DRSC/TRiP Functional Genomics Resources

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Protein Alignment wds and Dcaf11

DIOPT Version :9

Sequence 1:NP_001245503.1 Gene:wds / 53428 FlyBaseID:FBgn0040066 Length:361 Species:Drosophila melanogaster
Sequence 2:NP_001185938.1 Gene:Dcaf11 / 28199 MGIID:90168 Length:549 Species:Mus musculus


Alignment Length:381 Identity:82/381 - (21%)
Similarity:145/381 - (38%) Gaps:113/381 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 PNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFE--KTISGHKLG--ISDV 120
            || .|.||.....||...: :|.:|:...|:..|:.|:::....|:|.  |:|....:|  :.||
Mouse   162 PN-DLSFTDTYSQKAFCGI-YSKDGQIFMSACQDQTIRLYDCRYGRFHKFKSIKARDVGWSVLDV 224

  Fly   121 AWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNL--------------- 170
            |::.|....:..|       |              |:|:..||...:.:.               
Mouse   225 AFTPDGNHFLYSS-------W--------------SDYIHICNIYGEGDTHTALDLRPDERRFAV 268

  Fly   171 -----------IVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHF-NRDGSLIVSSSYDGLCR 223
                       ::.|:.|..:.::|....:....:.:|.|.|:||.| :....::.|...|.:|:
Mouse   269 FSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADISSQILFSGGDDAICK 333

  Fly   224 IWDTASGQCLKTLIDDDNPPV----------SFVKFSPNGKYILAATLDNTLKLWDYSK------ 272
            :||.      :|:.:||..||          :|:....:.:|:::.:.|.|:||||..:      
Mouse   334 VWDR------RTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREG 392

  Fly   273 --------------------------------GKCLKTYTGH---KNEKYCIFANFSVTGGKWIV 302
                                            ...|.||.||   .....|.|:....||.::|.
Mouse   393 MEASRLAATQQNWDYRWQQVPKIAWKKLKLPGDSSLMTYRGHGVLHTLIRCRFSPAHSTGQQFIY 457

  Fly   303 SGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWK 358
            ||.....|.:::|.|..:|:||..|...|...:.||.|..|.|::.  |..::||:
Mouse   458 SGCSTGKVVVYDLLSGHIVKKLTNHKACVRDVSWHPFEEKIVSSSW--DGNLRLWQ 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdsNP_001245503.1 WD40 64..358 CDD:238121 79/375 (21%)
WD40 repeat 75..112 CDD:293791 9/38 (24%)
WD40 repeat 118..154 CDD:293791 6/35 (17%)
WD40 repeat 159..195 CDD:293791 5/61 (8%)
WD40 repeat 202..237 CDD:293791 9/35 (26%)
WD40 repeat 244..280 CDD:293791 11/83 (13%)
WD40 repeat 288..325 CDD:293791 12/36 (33%)
WD40 repeat 331..357 CDD:293791 7/25 (28%)
Dcaf11NP_001185938.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..40
WD 1 170..210 9/40 (23%)
WD40 171..511 CDD:392136 76/369 (21%)
WD40 repeat 177..214 CDD:293791 9/37 (24%)
WD 2 216..258 11/62 (18%)
WD40 repeat 221..263 CDD:293791 10/62 (16%)
WD 3 263..302 3/38 (8%)
WD40 repeat 269..305 CDD:293791 3/35 (9%)
WD 4 305..345 13/45 (29%)
WD40 repeat 310..352 CDD:293791 14/47 (30%)
WD 5 353..392 8/38 (21%)
WD40 repeat 359..391 CDD:293791 8/31 (26%)
WD 6 435..480 12/44 (27%)
WD40 repeat 444..470 CDD:293791 7/25 (28%)
WD 7 481..520 10/33 (30%)
WD40 repeat 486..510 CDD:293791 7/25 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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