Protein Alignment wds and gldi-1

DIOPT Version :10

• Sequence 1: NP_524984.1
• Gene: wds / 53428
• FlyBaseID: FBgn0040066
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_493745.1
• Gene: gldi-1 / 173439
• WormBaseID: WBGene00021074
• Length: 473
• Species: Caenorhabditis elegans
• Alignment Length: 391
• Identity: 97/391 - (24%)
• Similarity: 158/391 - (40%)
• Gaps: 99/391 - (25%)

  Fly    58 VKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFE---KTISGHKLGISD 119
            |:|......::.||.:.|.:.:|||:|..|||.|.|:.::||   |.:.|   .|...||..:..
 Worm    91 VRPVTRCSASIPGHGEPVISAQFSPDGRGLASGSGDQTMRIW---DIELELPLHTCKSHKSWVLC 152

  Fly   120 VAWSSDSRLLVSGSDDKTLKVWELSTGKSL-KTLKGHSNYVFCCNF-----NPQSNLIVSGSFDE 178
            :|||.|:..:.|...:..:.:|...||:.: ||||.|..::....:     :|...|:.|...|.
 Worm   153 IAWSPDATKIASACKNGEICIWNAKTGEQIGKTLKRHKQWITSLAWQPMHKDPTCRLLASCGKDG 217

  Fly   179 SVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG------------- 230
            ::.|||...|..::.|..|:..|:.:.:..:| ||.|.|.|...::|....|
 Worm   218 NIFIWDTVQGTVVRCLSGHTASVTCLRWGGEG-LIYSGSQDRTVKMWRADDGVMCRNMTGHAHWI 281

  Fly   231 --------------------QCLK-------------------------TLI--DDD------NP 242
                                :|:|                         .|:  .||      ||
 Worm   282 NTLALNTDYALRTSCFEPSKRCIKPDTVEECQKVAQTRYEAALEIAGGERLVSGSDDFTLFMWNP 346

  Fly   243 P---------------VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFAN 292
            .               |:.|.|||:.:||.:|:.|.::|||....||.|.:..||....|.:..:
 Worm   347 KETKQSINRMTGHMQLVNQVVFSPDTRYIASASFDKSVKLWCGRTGKYLASLRGHVGPVYQVAWS 411

  Fly   293 FSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLW 357
               ...:.:||||.|:.:.::.|::|.:...|.||.|.|......|....:.|..  .||.:|||
 Worm   412 ---ADSRLLVSGSADSTLKVFELKTKSLYYDLPGHGDEVFTVDWSPEGTKVVSGG--KDKVLKLW 471

  Fly   358 K 358
            :
 Worm   472 R 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wds	NP_524984.1	WD40	<63..361	CDD:441893	95/386 (25%)
		WD40 repeat	75..112	CDD:293791	15/39 (38%)
		WD40 repeat	118..154	CDD:293791	11/36 (31%)
		WD40 repeat	159..195	CDD:293791	8/40 (20%)
		WD40 repeat	202..237	CDD:293791	10/92 (11%)
		WD40 repeat	244..280	CDD:293791	15/35 (43%)
		WD40 repeat	288..325	CDD:293791	7/36 (19%)
		WD40 repeat	331..357	CDD:293791	6/25 (24%)
gldi-1	NP_493745.1	NLE	7..70	CDD:462380
		WD40	95..472	CDD:441893	94/385 (24%)
		WD40 repeat	110..145	CDD:293791	14/37 (38%)
		WD40 repeat	150..188	CDD:293791	11/37 (30%)
		WD40 repeat	194..235	CDD:293791	9/40 (23%)
		WD40 repeat	240..275	CDD:293791	9/35 (26%)
		WD40 repeat	282..356	CDD:293791	7/73 (10%)
		WD40 repeat	363..399	CDD:293791	15/35 (43%)
		WD40 repeat	405..441	CDD:293791	8/38 (21%)
		WD40 repeat	447..471	CDD:293791	6/25 (24%)