Protein Alignment ACXB and rut

DIOPT Version :10

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_511156.2
• Gene: rut / 32406
• FlyBaseID: FBgn0003301
• Length: 2248
• Species: Drosophila melanogaster
• Alignment Length: 1308
• Identity: 316/1308 - (24%)
• Similarity: 515/1308 - (39%)
• Gaps: 414/1308 - (31%)

  Fly    36 LEEEYKKYQIRLMISYLTVFFPLFIFVVVGCELCPWIFSEQKKLIYYESLTAIVVLVAVPGILSI 100
            ||..|::|.::|.           .|.|:|.                  :..:.||..|...||:
  Fly    23 LECLYQRYTLKLQ-----------RFSVLGV------------------VALVFVLCGVMAALSL 58

  Fly   101 NFFESFVLRHRWIMVFSSILSAYIVVLVDIFQILVFHFKYHWP--------------------LN 145
            .|..:....:    :|::|:.....|::.:.|..|.. .:|.|                    |.
  Fly    59 TFNNAATFHN----IFNAIVCGLFAVVLVLLQCSVIK-DHHLPTLCYGILLFTASICVVSMPTLG 118

  Fly   146 TLYD--------------VFVLCMIYMFLPIPSIRGAALLATSVSLMYIGLFIYFLKSDDEDISE 196
            :::.              |||:.:.|..:|: .|..|.....::..::|.|.:|.:.:|.....|
  Fly   119 SVFPVDTKEVMAEGVWQIVFVVFLAYAMMPL-QIWEAVAFGIALPSVHISLTVYKIFTDALRYLE 182

  Fly   197 VVHDLDTICVDIFHYLGFNLMGIFFRIMNDTMVRSSFLDRHQFLKEEMWLRQARQQESMLLDSIL 261
                .:.:..:|..::|.|:.|:...||.:...|.:|||....:...:.::...::...||.|:|
  Fly   183 ----YNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVL 243

  Fly   262 PPQIAKPIQQSIKERIMLSETDSD--RIVVNARRTENFMAIQIHPDVSILYADVVNYTHLTTTLT 324
            |..:|..::..|     ||.....  ||.           ||.|.:||||:||:|.:|.|::..:
  Fly   244 PQHVAMQMKNDI-----LSPVAGQFHRIY-----------IQKHENVSILFADIVGFTVLSSQCS 292

  Fly   325 VEKLVKVLHDLYGRFDMAASTFKVQRIKFLGDCYYCVAGLGEADPDHARMAVSLGISMIANIQEV 389
            .::||::|::|:||||..|......|||.||||||||:||.|...|||:.||.:|:.||..|..|
  Fly   293 AQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATV 357

  Fly   390 RAHRALDIDMRIGVHSGTLLAGVIGQAKLQYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSLNV 454
            .....:.::||:|:|:|.:|.||:|..|.|:|:|..||.:||.:|:.|:||.|||:..||.||:
  Fly   358 VEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLS- 421

  Fly   455 AEYTVFPGTEVAQSDPILQKQPMTTYLLTAAPSRN--------SVRSVDAVHSYAEIDINALGAS 511
            .||.|..|....:|. .|:...:.|:.:...|.|.        .|||             |:|:.
  Fly   422 GEYEVEAGHGDERSS-YLRDHGVDTFFIVPPPHRRKPLMLNTLGVRS-------------AIGSR 472

  Fly   512 RK------SPILRPTLMSDELRE--EFKKMPVGGFN-----------------------IRSPCC 545
            ||      |.::...|.:.:..|  .|..:..|.|.                       .|...|
  Fly   473 RKLSFRNVSNVVMQLLHTIKFSEPVPFSNIATGSFPSAASALGGGVSVGGGGGGGGGGVARGSTC 537

  Fly   546 RDNSNDEKVN--------------------HGLGM------------------FCVA-------- 564
            ..||.:.:|:                    ||:|.                  .||:
  Fly   538 EANSGNVQVSEKGSRKVIRLQKILHATPPPHGMGYGSVVGSGGGVDSGISGGGGCVSGGIAGGGG 602

