Protein Alignment ACXB and si:ch211-132f19.7

DIOPT Version :9

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: XP_688903.4
• Gene: si:ch211-132f19.7 / 560410
• ZFINID: ZDB-GENE-130530-619
• Length: 1183
• Species: Danio rerio
• Alignment Length: 1164
• Identity: 317/1164 - (27%)
• Similarity: 529/1164 - (45%)
• Gaps: 238/1164 - (20%)

  Fly    27 LKAKCKELCLEEEYKKYQ---------IRLMISYLTVFFPLFIFVVVGCELCP----WIFSEQKK 78
            |..|.|...||..|:::.         :..:|..||....:||::.:..|:..    |:..   .
Zfish   130 LHHKFKSHDLEHLYQQHSSGQRRTSLVVTNVIDILTKLHIIFIYLALAPEMVDSQHGWLAG---L 191

  Fly    79 LIYYESLTAIVVLVAVPGILSINFFESFVLRHRWIMVFSSILSAYIVVLVDIFQILVFHFK--YH 141
            |:...::..::||.. .|::|.::     ||:       :.|::::...|.....||:..:  ..
Zfish   192 LMALGAIICVLVLTC-KGLMSPDY-----LRY-------AGLASWLSQTVQALGGLVYGLETDQS 243

  Fly   142 WPLNTLYDVFVLCMIYMFLPIPSIRGAALLATSVSLMY----IGLFIYFLKSDDEDISEVVHDLD 202
            |     |.:|.|..||..||:|       |..|:.:.:    :.||:...|:.::  :.:|..|
Zfish   244 W-----YVLFTLFAIYTLLPLP-------LLWSICMGFLTAALHLFVDTFKNYND--TAIVRKL- 293

  Fly   203 TICVDIFHYLGFNLMGIFFRIMNDTMVRSSFLDRHQFLKEEMWLRQARQQESMLLDSILPPQIAK 267
             :...:. |:|.|..|:|...::|...|.:||:..:.::..:.:.:..|::..|:.||||
Zfish   294 -LAKGLL-YMGMNTAGLFIHYLSDRAQRQAFLETRRCIEGRVKMERENQRQERLVMSILP----- 351

  Fly   268 PIQQSIKERIMLSETDSDRIVVNARRTENFMAIQIH-------PDVSILYADVVNYTHLTTTLTV 325
                    |.:..|...|...::    :..:..|.|       .|||||:||:..:|.|:.|:..
Zfish   352 --------RFIAMEMIGDMTALD----DELLPQQFHKTYFHQYKDVSILFADIKGFTSLSMTMPA 404

  Fly   326 EKLVKVLHDLYGRFDMAASTFKVQRIKFLGDCYYCVAGLGEADPDHARMAVSLGISMIANIQEVR 390
            ::||:.|::|:||||..|......|||.||||||||:|:.|....|||..|.:|::||..|:.||
Zfish   405 QELVRTLNELFGRFDRLAEENHCMRIKILGDCYYCVSGVPEPQTAHARCCVEMGLAMINTIRYVR 469

  Fly   391 AHRALDIDMRIGVHSGTLLAGVIGQAKLQYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSL-NV 454
            .....|:|||||:|||::|.||:|..|.|:|:|..|||:||.|||.|.||.:|:|..||..| .|
Zfish   470 KELKRDMDMRIGIHSGSVLCGVLGLQKWQFDVWSWDVDVANMLEAGGIPGRIHISRATLDCLEGV 534

  Fly   455 AEYTVFPGTEVAQSDPILQKQPMTTYLLTAAPSRN----SVR--SVDAVHSYAEIDI-NALGA-- 510
            .|.....|.|   .:..|:|..:.|:|:...|..:    .||  |.|.....||:.. |.:|.
Zfish   535 YETEEGRGHE---RNEFLRKHKIDTFLIRHTPQDDKEPPKVRRTSKDETTWSAELPFDNIIGMNC 596

  Fly   511 -----SRKSPILRPTLM------SDELREEFKKMPVGGFNIRSPCCRDNSNDEKVNHGLGMFCVA 564
                 :..|.:..|..:      |.|:.:..|:    ...:||      |...:..| :..|.:.
Zfish   597 ILATFTNGSLVHLPNQITPHCAGSREINKRIKQ----AIEVRS------SERMRKEH-ITPFTLV 650

