DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wds and Wdsub1

DIOPT Version :9

Sequence 1:NP_001245503.1 Gene:wds / 53428 FlyBaseID:FBgn0040066 Length:361 Species:Drosophila melanogaster
Sequence 2:NP_001014201.1 Gene:Wdsub1 / 362137 RGDID:1359296 Length:476 Species:Rattus norvegicus


Alignment Length:323 Identity:91/323 - (28%)
Similarity:142/323 - (43%) Gaps:47/323 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    67 TLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKF----EKTISGHKLGISDVAWSSDSR 127
            |||.|...||...||  ...||:.|.||.|:::...|  |    ...:..|...:...::|....
  Rat     7 TLADHGDDVSCCAFS--STLLATCSLDKTIRLYSLSD--FAELPHSPLKFHTYAVHCCSFSPSGH 67

  Fly   128 LLVSGSDDKTLKVWELSTGKSLKTLK--GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKC 190
            :|.|.|.|.|..:|...:|.:|..|:  |.|....|| |:|.|..:.||:.|.||.:|:..:.|.
  Rat    68 VLASCSTDGTTVLWSAHSGHTLTVLEQPGGSPVRVCC-FSPDSTYLASGAADGSVVLWNAHSYKL 131

  Fly   191 LKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLK---------TLIDDDNPPVSF 246
            .:........:.|..|:.||.|:|:.|..|...:||... :||.         |.....:.|:| 
  Rat   132 YRCGSVKDSSLVACAFSPDGGLLVTGSSGGDLTVWDDRM-RCLHSEKAHDLGITCCSFSSQPLS- 194

  Fly   247 VKFSPNGK-----YILAAT-LDNTLKLWDYSKGKCL-------KTYTGH-KNEKYCIFANFSVTG 297
                 .|:     |.||:. .|..:|||..|..:.|       .|.:|| .....|.|::    .
  Rat   195 -----GGEHGLQLYRLASCGQDCEIKLWVVSFTRVLGFELKYRSTLSGHCAPVLACAFSH----D 250

  Fly   298 GKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKSD 360
            |:.:.|||.|..|.|:::.::.|:..|..||..|...|..|...::|:.::  |||:.:|:.|
  Rat   251 GQMLASGSVDKSVIIYDIGTQSVLHTLTQHTRYVTTCAFAPNTLLLATGSM--DKTVNIWQFD 311

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdsNP_001245503.1 WD40 64..358 CDD:238121 89/319 (28%)
WD40 repeat 75..112 CDD:293791 12/40 (30%)
WD40 repeat 118..154 CDD:293791 10/37 (27%)
WD40 repeat 159..195 CDD:293791 12/35 (34%)
WD40 repeat 202..237 CDD:293791 13/43 (30%)
WD40 repeat 244..280 CDD:293791 12/48 (25%)
WD40 repeat 288..325 CDD:293791 10/36 (28%)
WD40 repeat 331..357 CDD:293791 7/25 (28%)
Wdsub1NP_001014201.1 WD40 4..309 CDD:238121 89/319 (28%)
WD 1 10..47 13/40 (33%)
WD40 repeat 16..52 CDD:293791 11/39 (28%)
WD 2 52..91 10/38 (26%)
WD40 repeat 57..93 CDD:293791 9/35 (26%)
WD 3 95..134 14/39 (36%)
WD40 repeat 101..136 CDD:293791 12/35 (34%)
WD 4 137..176 12/39 (31%)
WD40 repeat 143..177 CDD:293791 12/34 (35%)
WD 5 178..228 13/55 (24%)
WD40 repeat 183..236 CDD:293791 14/58 (24%)
WD 6 237..276 12/42 (29%)
WD40 repeat 242..266 CDD:293791 8/27 (30%)
WD 7 279..318 11/35 (31%)
WD40 repeat 284..308 CDD:293791 7/25 (28%)
SAM_WDSUB1 328..399 CDD:188904
U-box 404..476 CDD:398320
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D957291at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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