DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wds and Dcaf11

DIOPT Version :9

Sequence 1:NP_001245503.1 Gene:wds / 53428 FlyBaseID:FBgn0040066 Length:361 Species:Drosophila melanogaster
Sequence 2:NP_001009686.1 Gene:Dcaf11 / 305895 RGDID:1311288 Length:549 Species:Rattus norvegicus


Alignment Length:360 Identity:81/360 - (22%)
Similarity:147/360 - (40%) Gaps:71/360 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 PNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFE--KTISGHKLG--ISDV 120
            || .|.||.....||...: :|.:|:...|:..|:.|:::....|:|.  |:|....:|  :.||
  Rat   162 PN-DLSFTDTYSQKAFCGI-YSKDGQIFMSACQDQTIRLYDCRYGRFHKFKSIKARDVGWSVLDV 224

  Fly   121 AWSSDSRLLVSGSDDKTLKVWEL----STGKSLKTLKGHSNY-VFCCNFNPQSNLIVSGSFDESV 180
            |::.|....:..|....:.:..:    .|..:|........: ||....:.....::.|:.|..:
  Rat   225 AFTPDGNHFLYSSWSDYIHICSIYGEGDTHTALDLRPDERRFAVFSIAVSSDGREVLGGANDGCL 289

  Fly   181 RIWDVRTGKCLKTLPAHSDPVSAVHF-NRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV 244
            .::|....:....:.:|.|.|:||.| :....::.|...|.:|::||.      :|:.:||..||
  Rat   290 YVFDREQNRRTLQIESHEDDVNAVAFADISSQILFSGGDDAICKVWDR------RTMREDDPKPV 348

  Fly   245 ----------SFVKFSPNGKYILAATLDNTLKLWDYSK--------------------------- 272
                      :|:....:.:|:::.:.|.|:||||..:                           
  Rat   349 GALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRLAATQQNWDYRWQQVP 413

  Fly   273 -----------GKCLKTYTGH---KNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQK 323
                       ...|.||.||   .....|.|:....||.::|.||.....|.:::|.|..:|:|
  Rat   414 KKAWKKLKLPGDSSLMTYRGHGVLHTLIRCRFSPAHSTGQQFIYSGCSTGKVVVYDLLSGHIVKK 478

  Fly   324 LQGHTDTVLCTACHPTENIIASAALENDKTIKLWK 358
            |..|...|...:.||.|..|.|::.  |.:::||:
  Rat   479 LTNHKACVRDVSWHPFEEKIVSSSW--DGSLRLWQ 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdsNP_001245503.1 WD40 64..358 CDD:238121 78/354 (22%)
WD40 repeat 75..112 CDD:293791 9/38 (24%)
WD40 repeat 118..154 CDD:293791 7/39 (18%)
WD40 repeat 159..195 CDD:293791 5/35 (14%)
WD40 repeat 202..237 CDD:293791 9/35 (26%)
WD40 repeat 244..280 CDD:293791 11/83 (13%)
WD40 repeat 288..325 CDD:293791 12/36 (33%)
WD40 repeat 331..357 CDD:293791 7/25 (28%)
Dcaf11NP_001009686.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..40
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 80..100
WD 1 170..210 9/40 (23%)
WD40 180..511 CDD:421866 73/338 (22%)
WD40 repeat 180..214 CDD:293791 9/33 (27%)
WD 2 216..258 7/41 (17%)
WD40 repeat 221..263 CDD:293791 7/41 (17%)
WD 3 263..302 5/38 (13%)
WD40 repeat 269..305 CDD:293791 4/35 (11%)
WD 4 305..345 13/45 (29%)
WD40 repeat 310..352 CDD:293791 14/47 (30%)
WD 5 353..392 8/38 (21%)
WD40 repeat 359..394 CDD:293791 8/34 (24%)
WD 6 435..480 12/44 (27%)
WD40 repeat 444..470 CDD:293791 7/25 (28%)
WD 7 481..520 10/33 (30%)
WD40 repeat 486..510 CDD:293791 7/25 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.