Protein Alignment ACXB and gucy1a1

DIOPT Version :9

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_001296458.1
• Gene: gucy1a1 / 550420
• ZFINID: ZDB-GENE-050417-230
• Length: 679
• Species: Danio rerio
• Alignment Length: 568
• Identity: 121/568 - (21%)
• Similarity: 211/568 - (37%)
• Gaps: 181/568 - (31%)

  Fly    36 LEEEYKKYQIR-------LMISY-LTVFFPLF-----IFVVVGCELCPWIFS------------- 74
            |.:..|.|.::       |.||. |.||...:     |..|||..|..::.|
Zfish   116 LSDVMKNYSLKTGIPMDALKISLGLEVFRDCYEEDGHILRVVGGALHDFLNSFNVLLKQSTPPTP 180

  Fly    75 EQKKLIYYESLTAIVVLVAVPGILSINFFESFVLRHRWIMVFSSILSA----------------- 122
            |.::.|:..|   |:.|...||:|::.||.......   :.||.|:.|
Zfish   181 EIQRYIHQAS---ILCLDKDPGLLTVYFFNPLPSTE---LFFSGIIQAAACLLYCTRVEVRMDVG 239

  Fly   123 ----------------YIVVLVDIFQILVFHFKYHW----PLNTLYDVFVLCMI----------- 156
                            |.||:.|...:.....:.|.    ||:.||..|...::
Zfish   240 GKDSGALQADHQPHLLYSVVVRDGRSLTPSPMRTHTSGDIPLSLLYSTFPFHILLDQEMGLLQIG 304

  Fly   157 ---------------------YMFLPIPSIRGAAL-LATSVSLMYI------------------- 180
                                 :..:..|.||.:.. :.|.::..::
Zfish   305 DGLRRRLGRCRDGQRRPAFNEHFAIVSPEIRASFQDILTMLNTQFLLRVKQHGASSADSPGKHMD 369

  Fly   181 --GLFIYFLKSDDEDISEVVHDLDTICVDIFHYL---GFNLMGI-FFRIMNDTMV---------- 229
              |..|:.     .::|.::. |.:.|||....|   |..|..| ....:.|.::
Zfish   370 LKGQMIFM-----SEMSALLF-LGSPCVDKLEELTGRGLYLSDIPIHNALRDVVLVGEQTKAQDG 428

  Fly   230 --------RSSFLDRHQFLKEEMWLRQARQQESMLLDSILPPQIAKPIQQSIKERIMLSETDSDR 286
                    :::....||.|:||      :::...||.:|.|..:|:.:.|.:.
Zfish   429 LKKRLGKAKAALEQAHQALEEE------KRRTVELLFTIFPGNVAQRLWQGLP------------ 475

  Fly   287 IVVNARRTENFMAIQIHPDVSILYADVVNYTHLTTTLTVEKLVKVLHDLYGRFDMAASTFKVQRI 351
              |.|::.::         |::|::|:|.:|.:.:..|..::|.:|.:||.|||.......|.::
Zfish   476 --VQAKKFDH---------VTVLFSDIVGFTAICSRCTPMQVVNMLSELYTRFDHHCGELDVYKV 529

  Fly   352 KFLGDCYYCVAGLGEADPDHARMAVSLGISMIANIQEVRAHRALDIDMRIGVHSGTLLAGVIGQA 416
            :.:||.|....||.:..|.||.....:.:.|:....||.......|.||||:|||::||||:|..
Zfish   530 ETIGDAYCVAGGLHKESPTHAVQIALMALKMMELSDEVTTPMGEVIRMRIGIHSGSVLAGVVGVK 594

  Fly   417 KLQYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSL-NVAEYTVFPGT 463
            ..:|.::|.:|.:||:.|:...|..::||..|...| :..|:|:.|.|
Zfish   595 MPRYCLFGNNVTLANKFESCSLPRKINVSPTTYRLLKDCPEFTLIPRT 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AC_N	<36..276	CDD:292831	66/378 (17%)
		CYCc	249..459	CDD:214485	58/210 (28%)
		Nucleotidyl_cyc_III	298..484	CDD:299850	53/167 (32%)
		CYCc	825..1047	CDD:214485
		Nucleotidyl_cyc_III	853..1072	CDD:299850
gucy1a1	NP_001296458.1	HNOBA	279..470	CDD:285003	31/202 (15%)
		CYCc	449..635	CDD:214485	59/214 (28%)
		Guanylate_cyc	476..647	CDD:278633	55/176 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900