Protein Alignment ACXB and Gucy1a1

DIOPT Version :10

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_058786.2
• Gene: Gucy1a1 / 497757
• RGDID: 68436
• Length: 690
• Species: Rattus norvegicus
• Alignment Length: 337
• Identity: 80/337 - (23%)
• Similarity: 144/337 - (42%)
• Gaps: 68/337 - (20%)

  Fly   152 VLCMIYMFLPIPSIRGAALLATSVSLMYI-GLFIYFLKSDDEDISEVVHDLDTICVDIFHYLGFN 215
            ::.|:.|...|...|...|:..|..:|.: |..||.::      |..:..|.:.|||...  .|.
  Rat   337 IMTMLNMQFVIRVRRWDNLVKKSSRVMDLKGQMIYIVE------SSAILFLGSPCVDRLE--DFT 393

  Fly   216 LMGIFFRIMNDTMVRSSFLD---------------------------RHQFLKEEMWLRQARQQE 253
            ..|::   ::|..:.::..|                           .||.|:||      :::.
  Rat   394 GRGLY---LSDIPIHNALRDVVLIGEQARAQDGLKKRLGKLKATLEHAHQALEEE------KKKT 449

  Fly   254 SMLLDSILPPQIAKPIQQSIKERIMLSETDSDRIVVNARRTENFMAIQIHPDVSILYADVVNYTH 318
            ..||.||.|.::|:.:.|.              .:|.|::..         :|::|::|:|.:|.
  Rat   450 VDLLCSIFPSEVAQQLWQG--------------QIVQAKKFN---------EVTMLFSDIVGFTA 491

  Fly   319 LTTTLTVEKLVKVLHDLYGRFDMAASTFKVQRIKFLGDCYYCVAGLGEADPDHARMAVSLGISMI 383
            :.:..:..:::.:|:.||.|||.......|.:::.:||.|....||......||.....:.:.|:
  Rat   492 ICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHRESDTHAVQIALMALKMM 556

  Fly   384 ANIQEVRAHRALDIDMRIGVHSGTLLAGVIGQAKLQYDIWGPDVDIANRLEATGKPGYVHVSGRT 448
            ....||.:.....|.||||:|||::.|||:|....:|.::|.:|.:||:.|:...|..::||..|
  Rat   557 ELSNEVMSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPTT 621

  Fly   449 LSSLNVAEYTVF 460
            ...|......||
  Rat   622 YRLLKDCPGFVF 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AcyC	85..452	CDD:441717	77/327 (24%)
		Nucleotidyl_cyc_III	298..484	CDD:448371	47/163 (29%)
		Nucleotidyl_cyc_III	853..1072	CDD:448371
Gucy1a1	NP_058786.2	HNOBA	276..465	CDD:462234	30/144 (21%)
		Guanylate_cyc	471..642	CDD:425528	49/172 (28%)