Protein Alignment ACXB and ACXD

DIOPT Version :10

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_620469.2
• Gene: ACXD / 38284
• FlyBaseID: FBgn0040507
• Length: 1162
• Species: Drosophila melanogaster
• Alignment Length: 1156
• Identity: 448/1156 - (38%)
• Similarity: 654/1156 - (56%)
• Gaps: 125/1156 - (10%)

  Fly    18 DERLWERGYLKAKCKELCLEEEYKKYQIRLMISYLTVFFPLFIFVVVGCELCPWIF---SEQKKL 79
            :|:.||..||..||:.|.||:.|..|..||.:.||:    ||||:.|...:...:.   :.:.|.
  Fly    31 NEKNWEWSYLVRKCRNLELEDSYDLYMRRLRVGYLS----LFIFIHVAVTVIHTLLLLTTPEIKY 91

  Fly    80 IYYESLTAIVVLVAVPGILSINFFESFVLRHRWIMVFSSILSAYIVVLVDIFQILVFHFKYHWP- 143
            :|.:.:..:...:.:..:|.:||....|.:|.|::..:|.|:..::||:|| .:.|:|...|..
  Fly    92 VYVDMVAYMCSGLVIWVVLGVNFRSELVSKHGWVVYATSWLAVCVMVLMDI-GLNVYHATSHNDI 155

  Fly   144 LNTLYDVFVLCMIYMFLPIPSIRGAALLATSVSLMYIGLFIYFLKS-DDEDISEVVHD-LDTICV 206
            ||.:||.:.|..||||:|:|.:....:|.::|:..||..:.:.:.: ||..:..:::: :...||
  Fly   156 LNPIYDAYTLYAIYMFMPVPYLLQPFVLGSAVTFCYIINYSFVITAKDDNQMHSILNEAIYLSCV 220

  Fly   207 DIFHYLGFNLMGIFFRIMNDTMVRSSFLDRHQFLKEEMWLRQARQQESMLLDSILPPQIAKPIQQ 271
                    ||:|||||:|.|..:|::||||.|:::|.:.||.||.||..||.||||.|||..:|:
  Fly   221 --------NLLGIFFRLMRDIALRTTFLDRRQYVEENLLLRYARDQERSLLLSILPAQIADRLQE 277

  Fly   272 SIKERIMLS-ETDSDRIVVNARRT-------------ENFMAIQIHPDVSILYADVVNYTHLTTT 322
            .:|.||..| :....:..|:.||:             ...:.|:.|.||::||||||||||||||
  Fly   278 DVKNRIERSKQQHQQQSQVDLRRSADSQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYTHLTTT 342

  Fly   323 LTVEKLVKVLHDLYGRFDMAASTFKVQRIKFLGDCYYCVAGLGEADPDHARMAVSLGISMIANIQ 387
            |.|:|||:.||||:.|||:|:..:.|.|||||||||||||||...:.|||:..|.||:.||.:|:
  Fly   343 LDVKKLVEALHDLFVRFDIASEEYNVLRIKFLGDCYYCVAGLANPNADHAKCCVDLGLRMIKDIR 407

  Fly   388 EVRAHRALDIDMRIGVHSGTLLAGVIGQAKLQYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSL 452
            :||..|.|:||||||||||.:|:||||.||.|:|||..||||||||||||..|.||||.:|||.|
  Fly   408 DVREKRHLNIDMRIGVHSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGRVHVSQKTLSLL 472

  Fly   453 NVAEYTVFPGTEVAQSDPILQKQPMTTYLLTA--APSRNSVRSVDAVHSYAEIDINALGASRKSP 515
            : .||....|||.|:.||:|||..:.|:|:.:  ||..:..|.:      .|..:..|..:.|:.
  Fly   473 D-GEYFFEDGTEKAREDPVLQKHGIRTFLIKSLRAPMHDPRRRM------RERQVKKLSEASKAN 530

  Fly   516 ILRPTLMSD----------ELREEFKKMPVGG------FNIRSPCCRDNSNDEKVNHGLGMFCVA 564
            .:..:.:..          |:..|..|||:|.      |...:...:|...:|.....:...|:.
  Fly   531 FMHNSTLHQYNQVRNQAKLEMCRELDKMPIGRIQLTKVFRRSTRLTQDEIEEETFRRNISSCCLF 595

