Protein Alignment ACXB and Ac3

DIOPT Version :10

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: XP_061511365.1
• Gene: Ac3 / 4578014
• VectorBaseID: AGAMI1_012876
• Length: 1207
• Species: Anopheles gambiae
• Alignment Length: 1110
• Identity: 287/1110 - (25%)
• Similarity: 502/1110 - (45%)
• Gaps: 188/1110 - (16%)

  Fly    36 LEEEYKKYQIR-LMISYLTVFFPLFIFVVVGCELCPWIFSEQKKLIYYESLTAIVVLVAVPGILS 99
            |::.|:.|.:: ..:::........:|.|       |..:..:.    :|:.:|||...   .|:
Mosquito    26 LDKLYQSYALKQKRVAFACYLIASILFDV-------WAIAVPQG----QSVESIVVTSV---FLT 76

  Fly   100 INFFESFVLRHRWIMVFSSIL------SAYIVVLVDIFQILVFHFKYHWPLNTL-YDVFVLCMIY 157
            ||...:.|||......|..::      .|:::.:..:| :.:|......|.::| :.|.:..::|
Mosquito    77 INIVLAIVLRFCGRGRFRGVIWEIAPHLAWLLAIKQLF-LQLFLKGSVTPRDSLGWAVLLNFLVY 140

  Fly   158 MFLPIPSIRGAALLATSVSLMYIGLFIYFLKSDDEDISEVVHDLDTICVDIFHYLGFNLMGIFFR 222
            :.||:.......||.......|:...|...|.::....:.|       .:|...:...|:|:...
Mosquito   141 VTLPVLLKYTGILLGLGSFATYVNAIIGLAKKENYFWEQQV-------ANILLLIAATLIGLLCY 198

  Fly   223 IMNDTMVRSSFLDRHQFLKEEMWLRQARQQESMLLDSILPPQIAKPIQQSIKERIMLSETDSDRI 287
            .:.:...|.:||:..|.|:.:|.:.:...::..||.|:||..:|      :|.|..|..|:|
Mosquito   199 FLAEAKQRRAFLEAKQGLEVKMLIEEQSAEQERLLLSVLPEHVA------VKMRQDLGSTNS--- 254

  Fly   288 VVNARRTENFMAIQI--HPDVSILYADVVNYTHLTTTLTVEKLVKVLHDLYGRFDMAASTFKVQR 350
                   |.|..|.:  |.:|||||||:|.:|.:::|.:.:.|||:|::|:.|||..|..::..|
Mosquito   255 -------EQFKKIYMSRHENVSILYADIVGFTAISSTYSAQDLVKILNELFARFDRLAEKYQQLR 312

  Fly   351 IKFLGDCYYCVAGLGEADPDHARMAVSLGISMIANIQEVRAHRALDIDMRIGVHSGTLLAGVIGQ 415
            ||.|||||||::|.....||||.:.|.:|:||:..|:.|:......:|||:|:|:|.:|||::||
Mosquito   313 IKILGDCYYCISGAPVERPDHAVLCVHMGLSMVKAIKYVQQKTNSPVDMRVGIHTGAVLAGILGQ 377

  Fly   416 AKLQYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSLNVAEYTVFPGTEVAQSDPILQKQPMTTY 480
            .:.|:|::..||::||::|::||.|.||:|.:||..|| .|:.|.|... .:.:..|:...:.||
Mosquito   378 RQWQFDVYSKDVELANKMESSGKAGRVHLSEKTLGFLN-GEFEVEPAFG-EKREEALRIAGLKTY 440

  Fly   481 LLTA-----APSRNSVRSVDAVHSYAEIDINALGASRKSPILRPTLMSDELRE-EFKKMPVGGFN 539
            .:|.     .||.:...|.|.                |..::.|...|:.||| :....|..|.|
Mosquito   441 FITKVLKPFCPSEHKNGSADP----------------KDVVIEPDGPSEILREDDDDTKPANGAN 489

