Protein Alignment ACXB and Gyc76C

DIOPT Version :9

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_001163473.1
• Gene: Gyc76C / 8674026
• FlyBaseID: FBgn0266136
• Length: 1525
• Species: Drosophila melanogaster
• Alignment Length: 1179
• Identity: 209/1179 - (17%)
• Similarity: 396/1179 - (33%)
• Gaps: 478/1179 - (40%)

  Fly   160 LPIPSIRGAALLATSVSLMYIGLFIYFLKSDDEDISEVVHDLDTICVDIFHYLGFNLMGIFFR-- 222
            :|:.|.:.|...|:::..        |.:::..| ::||..|    :.:..|..:|...|.:.
  Fly   117 IPMISYKCAEYRASAIPT--------FARTEPPD-TQVVKSL----LALLRYYAWNKFSILYEDV 168

  Fly   223 ------IMNDTMV--------RSSFLDRHQFLKEEM--------WLRQARQQESMLLDSILPPQI 265
                  ::.|...        :.||:|......|:|        |.                 |:
  Fly   169 WSPVADLLKDQATKRNMTINHKQSFIDNRVKCCEQMLDCCRSGYWY-----------------QL 216

  Fly   266 AKPIQQSIKERIMLSETDSDRIVVNARRTENFMAIQIHPDVSILYADVVNYTHLTTTLTVEKLVK 330
            .:......:..:.|...:|....:::..|....|   ..:..:::.|::.|:.    ...||.::
  Fly   217 VQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFA---RGEYMVIFVDMMVYSE----REAEKYLR 274

  Fly   331 VLHDLYGRFDMAASTFKVQRIKFLGDCYYCVAGLGEADPDHARMAVSL-----------GISMIA 384
                            :|.:|.|:.:|:        :..:..:||.||           .|....
  Fly   275 ----------------RVDQITFMSNCH--------STENFNQMARSLLVVASTPPTKDYIQFTK 315

  Fly   385 NIQEVRAHRALDIDM-RIGVHSG-----TLLAGVIGQAKLQYDIWGPDVDIANRLEATGKPGYVH 443
            .:|:..:....:::: |:.|.|.     ::.|..:..:...| .|.  ||...|.|
  Fly   316 QVQKYSSKPPFNLEIPRLFVESNFSKFISIYAAYLYDSVKLY-AWA--VDKMLREE--------- 368

  Fly   444 VSGRTLSSLNVAEYTVFPGTEVAQSDPILQKQPMTTYLLTAAPSRNSVRSVDAV---HSY----- 500
                               |.|...|.|.:            .:.|..|.:|.:   .:|
  Fly   369 -------------------TRVLTDDVIFE------------VASNGTRVIDTIIKNRTYMSITG 402

  Fly   501 AEIDINALGASRKSPILRPTLMSDELREEFKKMPVGGFNIRS--PCCRDNSNDEKVNHGLGMFCV 563
            ::|.|:..|.|.                       |.|::.:  |...:|||:...|:.:
  Fly   403 SKIKIDQYGDSE-----------------------GNFSVLAYKPHKWNNSNNMPCNYHM----- 439

  Fly   564 AFKDSSLEWSYLHKPDFILKYSVL---LAWGIG--------CCLIYIQIV---NDKFTICVECIV 614
                  :..:|.|:.:...:|.::   :.|..|        .|....::.   :..:|..|..:|
  Fly   440 ------VPVAYFHQGEEHPEYKLINGSIDWPSGGEKPADEPMCGFANELCKKDDTHYTSTVAAVV 498

  Fly   615 IDMVVFTFLTSLLFISWFKKVCW----------WRCVENDSRKY--------------------- 648
            :.  |..|.:.::.:|.::|  |          |:...|:.:.|
  Fly   499 LG--VLLFCSGVITMSIYRK--WKIELEIEGLLWKIDPNEIKGYSGNEIVSSPSKVSLMSAQSYG 559

  Fly   649 -----------GRVSCKLFKIWE---------------------RIQH----SF---------VL 668
                       ||:...:.:|.|                     .::|    ||         :|
  Fly   560 SRWTNQFVTSTGRLRGAVVRIKELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASVEPTRIL 624