  Fly   565 FKDSSLEWSYLHKPDFILKYSVLLAWGIGCCLIYIQIVNDKFTICVECIVIDMVVFTFLTSLLFI 629
            |:..:.|:.|:.:||.:||||:.|||.|...|:.||:::....  .....||......||.||.:
  Fly   596 FRIRNWEFQYIKEPDVMLKYSIALAWVIYMGLLTIQLLSKDAR--YHYWYIDGTTIILLTMLLIV 658

  Fly   630 SWFKKVCWWRCVEND---SRKYGRVSCKLFKIWERIQHSFVLRVTIYMSIVASYYLLISTILLNC 691
            ||:||:  |....:|   |...||:|..||::.:.:|.:.|:||.:|..|:.||..:....::.|
  Fly   659 SWYKKL--WIMYMSDADVSSPNGRLSGFLFRMSDEMQRNVVIRVVMYFLIIFSYCAVAIMQVVGC 721

  Fly   692 --DKNQYELDVINSKLYHYDIVTDNCFNPWVFTDMISLIVGVSYTFARIPFALKMLITCCATVAY 754
              |::..:||..      || ....||:||:.|:.::|::|:|:.|.||||.:|...:....:.|
  Fly   722 SSDEDYADLDPT------YD-ERVQCFHPWILTNCMTLVIGMSFLFTRIPFIIKSCFSALIMIGY 779

  Fly   755 LVIVFFQYSFIFEHSATTTPFMKAELAHCLRVCMMLLT---MYAKERQSEFNTKINFKINQDLQG 816
            .|:|..:::||:.:|.:|.....|:.:|.|   :|::|   .:..|||:||..|:::...:.|..
  Fly   780 AVLVVSEFNFIYANSPSTNVNFNAKYSHIL---LMIITFGIFHLMERQTEFIAKVDYNWKRQLIK 841

  Fly   817 KQKAADITNKSIIILLTNILPSHVVEVYLDSVANHELYYENYKMVSVMFAMLINFQMDLPSLRVL 881
            ||:.|.|||.:|.:|||||||:||.:.||.:...:|||||.|..|:||||.:.||..|...||||
  Fly   842 KQEDALITNDTIKVLLTNILPTHVADFYLSNQLQNELYYEEYDNVAVMFASIKNFDTDKIGLRVL 906

  Fly   882 NDIITEFDRLLNAYKEYYVVEKIKVVGCTYMAACGLDFT-------------------------- 920
            |:||.:||.:||.|.:...||||||...|||||||||.:
  Fly   907 NEIICDFDDVLNKYSQSLRVEKIKVANWTYMAACGLDVSRSEQVNAPQMKFRNVSLMPNGRRSRY 971

  Fly   921 ----------LAKSKFGSRTHASYSSELEQVLY---------RKESKGTENDHDEVAFIMTTFAL 966
                      :.:..:|:.::.:...:||:..|         |..|....:..:||..:|..|||
  Fly   972 DGARSSNADGVQRVPYGNGSNIALDLDLERGQYEGNVITSGPRISSTHNGSSSNEVVRVMAEFAL 1036

  Fly   967 DLMRVLSVCNKAYAGRPFDRALSTGEICIGISTGEIMAGVVGASQPHYDIWGNPVNMASRMESTG 1031
            ||||.:...|.......::.:...|.:.||||.|..||||||.|:||||||||||||||||:|||
  Fly  1037 DLMRTMRRFNTENMQTEYEGSTDYGMLRIGISHGRAMAGVVGISKPHYDIWGNPVNMASRMDSTG 1101

  Fly  1032 LPGHIHVTQETANILEQFDIMCMYRGMTFVKGRGEIPTYFVGIDDNLKFLP 1082
            :||.|.||:.||..|.:|:|.|.|||||||||||.||||.:|||...:|||
  Fly  1102 VPGQIQVTENTALKLREFNIQCNYRGMTFVKGRGNIPTYIIGIDSEYQFLP 1152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AcyC	85..452	CDD:441717	174/383 (45%)
		Nucleotidyl_cyc_III	298..484	CDD:448371	115/185 (62%)
		Nucleotidyl_cyc_III	853..1072	CDD:448371	115/263 (44%)
ACXD	NP_620469.2	AC_N	<42..284	CDD:318454	86/254 (34%)
		Nucleotidyl_cyc_III	321..503	CDD:448371	114/182 (63%)
		Nucleotidyl_cyc_III	878..1142	CDD:448371	115/263 (44%)