  Fly   565 ----------------------------------------------------------------- 564
                                                                             
  Fly   603 VQVTVGTNPNSTASTISRIHRHNHKNNKSQSKVADKFKRPFRKRHSVAAHHQPTNRVNRFLSQAI 667

  Fly   565 -------------------FKDSSLEWSYLHKPDFILKYSVLLAWGIGCCLIY------IQIVND 604
                               |:.|.:|..| || ||.|.::.    .:||.|:.      :|:...
  Fly   668 NARSVDCDKSEHVDRLTLRFRQSDMEREY-HK-DFDLGFTT----AMGCSLLLLILGAALQVTAL 726

  Fly   605 KFTICVECIVIDMVVFTFLTSLLFISWFKKVCWWRCVENDSRKYGRVSCKLFKIWERIQHSFVLR 669
            ..|:.:  :::.:..|.:::::|.:....::.|                   .||: |..||.||
  Fly   727 PRTLIL--LLLFLFAFIWVSAILMLLLAVRLKW-------------------IIWD-ISESFSLR 769

  Fly   670 VTIYMSIVASYYLLISTILLNCDKNQYELDVINSKLYHYDIVTDN-----------------CFN 717
            :.|          .|.|::|     .|.:..:|.    :..|:|:                 |..
  Fly   770 MAI----------TIFTVIL-----IYSVGQVNV----FTCVSDHPCSGNGTTSFQNDSHRKCSL 815

  Fly   718 PWVFTDMISLIVGVSY----TFARIPFALKMLITCCATVAYLVIVFFQYSFIFE-HSATTTPFMK 777
            |    ..:||....::    .|.|:|...|.|:.......|.:.:...:..||| :.......:.
  Fly   816 P----QYVSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNASIP 876

  Fly   778 AELAHCLRVCMMLLTMYAKERQSEFNTKINFKINQDLQGKQKAADITNKSIIILLTNILPSHVVE 842
            ..|....|:.:.::.:....|..|...:::|........::|..|:..:|...:|.|:||:||..
  Fly   877 LHLISLARIAIFMIAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAA 941

  Fly   843 VYLDSV--ANHELYYENYKMVSVMFAMLINF-----QMD-----LPSLRVLNDIITEFDRLLNAY 895
            .:||:.  .|.|||:::|..|.|:||.:.||     :||     |..||:||:||.:||.||
  Fly   942 HFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELL--- 1003

  Fly   896 KE--YYVVEKIKVVGCTYMAACGL--DFTLAKSKFGS-RTHASYSSELEQVLYRKESKGTENDHD 955
            ||  :..::|||.||.||||..||  ::.:..:...| |.|  .::.:|.|...:.|....|.|.
  Fly  1004 KEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRH--MTALIEYVKAMRHSLQEINSHS 1066

  Fly   956 EVAFIMTTFALDLMRVLSVCNKAYAGRPFDRALSTGEICIGISTGEIMAGVVGASQPHYDIWGNP 1020
            ...|::.                                :||:.|.::|||:||.:|.||||||.
  Fly  1067 YNNFMLR--------------------------------VGINIGPVVAGVIGARKPQYDIWGNT 1099

  Fly  1021 VNMASRMESTGLPGHIHVTQETANIL--EQFDIMCMYRGMTFVKGRGEIPTYFVGIDDNLKFLPS 1083
            ||:||||:|||:||:..||||..:.|  ..|:..|  ||...|||:|::.|||: .|...|.|..
  Fly  1100 VNVASRMDSTGVPGYSQVTQEVVDSLVGSHFEFRC--RGTIKVKGKGDMVTYFL-CDSGNKSLNG 1161

  Fly  1084 NVKKNNMS 1091
            .| :|.||
  Fly  1162 EV-RNAMS 1168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AcyC	85..452	CDD:441717	118/402 (29%)
		Nucleotidyl_cyc_III	298..484	CDD:448371	80/185 (43%)
		Nucleotidyl_cyc_III	853..1072	CDD:448371	85/235 (36%)
rut	NP_511156.2	AC_N	<17..255	CDD:318454	50/270 (19%)
		Guanylate_cyc	266..428	CDD:425528	77/173 (45%)
		Adcy_cons_dom	624..698	CDD:461877	4/74 (5%)
		AcyC	742..1150	CDD:441717	132/489 (27%)
		Guanylate_cyc	954..1151	CDD:425528	85/235 (36%)