DRSC/TRiP Functional Genomics Resources

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Protein Alignment wds and Tbl3

DIOPT Version :9

Sequence 1:NP_001245503.1 Gene:wds / 53428 FlyBaseID:FBgn0040066 Length:361 Species:Drosophila melanogaster
Sequence 2:NP_663371.2 Gene:Tbl3 / 213773 MGIID:2384863 Length:801 Species:Mus musculus


Alignment Length:343 Identity:84/343 - (24%)
Similarity:140/343 - (40%) Gaps:66/343 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 VSAVKFSPNGEWLASSSADKLIKIWGAYDG---KFEKTISGHKLGISDVAWSSDSRLLVSGSDDK 136
            :::...||:.|.|.::|...|:..|...:|   :..|.|  |...::.:|:.:.|.||.:|..|.
Mouse    69 ITSFDLSPDDEVLVTASRALLLAQWAWREGTVTRLWKAI--HTAPVASMAFDATSTLLATGGCDG 131

  Fly   137 TLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSN--LIVSGSFDESVRIWDVRTGKCLKTLPAHSD 199
            .::||::.........:|....|....|:|...  |:.|.:.|.|:|:|.::...||..|.||..
Mouse   132 AVRVWDIVQHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSAVDTSIRVWSLQDRSCLAVLTAHYS 196

  Fly   200 PVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKT-----------LIDDDNPPVSFVKFSPNG 253
            .|:::.|:..|..::||..|.:|.:||..|.|..:|           |:.:...|...||.|  |
Mouse   197 AVTSLSFSEGGHTMLSSGRDKICIVWDLQSYQTTRTVPVFESVEASVLLPEQPAPALGVKSS--G 259

  Fly   254 KYILAATLDNTLKLWDYSKGKCLKT----------------------------------YTGHKN 284
            .:.|.|.....|::|:.:.|:|:.|                                  |..|..
Mouse   260 LHFLTAGDQGILRVWEAASGQCVYTQPQMPGLRQELTHCTLARAADLLLTVTADHNLLLYEAHSL 324

  Fly   285 EKYCIFANFSV---------TGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTE 340
            :....||.:|.         .....||..|....:.::.||:. ..|.|.||||.||........
Mouse   325 QLQKQFAGYSEEVLDVRFLGPSDSHIVVASNSPCLKVFELQTL-ACQILHGHTDIVLALDVFRKG 388

  Fly   341 NIIASAALENDKTIKLWK 358
            .:.||.|  .|::|::||
Mouse   389 WLFASCA--KDQSIRIWK 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdsNP_001245503.1 WD40 64..358 CDD:238121 82/341 (24%)
WD40 repeat 75..112 CDD:293791 10/39 (26%)
WD40 repeat 118..154 CDD:293791 8/35 (23%)
WD40 repeat 159..195 CDD:293791 11/37 (30%)
WD40 repeat 202..237 CDD:293791 11/45 (24%)
WD40 repeat 244..280 CDD:293791 11/69 (16%)
WD40 repeat 288..325 CDD:293791 9/45 (20%)
WD40 repeat 331..357 CDD:293791 7/25 (28%)
Tbl3NP_663371.2 WD40 60..602 CDD:225201 84/343 (24%)
WD 1 64..105 8/35 (23%)
WD40 repeat 69..105 CDD:293791 8/35 (23%)
WD 2 107..146 10/40 (25%)
WD40 <108..137 CDD:197651 8/28 (29%)
WD40 repeat 112..149 CDD:293791 8/36 (22%)
WD40 144..449 CDD:238121 65/266 (24%)
WD 3 149..190 12/40 (30%)
WD40 repeat 155..193 CDD:293791 11/37 (30%)
WD 4 193..232 13/38 (34%)
WD40 repeat 198..237 CDD:293791 12/38 (32%)
WD40 repeat 245..286 CDD:293791 12/42 (29%)
WD 5 245..284 11/40 (28%)
WD 6 290..329 2/38 (5%)
WD40 328..633 CDD:238121 23/80 (29%)
WD 7 332..372 7/40 (18%)
WD40 repeat 338..374 CDD:293791 7/36 (19%)
WD 8 374..413 13/33 (39%)
WD40 repeat 379..418 CDD:293791 9/28 (32%)
WD 9 419..459
WD40 repeat 426..476 CDD:293791
WD 10 477..516
WD40 repeat 482..518 CDD:293791
WD 11 519..560
WD40 repeat 524..560 CDD:293791
WD 12 562..602
WD40 repeat 566..590 CDD:293791
WD 13 604..642
WD40 repeat 608..634 CDD:293791
Utp13 654..788 CDD:285789
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1422
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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