Protein Alignment ACXA and gucy1a2

DIOPT Version :10

• Sequence 1: NP_620475.2
• Gene: ACXA / 53432
• FlyBaseID: FBgn0040510
• Length: 1112
• Species: Drosophila melanogaster
• Sequence 2: NP_001120379.1
• Gene: gucy1a2 / 100145454
• XenbaseID: XB-GENE-1011801
• Length: 712
• Species: Xenopus tropicalis
• Alignment Length: 283
• Identity: 73/283 - (25%)
• Similarity: 125/283 - (44%)
• Gaps: 49/283 - (17%)

  Fly   252 LRQARRQESLLLDSILPPQIAKPIQKSIKEKIIQPDNDFYHLGTSRTAENFMSIQIHNDVSILYA 316
            |.:.:::...||.||.|..:|:.:.:                |.|..|..|      :||::|::
 Frog   463 LEEEKKKTVDLLYSIFPGDVAQQLWE----------------GKSVQARKF------DDVTMLFS 505

  Fly   317 DLVNYTQLTTTLTVEKLVKVLHDLYARFDLAALSFKVQRIKFLGDCYYCVAGLGESDPDHATMAV 381
            |:|.:|.:....|..:::.:|::||.|||.......:.:::.:||.|...|||......||....
 Frog   506 DIVGFTAVCAQCTPMQVISMLNELYTRFDYQCGFLDIYKVETIGDAYCVAAGLLRQSNSHAKPIA 570

  Fly   382 SLGISMIANIKEVSVNRSLNIGMRIGVHSGTLFAGVIGKAKLQYDIWGADVNIASRLEATGSPGY 446
            .:.:.|:...:||.......|.||||:|||::.|||:|....:|.::|.:|.:||:.|:...|..
 Frog   571 LMALKMMELSEEVLTPDGRPIKMRIGIHSGSVLAGVVGVRMPRYCLFGNNVTLASKFESGSHPRR 635

  Fly   447 VHVSGRTLSSLNAE-EYNIYPGTESAQKDPVLQKHPMSTYLLTAIPSLDSDKTISIVEGVPNLDL 510
            ::||..|...|..| .::..|.:.....|...::.|...|.|.|
 Frog   636 INVSPTTYQLLKDEANFHFVPRSREELPDNFPKEIPGICYFLEA--------------------- 679

  Fly   511 QTVGSNRKSQILKPNLLSHEMRE 533
               .|.:|..  ||:|.|..||:
 Frog   680 ---DSGQKQP--KPSLTSVRMRK 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXA	NP_620475.2	AcyC	88..457	CDD:441717	57/204 (28%)
		Nucleotidyl_cyc_III	306..489	CDD:448371	53/183 (29%)
		Nucleotidyl_cyc_III	859..1080	CDD:448371
gucy1a2	NP_001120379.1	Pap_E4	30..>86	CDD:367150
		HNOB	<137..248	CDD:462233
		HNOBA	296..486	CDD:462234	7/22 (32%)
		Guanylate_cyc	492..679	CDD:425528	55/192 (29%)