DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wds and CG10931

DIOPT Version :9

Sequence 1:	NP_001245503.1	Gene:	wds / 53428	FlyBaseID:	FBgn0040066	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_611261.1	Gene:	CG10931 / 37024	FlyBaseID:	FBgn0034274	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	168/303 - (55%)
Similarity:	230/303 - (75%)	Gaps:	1/303 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 SVKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVA 121
            |:.|.|.:|.:|.||:..|:.:|||.|||.|.|||.|:|:|:|.....:..::::||..|::|||
  Fly    41 SMSPGYAIKHSLLGHSGCVTGLKFSSNGENLVSSSGDRLLKLWDLSATRCIQSLAGHGDGVNDVA 105

  Fly   122 WSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVR 186
            ||: :.|:.|.|||.|:::|:..:...:|.|:|||.|.|.|.||||:||:.|.||||:||:||||
  Fly   106 WSA-AGLIASCSDDMTVRLWDARSKLCVKVLEGHSRYSFSCCFNPQANLLASTSFDETVRLWDVR 169

  Fly   187 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSP 251
            |||.||.:.||.||:::|.|:|||::.|:||||||.|:||:::|..||||:|.||.||.:|||||
  Fly   170 TGKTLKIVHAHQDPITSVDFHRDGNIFVTSSYDGLVRLWDSSTGHVLKTLVDVDNIPVGYVKFSP 234

  Fly   252 NGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQ 316
            ||:|||::||:|||:||:|.|.||::||.||.||.||..:|||.|||.|||||||||.:.|||||
  Fly   235 NGRYILSSTLNNTLRLWNYKKPKCMRTYRGHLNEFYCSNSNFSTTGGIWIVSGSEDNTLCIWNLQ 299

  Fly   317 SKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKS 359
            ::|:|||:....|.:|.|.||||.|:|||.||:|...||:|||
  Fly   300 TRELVQKISTEGDQILSTHCHPTANVIASGALQNSYAIKIWKS 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wds	NP_001245503.1	WD40	64..358	CDD:238121	162/293 (55%)
		WD40 repeat	75..112	CDD:293791	15/36 (42%)
		WD40 repeat	118..154	CDD:293791	14/35 (40%)
		WD40 repeat	159..195	CDD:293791	24/35 (69%)
		WD40 repeat	202..237	CDD:293791	19/34 (56%)
		WD40 repeat	244..280	CDD:293791	23/35 (66%)
		WD40 repeat	288..325	CDD:293791	25/36 (69%)
		WD40 repeat	331..357	CDD:293791	15/25 (60%)
CG10931	NP_611261.1	WD40	<48..341	CDD:225201	162/293 (55%)
		WD40	49..341	CDD:238121	162/292 (55%)
		WD40 repeat	59..96	CDD:293791	15/36 (42%)
		WD40 repeat	102..137	CDD:293791	14/35 (40%)
		WD40 repeat	142..178	CDD:293791	24/35 (69%)
		WD40 repeat	185..220	CDD:293791	19/34 (56%)
		WD40 repeat	227..263	CDD:293791	23/35 (66%)
		WD40 repeat	271..309	CDD:293791	25/37 (68%)
		WD40 repeat	314..340	CDD:293791	15/25 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0266
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I823
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53955
OrthoDB	1	1.010	-	-		D368256at33208
OrthoFinder	1	1.000	-	-		FOG0002159
OrthoInspector	1	1.000	-	-		otm46811
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22847
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.910