DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wds and Wdr27

DIOPT Version :9

Sequence 1:NP_001245503.1 Gene:wds / 53428 FlyBaseID:FBgn0040066 Length:361 Species:Drosophila melanogaster
Sequence 2:XP_008757027.1 Gene:Wdr27 / 308222 RGDID:1309633 Length:818 Species:Rattus norvegicus


Alignment Length:384 Identity:88/384 - (22%)
Similarity:140/384 - (36%) Gaps:118/384 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 SNSSASNKSSLSVKPNYTLK--------------FTLAGHTKAVSAVKFSPNGEWLASSSADKLI 96
            :|...:|:.|...|.||..|              ..:|....||:.::||.:|:.||....:.|.
  Rat   464 TNIKHNNRRSSKYKNNYKCKEYSESFLPRNLIRQVAVAQAPVAVTCLQFSGDGQQLACGLGNHLS 528

  Fly    97 KIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWE------------------- 142
            .::.|.........|||...::.|.||.|.|.|:|.:.|:||:||.                   
  Rat   529 LVFDASLSGAPAAFSGHDGAVNTVCWSHDKRWLLSTARDRTLRVWSVPRTEFVMLLAADAFPKPV 593

  Fly   143 -------------LSTGKSLKTLKGHSNYVFCC-----NFNPQ---------------------- 167
                         ||:|.....||.|   :..|     .:.|:                      
  Rat   594 ASAQFYYMDTFILLSSGPEFCLLKYH---IDLCRDDIRRYKPKSRYKPIFRLPTTSAADITSLSA 655

  Fly   168 -----SNLIVSGSFDESVRIWDVRTGKCLKTLPA--HSDPVSAVHFNRDGSLIVSSSYDGLCRIW 225
                 |::|::...|.:|.::|:..| |...:.|  ||.||..:..|:..|.|...|        
  Rat   656 VNDFYSHIILTAGRDRTVEVFDLNAG-CSAAVLAEVHSRPVHRICQNKGSSFIAQQS-------- 711

  Fly   226 DTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF 290
             .|....|.|.:.|.                        ::|||....:|::.:.||.|..|...
  Rat   712 -LAYNLFLTTAVGDG------------------------VRLWDLRNLRCVRCFEGHPNRSYPCG 751

  Fly   291 ANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALE 349
            ..||.. ||.:..|:||...|::.:.|...:.:|.||||||...|.:|..:.:.:|.|:
  Rat   752 VAFSPC-GKLMACGAEDRHAYVYEMGSSSFLYRLAGHTDTVTEVAFNPAASQLITATLD 809

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdsNP_001245503.1 WD40 64..358 CDD:238121 82/366 (22%)
WD40 repeat 75..112 CDD:293791 8/36 (22%)
WD40 repeat 118..154 CDD:293791 16/67 (24%)
WD40 repeat 159..195 CDD:293791 9/67 (13%)
WD40 repeat 202..237 CDD:293791 7/34 (21%)
WD40 repeat 244..280 CDD:293791 4/35 (11%)
WD40 repeat 288..325 CDD:293791 9/36 (25%)
WD40 repeat 331..357 CDD:293791 5/19 (26%)
Wdr27XP_008757027.1 WD40 <45..229 CDD:421866
WD40 repeat 67..112 CDD:293791
WD40 repeat 120..154 CDD:293791
WD40 repeat 160..193 CDD:293791
WD40 repeat 204..230 CDD:293791
WD40 508..815 CDD:421866 78/340 (23%)
WD40 repeat 508..544 CDD:293791 7/35 (20%)
WD40 repeat 550..632 CDD:293791 19/84 (23%)
WD40 repeat 650..688 CDD:293791 7/38 (18%)
WD40 repeat 696..741 CDD:293791 12/77 (16%)
WD40 repeat 749..785 CDD:293791 9/36 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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