Protein Alignment ACXA and gcy-35

DIOPT Version :9

• Sequence 1: NP_620475.2
• Gene: ACXA / 53432
• FlyBaseID: FBgn0040510
• Length: 1112
• Species: Drosophila melanogaster
• Sequence 2: NP_001252131.1
• Gene: gcy-35 / 173202
• WormBaseID: WBGene00001555
• Length: 688
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 128/533 - (24%)
• Similarity: 219/533 - (41%)
• Gaps: 99/533 - (18%)

  Fly     7 YKTPYRERFRRCN--------LEYTNERLWEQSYLKARCKE----LHLEEEYMKYKIRLMISSLT 59
            |||..|....||:        |.|.::|......:|...:|    ::..|..||.:.|.. ..|.
 Worm   113 YKTKLRGPSFRCDVQADGTLLLHYYSKRSGLYPIVKGVVREVARRIYDTEVVMKVQERKQ-EHLD 176

  Fly    60 VFVPMLILLIVALQVIIWSFTEYTKYIYINAIFDLGSLILVTGLLSINFFEDFVIRHRWVMTFTS 124
            .||...::.::. |:   .....|:...|::..| ..:.|.||:..|: ..||.:...:.:.|..
 Worm   177 AFVTEHVVFVIT-QI---ENANSTQPKSISSKAD-SQIDLSTGIYEIS-SSDFSLAFPYHICFDP 235

  Fly   125 TLSAYVVVLGDIAFNTYYYYKSNWPLNTLYDVFVLCMIYMFLP-IPSSKAAALLAISVSLTYVIY 188
            .|  :|...|:       :.|..:|.....:..|..::.:..| :|.|..        |:.|  |
 Worm   236 DL--FVEHFGN-------FIKKTFPNAMRQETRVTDLLELVHPEVPFSYE--------SIKY--Y 281

  Fly   189 FIHFMAFNEHNVAKYVHGLD-----------IVSIDFFHYLGFNMMGIFFRIMNDTMVRS----- 237
            ......|....:...||..:           :|.||...|:      ::...:|.|.||.
 Worm   282 KNSLFVFRLKGLGDIVHNANDEAKTVLLKGSMVFIDEGKYI------LYMCSVNVTTVRELIERN 340

  Fly   238 ---SFLDRYQFITEEIWLRQARRQESLLLDSILPPQIAKPIQKSIKEKIIQPDN----------- 288
               |.:.|:....:.|.|.|:|..:..|..::  .:..|.::|..:|..|:...
 Worm   341 LHLSDMQRHDGTRDVIMLNQSRMSQVELNRTL--EETTKKLKKMAQELEIEKQKTDELLCELMPA 403

  Fly   289 ---DFYHLGTSRTAENFMSIQIHNDVSILYADLVNYTQLTTTLTVEKLVKVLHDLYARFD-LAAL 349
               |....|.:..|:.|.      |.::|:.|:|.:|.:....|...:|.:|:|||.||| |..|
 Worm   404 SVADSLRSGKAMDAKEFA------DCTLLFTDIVTFTNICAMCTPYDVVTLLNDLYLRFDRLVGL 462

  Fly   350 --SFKVQRIKFLGDCYYCVAGLGESDPDHATMAVSLGISMIANIKEV-SVNRSLNIGMRIGVHSG 411
              ::||:.|   ||.|..|.|:.|...:||...:::.|.|:...|.| |......|.:|:|||.|
 Worm   463 HDAYKVETI---GDAYMIVGGVPERCENHAERVLNISIGMLMESKLVLSPITHKPIKIRLGVHCG 524

  Fly   412 TLFAGVIGKAKLQYDIWGADVNIASRLEATGSPGYVHVS--GRTLSSLNAEEYNIYPGTESAQKD 474
            .:.|||:|....:|.::|..||:|:::|:.|....:|||  |: |:.|.|....::....:.:
 Worm   525 PVVAGVVGIKMPRYCLFGDTVNVANKMESNGIQCKIHVSETGK-LNGLKANPSYVFIDRGNTE-- 586

  Fly   475 PVLQKHPMSTYLL 487
             :..|..|.||.|
 Worm   587 -IRGKGMMYTYFL 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AC_N	<42..291	CDD:292831	53/282 (19%)
		CYCc	262..464	CDD:214485	65/221 (29%)
		Nucleotidyl_cyc_III	306..489	CDD:299850	61/188 (32%)
		CYCc	831..1055	CDD:214485
		Nucleotidyl_cyc_III	859..1080	CDD:299850
gcy-35	NP_001252131.1	HNOB	3..167	CDD:285002	13/53 (25%)
		HNOBA	218..409	CDD:285003	39/218 (18%)
		CYCc	388..579	CDD:214485	61/200 (31%)
		Guanylate_cyc	415..599	CDD:278633	63/197 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910