DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wds and Wdr81

DIOPT Version :9

Sequence 1:	NP_001245503.1	Gene:	wds / 53428	FlyBaseID:	FBgn0040066	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_609535.1	Gene:	Wdr81 / 34616	FlyBaseID:	FBgn0032395	Length:	1953	Species:	Drosophila melanogaster

Alignment Length:	252	Identity:	53/252 - (21%)
Similarity:	105/252 - (41%)	Gaps:	54/252 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 NKSSLSVKPNYTLKF------TLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAY---DGK-- 105
            |:::.:.|...||..      :..|||.:|.|:....|.....|:|.||.:|:|...   ||:
  Fly  1632 NETTRNEKDTQTLNLKQIRLQSFVGHTNSVRAIYALDNENSFISASKDKTVKLWSLRSEGDGRKT 1696

  Fly   106 --FEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKG--HSNYVFCCNFNP 166
              .:.|.:.||..|:.:.:....|.:|  |.|..:.:|:...|:.|..|..  ||..........
  Fly  1697 SACQFTYTAHKKSINSLGFLESLRYVV--SCDSGIHLWDPFIGRPLSVLDAPRHSAVTVVKCLPS 1759

  Fly   167 QSNLIVSGSFDESVRIWDVR------------------TGKCLKTLPAHSDPVSAVHFNRDGSLI 213
            .|.|:::|:.:.:|::.|.|                  |.:||...|:             |:.:
  Fly  1760 HSPLVIAGTAESTVKMVDARSCEYVNEWRVCNASLPNATVRCLAVAPS-------------GNWL 1811

  Fly   214 VSSSYDGLCRIWDTASGQCLKTL--IDDDNPPVSFVKFSPNGKYILAATLDNTLKLW 268
            .:....|.....||.:|..:.:.  ::.|...::    :|:.::::::.||::|.:|
  Fly  1812 AAGLSSGCIVQLDTRTGMVINSWRPMECDLLQLA----APSDQFLVSSALDHSLAVW 1864

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wds	NP_001245503.1	WD40	64..358	CDD:238121	50/240 (21%)
		WD40 repeat	75..112	CDD:293791	12/43 (28%)
		WD40 repeat	118..154	CDD:293791	8/35 (23%)
		WD40 repeat	159..195	CDD:293791	9/53 (17%)
		WD40 repeat	202..237	CDD:293791	5/36 (14%)
		WD40 repeat	244..280	CDD:293791	5/25 (20%)
		WD40 repeat	288..325	CDD:293791
		WD40 repeat	331..357	CDD:293791
Wdr81	NP_609535.1	Beach	345..588	CDD:100117
		WD40	<1644..1877	CDD:225201	50/240 (21%)
		WD40	1651..1876	CDD:295369	49/233 (21%)
		WD40 repeat	1662..1705	CDD:293791	11/42 (26%)
		WD40 repeat	1710..1744	CDD:293791	8/35 (23%)
		WD40 repeat	1752..1788	CDD:293791	6/35 (17%)
		WD40 repeat	1799..1836	CDD:293791	8/49 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442354
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840