DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wds and CG3436

DIOPT Version :9

Sequence 1:	NP_001245503.1	Gene:	wds / 53428	FlyBaseID:	FBgn0040066	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_001285543.1	Gene:	CG3436 / 33180	FlyBaseID:	FBgn0031229	Length:	347	Species:	Drosophila melanogaster

Alignment Length:	301	Identity:	99/301 - (32%)
Similarity:	157/301 - (52%)	Gaps:	13/301 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 LAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSDSRLLVS 131
            |.||...:...:|.|.||.|.||..|:.|.||..| |.:....:|||...:.:..::.|...:.:
  Fly    51 LEGHEGEIFTAEFHPEGELLLSSGFDRQIYIWQVYEDCENVMAMSGHSGAVMEAHFTPDGSHIFT 115

  Fly   132 GSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIWDVRTGKCLKTLP 195
            .|.||||..|:::||:..:..|||.|:|.....:.: ..|:.|||.|.:::|||.|......||.
  Fly   116 CSTDKTLAFWDIATGQRQRRFKGHGNFVNSVQGSRRGQQLLCSGSDDRTIKIWDARKKHAAHTLE 180

  Fly   196 AHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAAT 260
            :... |:||.|...|..::|...|...:|||... |.:...:...:..::.:..||.|.:||...
  Fly   181 SPFQ-VTAVCFGDTGEQVISGGIDNEVKIWDIRK-QAVLHHLRGHSDTITGMSLSPEGDFILTNA 243

  Fly   261 LDNTLKLWD---YSKG-KCLKTYTGHKN--EKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKE 319
            :||||::||   |:.| :|:|.:.||::  ||..:...:| .|...|.|||.|..||||::.::.
  Fly   244 MDNTLRVWDVRPYAPGERCVKVFQGHQHNFEKNLLRCAWS-PGSDKITSGSADRHVYIWDVNTRR 307

  Fly   320 VVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKSD 360
            ::.||.||..:|......|.|.:|.|.:  :|||:.|.:.|
  Fly   308 ILYKLPGHNGSVNAVDFSPKEPLILSGS--SDKTLYLGEID 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wds	NP_001245503.1	WD40	64..358	CDD:238121	98/297 (33%)
		WD40 repeat	75..112	CDD:293791	13/37 (35%)
		WD40 repeat	118..154	CDD:293791	9/35 (26%)
		WD40 repeat	159..195	CDD:293791	11/36 (31%)
		WD40 repeat	202..237	CDD:293791	10/34 (29%)
		WD40 repeat	244..280	CDD:293791	15/39 (38%)
		WD40 repeat	288..325	CDD:293791	12/36 (33%)
		WD40 repeat	331..357	CDD:293791	8/25 (32%)
CG3436	NP_001285543.1	WD40	<19..346	CDD:225201	98/299 (33%)
		WD40	50..342	CDD:238121	97/295 (33%)
		WD40 repeat	58..96	CDD:293791	13/37 (35%)
		WD40 repeat	102..138	CDD:293791	9/35 (26%)
		WD40 repeat	143..180	CDD:293791	11/36 (31%)
		WD40 repeat	186..221	CDD:293791	10/35 (29%)
		WD40 repeat	227..267	CDD:293791	15/39 (38%)
		WD40 repeat	277..313	CDD:293791	12/36 (33%)
		WD40 repeat	319..342	CDD:293791	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442323
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46868
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840