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Protein Alignment ACXB and CYR1

DIOPT Version :9

Sequence 1:	NP_620474.2	Gene:	ACXB / 53427	FlyBaseID:	FBgn0040509	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	NP_012529.3	Gene:	CYR1 / 853452	SGDID:	S000003542	Length:	2026	Species:	Saccharomyces cerevisiae

Alignment Length:	806	Identity:	142/806 - (17%)
Similarity:	258/806 - (32%)	Gaps:	246/806 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   295 ENFMAIQIHPDVSILYADVVNY--THLTTTLTVEKLVKVLHDLYGRFDMAASTFKVQRIKFLGDC 357
            :|...:.:..:..:.|.:|:||  ..|...|:..|:..:.........:|.......::.|:||
Yeast   909 KNLQLLDLSSNKFMHYPEVINYCTNLLQIDLSYNKIQSLPQSTKYLVKLAKMNLSHNKLNFIGD- 972

  Fly   358 YYCVAGLGEADPDHARMAVSLGISMIANIQEVRAHRALDI---DMRIGVHSGTLLAGVIGQAKLQ 419
                  |.|...   ...::|..:.|::| :..|....::   |.||.....||       .||:
Yeast   973 ------LSEMTD---LRTLNLRYNRISSI-KTNASNLQNLFLTDNRISNFEDTL-------PKLR 1020

  Fly   420 YDIWGPDVDIANRLEATGKPGYVHVS-------GRTLSSLNVAEYTVFPGTEVAQSDPILQKQPM 477
                        .||....| ...:|       ..|..:||.|:.:..|| |:......|:|..:
Yeast  1021 ------------ALEIQENP-ITSISFKDFYPKNMTSLTLNKAQLSSIPG-ELLTKLSFLEKLEL 1071

  Fly   478 TTYLLTAAP--------------SRNSVRSVDAVHSYAEIDINALGASRKSPILRPTLMSDELRE 528
            ....||..|              :||.:       .|...:::.|.:.|..     .|.|:.:|:
Yeast  1072 NQNNLTRLPQEISKLTKLVFLSVARNKL-------EYIPPELSQLKSLRTL-----DLHSNNIRD 1124

  Fly   529 EFKKMPVGGFNIRSPCCRDNSNDEKVNHGLGMFCVAFKDSSLEWSYLHKPDFILKYSVLL----- 588
            ....|.    |:.......:||             ||.:||||.|:.|...:..|.|..|
Yeast  1125 FVDGME----NLELTSLNISSN-------------AFGNSSLENSFYHNMSYGSKLSKSLMFFIA 1172

  Fly   589 --------AWGIGCCLIYIQIVN---DKFTICVECIVIDMVVFTFLTSLLFISWFKKVCWWRCVE 642
                    .|.:..|.:.::::|   :.|: .|..:.::.:...:|:
Yeast  1173 ADNQFDDAMWPLFNCFVNLKVLNLSYNNFS-DVSHMKLESITELYLS------------------ 1218

  Fly   643 NDSRKYGRVSCKLFKIWERIQHSFVLRVTIYMSIVASYYLLISTILLNCDKNQYELDVINSKLYH 707
              ..|...:|......|..:: :.:|.....:|:.|....|....:.:...||.:.::.|   ||
Yeast  1219 --GNKLTTLSGDTVLKWSSLK-TLMLNSNQMLSLPAELSNLSQLSVFDVGANQLKYNISN---YH 1277

  Fly   708 YDIVTDNCFNPW----------------------------VFTDMISL----------IVGVSYT 734
            ||         |                            :..|:..|          ::.|:..
Yeast  1278 YD---------WNWRNNKELKYLNFSGNRRFEIKSFISHDIDADLSDLTVLPQLKVLGLMDVTLN 1333

  Fly   735 FARIP-----FALKMLITCCATVAYLVI-VFFQYSFIFEHSATTTPF----------------MK 777
            ..::|     |.|:...:....:.|.|. ...|..::.....|...|                ..
Yeast  1334 TTKVPDENVNFRLRTTASIINGMRYGVADTLGQRDYVSSRDVTFERFRGNDDECLLCLHDSKNQN 1398

  Fly   778 AELAHCL---------RVCMMLLTMYAKERQSEFNTKINF---KINQDLQGK----QKAADITNK 826
            |:..|.:         ::.:..|..|..|......|.:.|   ::|:::.|.    ...||:.|.
Yeast  1399 ADYGHNISRIVRDIYDKILIRQLERYGDETDDNIKTALRFSFLQLNKEINGMLNSVDNGADVANL 1463

  Fly   827 SIIILLTNILPSHVVEVYLDSVANHELYYENYKMVSVMFAMLINFQMDLPSLRVLNDIITEFDRL 891
            |...||:             ...:..:|....|    :||..:...|.:.| :...|..|...:.
Yeast  1464 SYADLLS-------------GACSTVIYIRGKK----LFAANLGDCMAILS-KNNGDYQTLTKQH 1510

  Fly   892 LNAYKEYYVVEKIKVVGCTYMAACGLDFTLAKSK----FGSRTHASYSSELEQVLYRKESKGTEN 952
            |...:|.|  |:|::.| .|:....||..:..|:    |....|...|.::..|...|.
Yeast  1511 LPTKREEY--ERIRISG-GYVNNGKLDGVVDVSRAVGFFDLLPHIHASPDISVVTLTKA------ 1566

  Fly   953 DHDEVAFIMTTFALDLMRVLSVCNKA 978
              ||:..:.|....:.|.|.:||:.|
Yeast  1567 --DEMLIVATHKLWEYMDVDTVCDIA 1590

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.