  Fly   540 IRSPCCRDNSNDE-----------------------------KVNHGLGMFCVAFKDSSLEWSY- 574
            .........::|:                             :::....:| :.|.|.:.|.:|
Mosquito   490 AGDEPSTPGTDDKTDPLEDDTQASEDYKMRLRKELVSRDGHSEISKDTTIF-LTFNDKTHETAYN 553

  Fly   575 -LHKP-DFILKYSVLLAWGIGCCLIYIQIVNDKFTICVECIVIDMVVFTFLTSLLFISWFKKVCW 637
             ..:| ..:...:.||...:  .::|..:|..:..:..| |||..:|..|:  ::|||..:.:.
Mosquito   554 EYREPHSAVPLLAALLVQFV--AILYALLVLPRTAVHFE-IVIPPLVIIFV--MVFISVAESLT- 612

  Fly   638 WRCVENDSRKYGRVSCKLFKIWERIQHSFVLRVTIYMSIVASYYLL----ISTILLNCDKNQYEL 698
                       |.:...:....:|...|..||.:..:.||   .||    :|.:|....:....|
Mosquito   613 -----------GILPAFITLNSKRYNDSTSLRKSTAIIIV---LLLGVSNVSDMLAASHRTPLSL 663

  Fly   699 DVINSKLYHYDIVTDN-CFNPWVFTDMISLIVGVSYTFARIPFALKMLITCCATV--AYLVIVFF 760
            ::.|......::...: |..|..|::...||:..:....::....|:|:....|.  .|:.|...
Mosquito   664 NITNVSFASTEMEPASVCLFPSYFSNYTVLILIATSIITQLSHLSKILLMIIITAIHCYVNIFHL 728

  Fly   761 QYSFIFEHSATTTPFMKAELAHCLRVCMMLLTMYAKERQSEFNTKINFKINQDLQGKQKAADITN 825
            ..:|..|.......|........|.|.:.:...:......:.:..|.....:.:..|:||:|:..
Mosquito   729 DEAFRNEDFGIMNVFPLRYTLSALLVAVTIALSFLARHIDKVDRVIFMWKTEVIDQKEKASDMRR 793

  Fly   826 KSIIILLTNILPSHVVEVYLDS--VANHELYYENYKMVSVMFAMLINF----------QMDLPSL 878
            :: ..|:.|:||.||.|.::.:  .::.:||.::|..|.|:||.:.||          ...|..|
Mosquito   794 RN-EALVYNVLPMHVAEHFMGNRKRSHDDLYSQSYAEVGVLFASMPNFSDFYSEETVNNQGLECL 857

  Fly   879 RVLNDIITEFDRLLNAYKEYYVVEKIKVVGCTYMAACGLDFTLAKSKFGSRTHASYSSELEQVLY 943
            |.||::|::||.||. ..::..:.|||.:|.|||||.||:
Mosquito   858 RFLNEVISDFDALLE-LPQFQDIIKIKTIGSTYMAASGLN------------------------- 896

  Fly   944 RKESKGTENDHDEVAF------IMTTFALDLMRVLSVCNKAYAGRPFDRALSTGEICIGISTGEI 1002
              .|:..:.| |.|:.      ::..|||:|.:.|...|        :::.:...:.:|::.|.|
Mosquito   897 --PSRIVKPD-DPVSVRWAHLALLVEFALELKKALQGIN--------EQSFNHFVLKMGVNHGPI 950

  Fly  1003 MAGVVGASQPHYDIWGNPVNMASRMESTGLPGHIHVTQETANILEQFDIMCMYRGMTFVKGRGEI 1067
            .|||:||.:||||||||.||:||||||||..|.|.||:||..||:.|......||:..|||:|::
Mosquito   951 TAGVIGARKPHYDIWGNTVNVASRMESTGKAGAIQVTEETCQILQTFGYTFEQRGLVAVKGKGQL 1015

  Fly  1068 PTYFV 1072
            .||::
Mosquito  1016 MTYYL 1020

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AcyC	85..452	CDD:441717	115/375 (31%)
		Nucleotidyl_cyc_III	298..484	CDD:448371	76/187 (41%)
		Nucleotidyl_cyc_III	853..1072	CDD:448371	83/234 (35%)
Ac3	XP_061511365.1	None