  Fly   669 RVTIYMSIVASYY------------LLISTILLNCDKNQYELDVINSKL-YHYDIVTDNCF--NP 718
            .||.|.: ..|.|            |.|::::.:..|..  :.:.||:| ||.::.:.||.  :.
  Fly   625 LVTDYCA-KGSLYDIIENEDIKLDDLFIASLIHDLIKGM--IYIHNSQLVYHGNLKSSNCVVTSR 686

  Fly   719 WVF--TDMISLIVGVSYTFARIPFALKMLITCCA------------------------------- 750
            |:.  ||                |.|..|..|..
  Fly   687 WMLQVTD----------------FGLHELRQCAENESIGEHQHYRNQLWRAPELLRNHIHGSQKG 735

  Fly   751 -TVAYLVIVFFQYS-------FIFEHSATT-----------TPF-------MKAE-----LAHCL 784
             ..|:.:|::..:|       ..||.....           .||       ::||     :..|:
  Fly   736 DVYAFAIIMYEIFSRKGPFGQINFEPKEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACI 800

  Fly   785 RVCMMLLTMYAK--ERQSEFNT-----------KINFKINQDLQGKQKAAD-----ITNKSIII- 830
            |.|      :|:  |.:.||:.           |....::|.::..:|.|:     :|.::.::
  Fly   801 RDC------WAEDPEERPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLC 859

  Fly   831 --------LLTNILPSHVVEVY-----LDSVANHELYYENYKMVSVMFAMLINF------QMDLP 876
                    ||..:||..|.|..     ::.|        :|.:|::.|:.::.|      ...|.
  Fly   860 EEKMKTEDLLHRMLPQSVAEKLTMGQGVEPV--------SYDLVTIYFSDIVGFTAMSAESTPLQ 916

  Fly   877 SLRVLNDIITEFDRLLNAYKEYYVVEKIKVVGCTYMAACGLDFTLAKSKFGSRTHASYSSELEQV 941
            .:..|||:.|.|||::..|..|    |::.:|..||...||..     |.|.| ||.
  Fly   917 VVNFLNDLYTVFDRIIRGYDVY----KVETIGDAYMVVSGLPI-----KNGDR-HAG-------- 963

  Fly   942 LYRKESKGTENDHDEVAFIMTTFALDLMRVLSVCNKAYAGRPFDRALSTGEICIGISTGEIMAGV 1006
                          |:|    :.||:|:.  :|.....|.||.:    |.::.||:.||.::|||
  Fly   964 --------------EIA----SMALELLH--AVKQHRIAHRPNE----TLKLRIGMHTGPVVAGV 1004

  Fly  1007 VGASQPHYDIWGNPVNMASRMESTGLPGHIHVTQETANILEQF--DIMCMYRGMTFVKGRGEIPT 1069
            ||.:.|.|.::|:.||.||||||.|....||::.:....|::.  ..:...||:..:||:|::.|
  Fly  1005 VGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVT 1069

  Fly  1070 YFV-GIDDN 1077
            ::: |.::|
  Fly  1070 WWLTGANEN 1078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AC_N	<36..276	CDD:292831	20/139 (14%)
		CYCc	249..459	CDD:214485	29/226 (13%)
		Nucleotidyl_cyc_III	298..484	CDD:299850	29/202 (14%)
		CYCc	825..1047	CDD:214485	65/241 (27%)
		Nucleotidyl_cyc_III	853..1072	CDD:299850	65/226 (29%)
Gyc76C	NP_001163473.1	PBP1_Speract_GC_like	26..445	CDD:107365	67/465 (14%)
		ANF_receptor	48..412	CDD:279440	58/398 (15%)
		PK_GC-A_B	543..827	CDD:270944	46/308 (15%)
		HNOBA	<835..881	CDD:285003	10/45 (22%)
		CYCc	860..1052	CDD:214485	66/241 (27%)
		Guanylate_cyc	887..1074	CDD:278633	66/236 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454001
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830