Protein Alignment ACXB and si:dkey-206f10.1

DIOPT Version :10

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: XP_009293230.1
• Gene: si:dkey-206f10.1 / 560719
• ZFINID: ZDB-GENE-041014-154
• Length: 1187
• Species: Danio rerio
• Alignment Length: 1124
• Identity: 289/1124 - (25%)
• Similarity: 499/1124 - (44%)
• Gaps: 247/1124 - (21%)

  Fly    47 LMISYLTVFFPLFIFVVVGCELCPWIF----SEQKKLIYYESLTAIVVLVAVPGILSINFFESFV 107
            :::|:.|.|     |:.....||..:.    |...|.::|..:.:
Zfish   188 ILMSWFTGF-----FMACAIALCVLVLTCKRSHSPKWLHYAGMAS-------------------- 227

  Fly   108 LRHRWIMVFSSILSAYIVVLVDIFQILVFHFK--YHWPLNTLYDVFVLCMIYMFLPIPSI--RGA 168
                |:...:.:|..           |.:..:  ..|     |.:|.|...|..||:|.:  .||
Zfish   228 ----WLSQTAQVLGG-----------LAYGLERDQSW-----YVLFTLFATYTLLPLPLLWAIGA 272

  Fly   169 ALLATSVSLMYIGLFIYFLKSDDEDISEVVHDLDTICVDIFH--------YLGFNLMGIFFRIMN 225
            ..| ||:        ::........|||         |.:|.        |...|:.|:|...:.
Zfish   273 GTL-TSI--------LHLTAETIRHISE---------VGLFRKLLAKALLYTSMNVAGLFIHYLT 319

  Fly   226 DTMVRSSFLDRHQFLKEEMWLRQARQQESMLLDSILPPQIAKPIQQSIKERIMLSETDS--DRIV 288
            |...|.:||:..:.::..|.|....|::..|:.||||..:|..         |:|:..|  |.:
Zfish   320 DRSQRQAFLETRRCIEGRMKLETENQRQERLVLSILPRFVALE---------MISDMTSMDDEL- 374

  Fly   289 VNARRTENFMAIQIH--PDVSILYADVVNYTHLTTTLTVEKLVKVLHDLYGRFDMAASTFKVQRI 351
                ..:.|..:.||  .|||||:||:..:|.|:..::.::||::|::|:||||..|..:...||
Zfish   375 ----DPQQFHKVYIHQYKDVSILFADIKGFTLLSMNMSAQELVRLLNELFGRFDRLAEEYDCLRI 435

  Fly   352 KFLGDCYYCVAGLGEADPDHARMAVSLGISMIANIQEVRAHRALDIDMRIGVHSGTLLAGVIGQA 416
            |.||||||||:|:.|....|||..|.:|::||:.::.:|..:..|:|||||:|:|::|.||:|..
Zfish   436 KILGDCYYCVSGVPEPQRAHARCCVEMGLAMISTMRSLRKQQNFDMDMRIGIHTGSVLCGVLGLQ 500

  Fly   417 KLQYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSLNVAEYTVFPGTEVAQSDPILQKQPMTTYL 481
            |.|:|:|..||.|||.|||.|.||.:|:|..||..|: ..:....|....::: .|:|..:.|:|
Zfish   501 KWQFDVWSWDVGIANMLEAGGIPGRIHISRATLDCLD-GSFQTEDGRGYERNE-FLRKHNIDTFL 563

  Fly   482 LTAAPSRNSVRSVDAVHSYAEIDINALGASRKSPILRPTLMSDELREEFK-----KMPVGGFNIR 541
            :                .:.|.|:|.:.|............:.|:...|.     ::|.
Zfish   564 I----------------CHKEDDLNEMEAEHPKTRHNNRPWNKEILASFSNGSYTQLPT------ 606

  Fly   542 SPCCRDNSND--EKVNHGLGM-------------FCVAFKDSSLEWSYLHKPDFILKYSVLLAWG 591
            |..||..|.:  :::.|.:.:             ..:.|||:.:|..:....|.:.|.:::
Zfish   607 SSACRSMSKEINKRIEHAIDLRSSERMRQEHITPVTLVFKDAHIEEKFSQVRDEMFKTNLV---- 667