  Fly   565 FKDSSLEWSYLHKPDFILKYSVLLAWGIGCCLIYIQ-----IVNDKFTICVECIVIDMVVFTFLT 624
            |||:.:|..:....|.:.|.::..::   ..|::|.     |.:.:|.    .::|..:||.|:.
Zfish   651 FKDTHIEGKFSQMRDEMFKSNLACSF---LLLLFIMAAQALIPSPQFF----PMIIQFLVFLFVY 708

  Fly   625 SLLFI-----------SWFKKVCWWRCVENDSRKYGRVSCKLFKIWERIQHSFVLRVTIYMSIVA 678
            .|:.:           .:.:.:|.|                       |..:..:|..:.::.:|
Zfish   709 MLVLLVTLAEEFKRSPPYLQHLCCW-----------------------IHETKSIRNLLTLTAIA 750

  Fly   679 SYYLLISTILLNCDKNQYELDVINSKLYHYDIVTDN-CFNP--WVFTDMISLIVGVSYTFARIPF 740
            ..:.:.|..:..|:....|.:..|....|......| |.:|  :|.:.:::::  ....|.|:..
Zfish   751 INFGVASCNIFWCNGTFEETEKSNKNSEHGKQWPVNICTHPEFFVLSGVVAMV--TCAVFLRLSC 813

  Fly   741 ALKM--LITCCATVAYLVIVFFQYSFIFEHSAT---TTPFMKAELAHCLRVCMMLLTMYAKERQS 800
            .||:  |....|...||:.|.|...||.:|..:   .:.:::.:....|.:.|.::.:....||.
Zfish   814 LLKLAVLTLVIAVYTYLIEVAFHVLFIRQHQNSQIQRSQYLRRKGISVLLMAMFVVVVLYNSRQL 878

  Fly   801 EFNTKINFKINQDLQGKQKAADIT-----NKSIIILLTNILPSHVVEVYLDSVANHE-LYYENYK 859
            |..::::|...  ||.:|:..|:.     |:   .||.||||:||...:|:...|:| |:.|:|:
Zfish   879 ETTSRLDFLWR--LQARQEVEDMKELREHNE---CLLYNILPAHVARHFLERDRNNEDLFSESYE 938

  Fly   860 MVSVMFAMLINF----------QMDLPSLRVLNDIITEFDRLLNAYKEYYV-VEKIKVVGCTYMA 913
            .|.||||.:..|          ..|:..||:||:||.:||.||:  :.|:. :||||.:|..|||
Zfish   939 RVGVMFASIPGFSDYYEKKELIHQDVECLRLLNEIIADFDELLD--EPYFQDIEKIKTIGSCYMA 1001

  Fly   914 ACGLDFTLAKSKFGSRTHASYSSELEQVLYRKESKGTENDHDEVAFIMT--TFALDLMRVLSVCN 976
            |.||                 |.|.::.            .||.|.:.|  .|||.:...|...|
Zfish  1002 ASGL-----------------SPEKQEC------------EDEWAHLSTLVLFALAMQETLKEIN 1037

  Fly   977 KAYAGRPFDRALSTGEICIGISTGEIMAGVVGASQPHYDIWGNPVNMASRMESTGLPGHIHVTQE 1041
            |        |..:...:.:|||.|.::|||:||::|.|||||..||:||||:||||.|.|.|.:.
Zfish  1038 K--------RTSNDFWLRVGISHGPVVAGVIGATKPQYDIWGMTVNLASRMDSTGLSGRIQVPEA 1094

  Fly  1042 TANILEQFDIMCMYRGMTFVKG----RGEIPTYFVGIDDNLKFLPSNVKKNNMSKRFSI 1096
            |:.:|.:...|...||..:|||    ||.:.||||...::    .|:..:.|.|:..|:
Zfish  1095 TSRVLAEHGFMLQLRGEIYVKGVSERRGAVRTYFVSSREH----NSSYAERNTSRGISL 1149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AC_N	<36..276	CDD:292831	52/258 (20%)
		CYCc	249..459	CDD:214485	88/217 (41%)
		Nucleotidyl_cyc_III	298..484	CDD:299850	85/193 (44%)
		CYCc	825..1047	CDD:214485	86/235 (37%)
		Nucleotidyl_cyc_III	853..1072	CDD:299850	85/235 (36%)
si:ch211-132f19.7	XP_688903.4	AC_N	<133..375	CDD:292831	58/291 (20%)
		CYCc	338..537	CDD:214485	87/215 (40%)
		Guanylate_cyc	381..559	CDD:278633	82/180 (46%)
		DUF1053	579..667	CDD:283888	19/98 (19%)
		CYCc	903..1103	CDD:214485	87/241 (36%)
		Guanylate_cyc	932..1131	CDD:278633	87/237 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810