DRSC/TRiP Functional Genomics Resources

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Protein Alignment wds and Ambra1

DIOPT Version :9

Sequence 1:NP_001245503.1 Gene:wds / 53428 FlyBaseID:FBgn0040066 Length:361 Species:Drosophila melanogaster
Sequence 2:NP_766257.3 Gene:Ambra1 / 228361 MGIID:2443564 Length:1300 Species:Mus musculus


Alignment Length:164 Identity:49/164 - (29%)
Similarity:75/164 - (45%) Gaps:19/164 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   120 VAWSSD--------SRLLVSGSDDKT--LKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSG 174
            :.|..:        .|||....:|||  :| ||   ||.:: |.......|...|:|...|:.|.
Mouse    12 ILWGRERGTRAMGAQRLLQELVEDKTRWMK-WE---GKRVE-LPDSPRSTFLLAFSPDRTLLAST 71

  Fly   175 SFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRD-GSLIVSSSYDGLCRIWDTASGQCLKTLID 238
            ..:.::.|.:|:||||:.:|..|......|.|:.. ..||.|...||..||||...|.  ::...
Mouse    72 HVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGS--ESWFT 134

  Fly   239 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSK 272
            |.|..::.:.|.|..:.:|.||. |.:..||:|:
Mouse   135 DSNNAIASLAFHPTAQLLLIATA-NEIHFWDWSR 167

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdsNP_001245503.1 WD40 64..358 CDD:238121 49/164 (30%)
WD40 repeat 75..112 CDD:293791
WD40 repeat 118..154 CDD:293791 13/43 (30%)
WD40 repeat 159..195 CDD:293791 11/35 (31%)
WD40 repeat 202..237 CDD:293791 12/35 (34%)
WD40 repeat 244..280 CDD:293791 9/29 (31%)
WD40 repeat 288..325 CDD:293791
WD40 repeat 331..357 CDD:293791
Ambra1NP_766257.3 WD40 <48..>198 CDD:225201 37/124 (30%)
WD 1 51..90 11/38 (29%)
WD40 repeat 56..92 CDD:293791 11/35 (31%)
WD40 <59..198 CDD:295369 35/112 (31%)
WD 2 93..133 13/41 (32%)
WD40 repeat 99..135 CDD:293791 12/37 (32%)
WD 3 135..175 11/34 (32%)
WD40 repeat 140..176 CDD:293791 9/29 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 254..285
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 344..406
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 458..495
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 539..562
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 591..691
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 748..797
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1061..1080
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1113..1145
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1191..1300
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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