  Fly   592 IGCCLIYIQIVNDKFTICVECI--VIDMVVFTFLTSLLFISWFKKVCWWRCVENDSRKYGRVSCK 654
              |..|.:.::     :.|:.:  |..|.::|.|...||:..:..:......|......|.:  :
Zfish   668 --CSFIMLLLL-----MAVQALIPVPRMYLWTVLQFCLFLLGYLLLLVMVLAEEFKHSPGVL--Q 723

  Fly   655 LFKIWERIQHSFVLRVTIYMSIVASYYLLISTILLNCDKNQYELDVINSKLYHYDIVTDN----- 714
            .|..|  |..:..:|..:.::.:|..:.:....::.|  |..|:..|:::      .|:.
Zfish   724 QFCCW--IHENNSMRNLLTITAIAMNFGMALFDMMWC--NSSEMKEISTR------ETEGYKAGQ 778

  Fly   715 -----CFNPWVF--TDMISLIVGVSYTFARIPFALKM--LITCCATVAYLVIVFFQYSFIF--EH 768
                 |..|.||  :.::|::  ....|.|:...||:  |:...|...|.:.|.|...::.  ||
Zfish   779 KPLTACTYPEVFVLSGVVSMV--TCAVFLRMSSLLKLTILLFVVAVYTYFIEVSFHMLYVHQQEH 841

  Fly   769 S-ATTTPFMKAELAHCLRVCMMLLTMYAKERQSEFNTKINFKINQDLQGKQKAADITN--KSIII 830
            . .:.:.|::.:....|.:.|.::.:....|:.|..|:::|...  ||.:|:..::.:  :....
Zfish   842 EHLSRSHFLRRKGVSILLMAMFMIAVLYNGRRWEATTRLDFLWR--LQAQQEVQEMRDLREHNEC 904

  Fly   831 LLTNILPSHVVEVYLDSVAN-HELYYENYKMVSVMFAMLINF-----QMDL-----PSLRVLNDI 884
            ||.||||:||...:|:...| .|||.::|..|.||||.:..|     |.::     ..|::||:|
Zfish   905 LLHNILPAHVARHFLERNRNDQELYSQSYDEVGVMFASIAGFNDYYEQKEIKHEGVECLKLLNEI 969

  Fly   885 ITEFDRLLNAYKEYYV-VEKIKVVGCTYMAACGLDFTLAKSKFGSRTHASYSSELEQVLYRKESK 948
            |.:||.||.  :.|:: :||||.:|..||||.||                 |.:       |:|:
Zfish   970 IADFDELLE--ESYFLDIEKIKTIGSCYMAASGL-----------------SPD-------KQSR 1008

  Fly   949 GTENDHDEVAFIMTTFALDLMRVLSVCNKAYAGRPFDRALSTGEICIGISTGEIMAGVVGASQPH 1013
            ...:.|.....::  |||.:...|...||        .:::..::.:||:.|.::|||:||::|.
Zfish  1009 VVNDWHHLSELVL--FALAMQETLREINK--------HSMNNFQLRVGIAHGPVVAGVIGATKPQ 1063

  Fly  1014 YDIWGNPVNMASRMESTGLPGHIHVTQETANILEQFDIMCMYRGMTFVKG----RGEIPTYFVGI 1074
            |||||..||:||||:|||:.|.|.|.:.|.|||..:..:...||..::||    :|.:.|||:..
Zfish  1064 YDIWGMTVNLASRMDSTGVSGRIQVPEATRNILADWGFVLELRGEIYIKGVSERKGRVRTYFIST 1128

  Fly  1075 DDNLKFLPSNVKKNNMSKR 1093
            ...|      |..|.::.|
Zfish  1129 KRRL------VSSNGIADR 1141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AcyC	85..452	CDD:441717	115/382 (30%)
		Nucleotidyl_cyc_III	298..484	CDD:448371	78/187 (42%)
		Nucleotidyl_cyc_III	853..1072	CDD:448371	78/233 (33%)
si:dkey-206f10.1	XP_009293230.1	AC_N	<135..380	CDD:318454	51/268 (19%)
		Guanylate_cyc	382..564	CDD:425528	77/183 (42%)
		Adcy_cons_dom	<603..662	CDD:461877	11/64 (17%)
		Guanylate_cyc	928..1126	CDD:425528	78/233 (33%)