DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXB and npr1b

DIOPT Version :9

Sequence 1:	NP_620474.2	Gene:	ACXB / 53427	FlyBaseID:	FBgn0040509	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	XP_009290669.2	Gene:	npr1b / 555911	ZFINID:	ZDB-GENE-100805-4	Length:	1070	Species:	Danio rerio

Alignment Length:	269	Identity:	75/269 - (27%)
Similarity:	134/269 - (49%)	Gaps:	28/269 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 DRHQFLKEEMWLR-QARQQESMLLDSILP--PQIAKPIQQSIKER------------IMLSETDS 284
            ||.:|....:.|| |.|:..|.:||::|.  .|.|..:::.::||            .:|.:...
Zfish   801 DRPEFSHISVLLRKQNREHRSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILP 865

  Fly   285 DRIVVNARRTENFMAIQIHPDVSILYADVVNYTHLTTTLTVEKLVKVLHDLYGRFDMAASTFKVQ 349
            ..:....:|.|...| :....|:|.::|:|.:|.|:...|..::|.:|:|||..||.....|.|.
Zfish   866 HSVAEQLKRGETVQA-EAFDSVTIYFSDIVGFTSLSAESTPLQVVTLLNDLYTCFDAIIDNFDVY 929

  Fly   350 RIKFLGDCYYCVAGL----GEADPDHARMAVSLGISMIANIQEVRAHRALD--IDMRIGVHSGTL 408
            :::.:||.|..|:||    |:.   |.|....:.::::..::..:.....|  :.:|||:|||.:
Zfish   930 KVETIGDAYMVVSGLPVRNGKL---HGREIARMSLALLEAVKTFKIRHRPDEQLKLRIGIHSGPV 991

  Fly   409 LAGVIGQAKLQYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSLNVAEYTVFPGTEVAQSDPILQ 473
            .|||:|....:|.::|..|:.::|:|:.|:|..:|||..|.:.|.  |:..|. .|:.....:..
Zfish   992 CAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVSSATRAVLQ--EFNCFQ-LELRGDVEMKG 1053

  Fly   474 KQPMTTYLL 482
            |..|.||.|
Zfish  1054 KGKMRTYWL 1062

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AC_N	<36..276	CDD:292831	13/43 (30%)
		CYCc	249..459	CDD:214485	62/229 (27%)
		Nucleotidyl_cyc_III	298..484	CDD:299850	57/191 (30%)
		CYCc	825..1047	CDD:214485
		Nucleotidyl_cyc_III	853..1072	CDD:299850
npr1b	XP_009290669.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900