Protein Alignment wds and Poc1b

DIOPT Version :10

• Sequence 1: NP_524984.1
• Gene: wds / 53428
• FlyBaseID: FBgn0040066
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_082016.1
• Gene: Poc1b / 382406
• MGIID: 1918511
• Length: 476
• Species: Mus musculus
• Alignment Length: 298
• Identity: 90/298 - (30%)
• Similarity: 149/298 - (50%)
• Gaps: 8/298 - (2%)

  Fly    64 LKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRL 128
            |:.:..||..|:::..||||.:.:|::|.|..:.:|............|||..::.:.:|....|
Mouse    10 LERSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQGNL 74

  Fly   129 LVSGSDDKTLKVWELS-TGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLK 192
            |.|.|.|:|:::|.|. .||| ...|.|:..|...:|:....|:|:.|.|:|:::|.:...:.|.
Mouse    75 LASASRDRTVRLWVLDRKGKS-SEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSMFRQRFLY 138

  Fly   193 TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYIL 257
            :|..|:..|....|:.||.||||.|.|...:||||.:.||:.. ..|.....:||.|:|||..|.
Mouse   139 SLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNN-FSDSVGFANFVDFNPNGTCIA 202

  Fly   258 AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQ 322
            :|..|:.:|:||....|.|:.|..|.....|:  :|...|.. :|:.|.|..|.:.:|....::.
Mouse   203 SAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCL--SFHPLGNS-LVTASSDGTVKMLDLIEGRLIY 264

  Fly   323 KLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKSD 360
            .|||||..|...:......::.|...  |..:.:|:::
Mouse   265 TLQGHTGPVFTVSFSKDGELLTSGGA--DAQVLIWRTN 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wds	NP_524984.1	WD40	<63..361	CDD:441893	90/298 (30%)
		WD40 repeat	75..112	CDD:293791	8/36 (22%)
		WD40 repeat	118..154	CDD:293791	12/36 (33%)
		WD40 repeat	159..195	CDD:293791	9/35 (26%)
		WD40 repeat	202..237	CDD:293791	15/34 (44%)
		WD40 repeat	244..280	CDD:293791	14/35 (40%)
		WD40 repeat	288..325	CDD:293791	8/36 (22%)
		WD40 repeat	331..357	CDD:293791	3/25 (12%)
Poc1b	NP_082016.1	WD40	<5..300	CDD:441893	90/296 (30%)
		WD 1	16..55		11/38 (29%)
		WD40 repeat	21..58	CDD:293791	8/36 (22%)
		WD 2	58..97		15/39 (38%)
		WD40 repeat	63..100	CDD:293791	12/37 (32%)
		WD 3	100..139		10/38 (26%)
		WD40 repeat	106..142	CDD:293791	9/35 (26%)
		WD 4	142..181		17/38 (45%)
		WD40 repeat	147..182	CDD:293791	16/35 (46%)
		WD 5	183..223		15/39 (38%)
		WD40 repeat	190..225	CDD:293791	14/34 (41%)
		WD 6	226..265		9/41 (22%)
		WD40 repeat	231..267	CDD:293791	8/38 (21%)
		WD 7	268..307		7/35 (20%)
		WD40 repeat	273..299	CDD:293791	4/27 (15%)