Protein Alignment ACXB and CG43373

DIOPT Version :10

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Alignment Length: 1080
• Identity: 299/1080 - (27%)
• Similarity: 484/1080 - (44%)
• Gaps: 252/1080 - (23%)

  Fly   113 IMVFSSILSAYIVVLV------DIFQILVFH------------FKYHWPLNTLYD-----VFVLC 154
            :|:...|:.|:::.::      :||.:||.:            ..|....:..::     :.::.
  Fly   530 VMLICGIVYAFLLCILSKPAMNEIFLVLVSYVILGTFLAIEVAVSYAMQPSKSFNGSACCIVLIY 594

  Fly   155 MIYMFLPIPSIRGAALLATSVSLMYIGLFIYFLKSDDEDISEVVHDLDTICVDIFHYLGFNLMGI 219
            |.|..||: .:|.|.:....:|::::...:......||.: |::|..:.:|..:...|. ||.|:
  Fly   595 MTYTMLPL-RLREALIGGILLSVVHLYTCLRLNAMQDEAV-EMIHWEELLCTLVALLLA-NLTGV 656

  Fly   220 FFRIMNDTMVRSSFLDRHQFLKEEMWLRQARQQESMLLDSILPPQIAKPIQQSIKERIMLSETDS 284
            :.....:...|.:|::..|.::..:..::..||:..||.|:||..:|..::
  Fly   657 YTHWPKEKAQRKAFIETRQCIEARLRTQRENQQQERLLLSVLPRHVAMEMK-------------- 707

  Fly   285 DRIVVNARRTE-NFMAIQIHPDVSILYADVVNYTHLTTTLTVEKLVKVLHDLYGRFDMAASTFKV 348
            |.|....|.|: :.:.||.|.:||||:||:..:|.|:...|.|:||::|::|:.|||..|:....
  Fly   708 DDIAGQPRDTQFHKIYIQRHENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHC 772

  Fly   349 QRIKFLGDCYYCVAGLGEADPDHARMAVSLGISMIANIQEVRAHRALDIDMRIGVHSGTLLAGVI 413
            .|||.||||||||:||.|..||||..||.:|:.||..|..||...|::::||:|:|:|.:..||:
  Fly   773 LRIKLLGDCYYCVSGLPEPRPDHAHCAVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCGVL 837

  Fly   414 GQAKLQYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSLNVAEYTVFPGTEVAQSDPILQKQPMT 478
            |..|.|:|:|..||.:||.:|:.|.||.||::..||..|: .:|.|..| :..:.:..|:...:.
  Fly   838 GLVKWQFDVWSNDVTLANHMESGGIPGRVHITKETLKCLD-GDYEVEVG-KGNERNSYLKDHQIE 900

  Fly   479 TYLLTAA-------PSRNSVRSVDAV--------HSYAEIDINALG-----ASRKSPILRPTLMS 523
            |||:...       .|||.::....:        |..|:...:..|     .|.|.|       .
  Fly   901 TYLIVPGDIYRPHKKSRNRLQVNGNISKELRMMGHGTAQKHTSKFGFGDSSESAKDP-------E 958

  Fly   524 DELREEFKKMPVGGFNIRSPCCRDNSNDEKVNHGLGMFC----VAFKDSSLEWSYLHKPDFILKY 584
            ||:.|...:    ..:.||           ::|.....|    :.|||:.||..|..:||.:|
  Fly   959 DEVNEYLMR----AIDARS-----------IDHLRAEHCQSLLLCFKDNVLERKYASEPDRML-- 1006

  Fly   585 SVLLAWGIGCCLIYIQIVNDKFTICVECIVIDMVVFTFLTS---------LLFISWFKKVCWWRC 640
                     |...|..::....|..:..:|....:.|...|         |:|:....|:.:.
  Fly  1007 ---------CVYFYCSLLVLLGTSIMRLVVFQSSLLTLALSTGALLLLGFLVFLVACHKINFQ-- 1060

