DRSC/TRiP Functional Genomics Resources

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Protein Alignment ACXB and Gucy1a2

DIOPT Version :9

Sequence 1:NP_620474.2 Gene:ACXB / 53427 FlyBaseID:FBgn0040509 Length:1114 Species:Drosophila melanogaster
Sequence 2:NP_076446.1 Gene:Gucy1a2 / 66012 RGDID:621655 Length:730 Species:Rattus norvegicus


Alignment Length:314 Identity:79/314 - (25%)
Similarity:139/314 - (44%) Gaps:63/314 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   237 HQFLKEEMWLRQARQQESMLLDSILPPQIAKPIQQSIKERIMLSETDSDRIVVNARRTENFMAIQ 301
            ||.|:||      :::...||.||.|..:|:.:.|              |..|.||:.:      
  Rat   478 HQALEEE------KKKTVDLLYSIFPGDVAQQLWQ--------------RQQVQARKFD------ 516

  Fly   302 IHPDVSILYADVVNYTHLTTTLTVEKLVKVLHDLYGRFDMAASTFKVQRIKFLGDCYYCVAGLGE 366
               ||::|::|:|.:|.:....|..:::.:|::||.|||.......:.:::.:||.|...:||..
  Rat   517 ---DVTMLFSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGFLDIYKVETIGDAYCVASGLHR 578

  Fly   367 ADPDHARMAVSLGISMIANIQEVRAHRALDIDMRIGVHSGTLLAGVIGQAKLQYDIWGPDVDIAN 431
            ....||:....:.:.|:...:||.......|.||||:|||::||||:|....:|.::|.:|.:|:
  Rat   579 KSLCHAKPIALMALKMMELSEEVLTPDGRPIQMRIGIHSGSVLAGVVGVRMPRYCLFGNNVTLAS 643

  Fly   432 RLEATGKPGYVHVSGRTLSSLNVAE-YTVFPGTEVAQSDPILQKQPMTTYLLTAAPSRNSVRSVD 495
            :.|:...|..:::|..|...|...: :|..|.:.....|...::.|...|.|             
  Rat   644 KFESGSHPRRINISPTTYQLLKREDSFTFIPRSREELPDNFPKEIPGVCYFL------------- 695

  Fly   496 AVHSYAEIDINALGASRKSPILRPTLMSDELREEFKKMPVGGFNIRSPCCRDNS 549
                       .|....|.|  :|:|.|..:    ||:   .:||.:...|:.|
  Rat   696 -----------ELRTGPKPP--KPSLSSSRI----KKV---SYNIGTMFLRETS 729

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ACXBNP_620474.2 AC_N <36..276 CDD:292831 12/38 (32%)
CYCc 249..459 CDD:214485 56/210 (27%)
Nucleotidyl_cyc_III 298..484 CDD:299850 51/186 (27%)
CYCc 825..1047 CDD:214485
Nucleotidyl_cyc_III 853..1072 CDD:299850
Gucy1a2NP_076446.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..53
HNOB <157..268 CDD:285002
HNOBA 314..501 CDD:285003 10/28 (36%)
CYCc 483..672 CDD:214485 58/217 (27%)
Guanylate_cyc 512..696 CDD:278633 53/216 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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