DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wds and ambra1a

DIOPT Version :9

Sequence 1:	NP_001245503.1	Gene:	wds / 53428	FlyBaseID:	FBgn0040066	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	XP_002667715.3	Gene:	ambra1a / 100332642	ZFINID:	ZDB-GENE-111104-2	Length:	1344	Species:	Danio rerio

Alignment Length:	147	Identity:	40/147 - (27%)
Similarity:	75/147 - (51%)	Gaps:	8/147 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 VAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNP-QSNLIVSGSFDESVRIW 183
            :|:|.|..|:.|...:..:.:.|:.:||.:.:|.||....:|..|:| ...||.||..|..||||
Zfish    58 LAFSPDRSLMASTHVNHNIYITEVKSGKCVHSLVGHRRTPWCLTFHPIIPGLIASGCLDGEVRIW 122

  Fly   184 DVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ---CLKTLIDDDNPPVS 245
            |:..|. ...|...:..::::.|:....|::.::.:.: .:||.:..:   .:||..:.:.  |.
Zfish   123 DLHGGS-ESWLTESNSAIASLAFHPTAQLLLIATNNEV-HLWDWSRKEPFTVVKTASETER--VR 183

  Fly   246 FVKFSPNGKYILAATLD 262
            .|:|.|.|.|:|.|.::
Zfish   184 LVRFDPLGHYLLTAIVN 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wds	NP_001245503.1	WD40	64..358	CDD:238121	40/147 (27%)
		WD40 repeat	75..112	CDD:293791
		WD40 repeat	118..154	CDD:293791	9/33 (27%)
		WD40 repeat	159..195	CDD:293791	14/36 (39%)
		WD40 repeat	202..237	CDD:293791	6/37 (16%)
		WD40 repeat	244..280	CDD:293791	8/19 (42%)
		WD40 repeat	288..325	CDD:293791
		WD40 repeat	331..357	CDD:293791
ambra1a	XP_002667715.3	WD40	<43..>197	CDD:225201	39/142 (27%)
		WD40	<58..197	CDD:295369	39/142 (27%)
		WD40 repeat	58..91	CDD:293791	8/32 (25%)
		WD40 repeat	98..134	CDD:293791	15/36 (42%)
		WD40 repeat	139..175	CDD:293791	4/36 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0266
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900