  Fly   641 VENDSRKYG-RVSCKLFKIWERIQHSFVLRVTIYMSIVASYYLLISTILLN-----------CDK 693
            :.:|.:::. |:...     .||...|..         ||..|::.|.||.           ..:
  Fly  1061 LPSDIKRFSLRIHSN-----RRISQLFAF---------ASVALIVLTTLLAMFQESGRQMELLQR 1111

  Fly   694 NQYELDV----------INSKLYHYDIVTDNC-----FNPWVFTDMISLIVGVSYTFARIPFALK 743
            .::.|||          :|:|:  ||....:|     :|.::...::|::...:|...||  .||
  Fly  1112 RRFWLDVNGSISLNDTELNTKM--YDAEEPDCDFYLAYNTFLLLTLLSMMSCATYQVLRI--LLK 1172

  Fly   744 MLITCCATVAYLVIVFFQYSFIFEHSATTTPFMKAELAH---CLRVCM-------MLLTMYAKER 798
            :|:...|:.:|:......||...|        |..|||:   .||..:       .:|.:.....
  Fly  1173 LLLLLLASGSYMACSSNLYSRSRE--------MSQELANEEALLRYIIDSIFLFAFMLALIFHSH 1229

  Fly   799 QSEFNTKINFKINQDLQGKQKAADIT-----NKSIIILLTNILPSHVVEVYLDSVANH--ELYYE 856
            |:|...:::|  ...||..::..|:.     |:.   ||.||||.||.|.:| |...|  :||:|
  Fly  1230 QTEATYRLDF--IWKLQATEEKEDMEHLQAYNRK---LLENILPVHVAEHFL-SREKHLDDLYHE 1288

  Fly   857 NYKMVSVMFAMLINFQ---MDLPS-------LRVLNDIITEFDRLLNAYKEYYVVEKIKVVGCTY 911
            ....|.::||.:.||.   ::|..       ||:||:||.:||.||:. :.:..:||||..|.||
  Fly  1289 QCDSVCILFASIPNFSEFYVELEGNNEGVECLRLLNEIIADFDELLSE-ERFRCIEKIKSTGATY 1352

  Fly   912 MAACGLDFTLAKSKFGSRTHASYSSELEQVLYRKESKGTENDHDEVAFIMTTFALDLMRVLSVCN 976
            |||.||                                |.|..|.|.|...|...|
  Fly  1353 MAASGL--------------------------------TANTCDRVNFSHVTAMAD--------- 1376

  Fly   977 KAYAGRPFDR-------ALSTGEICIGISTGEIMAGVVGASQPHYDIWGNPVNMASRMESTGLPG 1034
              ||.:.||:       :.:...:.|||:.|.::|||:||.:|.||||||.||:||||:||||..
  Fly  1377 --YALQLFDKIEEVNMHSFNNFRMRIGINIGPVVAGVIGACKPQYDIWGNAVNVASRMDSTGLVD 1439

  Fly  1035 HIHVTQETANILE--QFDIMCMYRGMTFVKGRGEIPTYFV 1072
            ||.||||...|||  .|::.|  ||...|||:|.:.|||:
  Fly  1440 HIQVTQEMQQILEGRGFELTC--RGSVDVKGKGSMITYFL 1477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AcyC	85..452	CDD:441717	111/362 (31%)
		Nucleotidyl_cyc_III	298..484	CDD:448371	80/185 (43%)
		Nucleotidyl_cyc_III	853..1072	CDD:448371	87/237 (37%)
CG43373	NP_001097622.2	AC_N	<523..720	CDD:318454	39/206 (19%)
		Guanylate_cyc	722..904	CDD:425528	79/183 (43%)
		Adcy_cons_dom	<949..1005	CDD:461877	18/77 (23%)
		Guanylate_cyc	1285..1479	CDD:425528	88/239 (37%)