DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wds and wsb1

DIOPT Version :9

Sequence 1:NP_001245503.1 Gene:wds / 53428 FlyBaseID:FBgn0040066 Length:361 Species:Drosophila melanogaster
Sequence 2:NP_955927.1 Gene:wsb1 / 323226 ZFINID:ZDB-GENE-030131-1946 Length:423 Species:Danio rerio


Alignment Length:348 Identity:96/348 - (27%)
Similarity:149/348 - (42%) Gaps:55/348 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 SGPNSL-QPNSVGQ--PGAT-------------TSSNSSASNKSSLSVKPNYTLKFTLAGHTKAV 75
            :||..| :.||.|.  ||..             .:..||...|.|..|...:             
Zfish    81 AGPRRLSRQNSEGSLLPGEPREHTIDCGDIVWGLAFGSSVPEKQSRCVNIEW------------- 132

  Fly    76 SAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD-SRLLVSGSDDKTLK 139
            ...||..:...||:...:..||||..|.||....:..|...:.|:.::.| |.:|||.|.||||:
Zfish   133 HRFKFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLMDHTDIVRDLTFAPDGSLVLVSASRDKTLR 197

  Fly   140 VWEL-STGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSA 203
            ||:| ..|..:|.|:||.|:|:|..|:|.|:::.|....::|.:||:.....::.|..|.:.|..
Zfish   198 VWDLKDDGNMVKVLRGHQNWVYCSAFSPDSSVLCSVGAGKAVFLWDMDKYTLIRKLEGHHNDVVC 262

  Fly   204 VHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP------------VSFVKFSPNGKYI 256
            ..|:.||:|:.::|||....:||..:...|..|.....||            |..|.|..:|::|
Zfish   263 CEFSPDGALLATASYDTRVIVWDPHTATVLLELGHLFPPPSPIFAGGANDRWVRSVAFCHDGRHI 327

  Fly   257 LAATLDNTLKLW--DYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKE 319
            .:.|.|..::.|  |....:.:...|   |...|.|:    |.|..:.:||.|..|:.|  .|..
Zfish   328 ASVTDDRLVRFWSIDEKSPQAIGPLT---NGLCCAFS----TDGSVLSAGSRDGSVHFW--ASPR 383

  Fly   320 VVQKLQGHTDTVLCTACHPTENI 342
            .:..|| |...:......||:.:
Zfish   384 SIASLQ-HLCRMTLRRVMPTQQV 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdsNP_001245503.1 WD40 64..358 CDD:238121 83/295 (28%)
WD40 repeat 75..112 CDD:293791 11/36 (31%)
WD40 repeat 118..154 CDD:293791 17/37 (46%)
WD40 repeat 159..195 CDD:293791 9/35 (26%)
WD40 repeat 202..237 CDD:293791 10/34 (29%)
WD40 repeat 244..280 CDD:293791 9/37 (24%)
WD40 repeat 288..325 CDD:293791 10/36 (28%)
WD40 repeat 331..357 CDD:293791 2/12 (17%)
wsb1NP_955927.1 WD40 38..379 CDD:225201 89/317 (28%)
WD40 repeat 38..71 CDD:293791
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 76..100 8/18 (44%)
WD 1 125..166 13/53 (25%)
WD40 repeat 135..169 CDD:293791 11/33 (33%)
WD40 136..379 CDD:238121 76/249 (31%)
WD 2 169..209 16/39 (41%)
WD40 repeat 175..213 CDD:293791 17/37 (46%)
WD 3 213..252 12/38 (32%)
WD40 repeat 218..254 CDD:293791 9/35 (26%)
WD 4 255..294 12/38 (32%)
WD40 repeat 261..296 CDD:293791 10/34 (29%)
WD 5 310..347 9/36 (25%)
WD40 repeat 315..353 CDD:293791 9/37 (24%)
SOCS_WSB1_SWIP1 383..422 CDD:239715 5/24 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.