9

Sequence 1:NP_620475.2 Gene:ACXA / 53432 FlyBaseID:FBgn0040510 Length:1112 Species:Drosophila melanogaster
Sequence 2:NP_496219.1 Gene:gcy-5 / 191643 WormBaseID:WBGene00001532 Length:1122 Species:Caenorhabditis elegans


Alignment Length:317 Identity:84/317 - (26%)
Similarity:150/317 - (47%) Gaps:52/317 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   247 TEEIWLRQARRQESLLLDSILPPQIAKPIQKSIKEKIIQPDNDFYHLGTSRTAENFMSIQIHNDV 311
            |:|:.|.  :::..:||..:||.|:|:.::..   :.::|             |.|      :.|
 Worm   847 TKELTLE--KKKADILLSRMLPKQVAERLKAG---QTVEP-------------EGF------DTV 887

  Fly   312 SILYADLVNYTQLTTTLTVEKLVKVLHDLYARFDLAALSFKVQRIKFLGDCYYCVAGL-GESDPD 375
            ::|::|:|.:|||....:..::|.:|:|||:.||.......|.:::.:||.|.||:|| .::...
 Worm   888 TVLFSDVVKFTQLAAKCSPFQVVNLLNDLYSNFDTIIEEHGVYKVESIGDGYLCVSGLPTKNGYA 952

  Fly   376 HATMAVSLGISMIANIKEVSVNR--SLNIGMRIGVHSGTLFAGVIGKAKLQYDIWGADVNIASRL 438
            |....|.:.:..:...|...|..  ...:.:|||::||...|||:|.:..:|.::|..||.|||:
 Worm   953 HIKQIVDMSLKFMDYCKSFKVPHLPREKVELRIGINSGPCVAGVVGLSMPRYCLFGDTVNTASRM 1017

  Fly   439 EATGSPGYVHVSGRTLSSLNAEEYNIYPGTESAQKDPVLQKHPMSTYLLTAIPSLDSD-KTISIV 502
            |:.|.|..:|:| ....||..:.|.....|.|..:..:..|..|.|:.:  :...||| |::|..
 Worm  1018 ESNGKPSMIHMS-EAAHSLLTDHYPHQYETSSRGEVIIKGKGVMETFWV--LGKTDSDTKSLSTR 1079

  Fly   503 EGVPNLDLQTVGSNRKSQILKPNLLSHEMREEFRKMPVGGFKFQFPWSRRERNLKNE 559
            ...|..|     .|...|          |:|:.:|..|      .|:..|:|:.|::
 Worm  1080 TTPPITD-----ENWPPQ----------MKEDLKKRAV------TPYPERQRSGKSK 1115

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ACXANP_620475.2 AC_N <42..291 CDD:292831 10/43 (23%)
CYCc 262..464 CDD:214485 59/204 (29%)
Nucleotidyl_cyc_III 306..489 CDD:299850 55/185 (30%)
CYCc 831..1055 CDD:214485
Nucleotidyl_cyc_III 859..1080 CDD:299850
gcy-5NP_496219.1 PBP1_NPR_GC_like 30..440 CDD:107347
ANF_receptor 49..426 CDD:279440
PK_GC 546..816 CDD:270894
HNOBA <830..873 CDD:285003 9/27 (33%)
CYCc 852..1042 CDD:214485 60/214 (28%)
Guanylate_cyc 879..1067 CDD:278633 58/209 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.