Protein Alignment ACXB and CG32305

DIOPT Version :9

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_728725.2
• Gene: CG32305 / 317967
• FlyBaseID: FBgn0052305
• Length: 1164
• Species: Drosophila melanogaster
• Alignment Length: 1177
• Identity: 385/1177 - (32%)
• Similarity: 619/1177 - (52%)
• Gaps: 122/1177 - (10%)

  Fly     2 YKKTAYAPRKCYLDYTDERLWERGYLKAKCKELCLEEEYKKY-QIRLMISYLTVFFPLFIFVVVG 65
            |::...|.|.  |....:..|.  :||.||:.|.||....:. ::.||.:.:.:.:.:.:.:|.
  Fly     8 YQEDVVAYRS--LSTVKDLEWR--HLKNKCQNLRLELACSRLRELALMSNVVQIIWHVELLMVA- 67

  Fly    66 CELCPWIFSEQKKLIYYESLTAIVVLVAVPGILSINFFESFV----LRHRWIMVFSSILS---AY 123
                        .:|...:|...::||.:....::..|..|:    :::...|:.::::|   |.
  Fly    68 ------------HVILLLALVKDIILVTMVPYFAVMLFSPFIMLLSMQNNVGMITNTLISWLMAL 120

  Fly   124 IVVLVDIFQILV--FHFKYHWPLNTLYDVFVLCMIYMFLPIPSIRGAA--LLATSVSLMYIGLFI 184
            .:..:|:...|:  .:....:|....||..||..:||.|||...:|::  :|...||::||| :.
  Fly   121 FLTSMDLVSDLLGTIYSGAAYPTVPCYDHVVLVSVYMTLPIAFYQGSSVYVLGMVVSIIYIG-YA 184

  Fly   185 YFLKSDDEDISEVVHDLDTICVDIFHYLGFNLMGIFFRIMNDTMVRSSFLDRHQFLKEEMWLRQA 249
            ::::..::.:|  .:.|.:..:.:|   ..||:..||.|:.|..:|.:.|.|:|.:.:.:..:..
  Fly   185 FYMQYLNDQVS--FYLLASYAIYLF---TLNLIFSFFTIIRDYGLRRAILSRYQLVYQNIVYQLV 244

  Fly   250 RQQESMLLDSILPPQIAKPIQQSIKERIMLSETDSDRIVVNARRTENFMAIQIHPDVSILYADVV 314
            .::|:.||:||||.::.:.:|:.|..||    .|.|:....::.....:.::.:|:||||.||:|
  Fly   245 MKKENGLLESILPRKMIRTLQEEICSRI----EDQDKNFTPSKAGLRKLFLEPYPNVSILVADMV 305

  Fly   315 NYTHLTTTLTVEKLVKVLHDLYGRFDMAASTFKVQRIKFLGDCYYCVAGLGEADPDHARMAVSLG 379
            |||||||||...:||::||||:..||:||:..:..|||||||.|.||||:....|.||...|...
  Fly   306 NYTHLTTTLEAPQLVEILHDLFVNFDLAANRNRAMRIKFLGDSYNCVAGIPNYFPAHASCCVDQA 370

  Fly   380 ISMIANIQEVRAHRALDIDMRIGVHSGTLLAGVIGQAKLQYDIWGPDVDIANRLEATGKPGYVHV 444
            :.||...|.|.:.|.|||::|||||||.:.||:||..|.|:|||..||||.||||::|.||.|||
  Fly   371 LEMIHITQGVSSRRELDINLRIGVHSGEVFAGIIGHTKWQFDIWSKDVDITNRLESSGLPGLVHV 435

  Fly   445 SGRTLSSLNVAEYTVF-PGTEVAQSDPILQKQPMTTYLLT----------------AAPSRNSVR 492
            |.||||.|:  |:.:| .|||.|::|||||:..:.|:|::                ::.|.||.|
  Fly   436 SQRTLSMLD--EHYIFREGTEAAKNDPILQQAGIRTFLVSNRLPDAVEPGELDDELSSASINSCR 498

  Fly   493 SVDAVHSYAEIDINALGASRKSPILRPTLMSDELREEFKKMPVGGFNIR----SPCCRDNSNDE- 552
             :.....|.||.|.|               ..|:.:|..:|.||...|.    |...:.:.|:|
  Fly   499 -LSYGGYYEEIQIKA---------------QREIMKEVDQMAVGHCFIEWRRSSSMKKQDFNEEY 547

  Fly   553 ----KVNHGLGMFCVAFKDSSLEWSYLHKPDFILKYSVLLAWGIGCCLIYIQIVNDKFTICVECI 613
                :::..||:    |:....||.:.:.||.::||::||....|..::.|.::.:   .....|
  Fly   548 LFSNQIHLVLGV----FRSWKREWEFHNLPDLMIKYTMLLVLCAGLAIMSINLIEE---ATYPDI 605

  Fly   614 VIDMVVFTFLTSLLFISWFKKV-CWWRCVENDSRKYGRVSCKLFKIWERIQHSFVLRVTIYMSIV 677
            ::.:.:...|..|..::.:||: ..|:.:...|:....:|..|.:|.|||:.|..:|:.:.|.::
  Fly   606 LVLLGILLILLILCILAGYKKLRLQWKKLTPMSQPSCFLSRWLLRISERIEDSLFVRIPLTMVVL 670

  Fly   678 ASYYLLISTILLNCDKNQYELDVINSKLYHYDIVTDNCFNPWVFTDMISLIVGVSYTFARIPFAL 742
            ...|::.|..:.:||..:.||.:|.:.||:.....: ||.||..|..:.:::.:.:.....|..:
  Fly   671 LLLYVMSSQAVFSCDVAKLELSIIEAHLYNEKSYAE-CFGPWTVTYCVVIVISLLFVVPGCPLVI 734

  Fly   743 KMLITCCATVAYLVIVFFQYSFIFEHSATTTPFMKAELAHCLRVCMMLLTMYAKERQSEFNTKIN 807
            |:|........:|..|...|.|.||.|.||...:|::.||...:..:.:.:..:||...:..|.|
  Fly   735 KILAGLLILGLHLGTVHLYYGFAFERSETTDLGLKSDYAHTWYLVALFIVLVLRERHVNYLRKFN 799

  Fly   808 FKINQDLQGKQKAADITNKSIIILLTNILPSHVVEVYLDSVANHELYYENYKMVSVMFAMLINFQ 872
            :.:....:...:..|...:||.|::.||||:||.:||.....:.:|||||:..|:||||.:.||.
  Fly   800 YFMRVCYEEAHQQTDEKLRSIKIIMANILPTHVAQVYKVRRPHDQLYYENFSKVAVMFASIENFN 864

  Fly   873 MDLPSLRVLNDIITEFDRLLNAYKEYYVVEKIKVVGCTYMAACGL------DFTL---------- 921
            .|...||:|::||..||.||..|:..|.:|||||:|.|||.||||      ||::
  Fly   865 ADTAGLRILHEIICCFDDLLVDYQTRYKIEKIKVMGWTYMVACGLETDHYTDFSIDIPVKQPEAD 929

  Fly   922 AKSKFGSRTHASY--SSELEQVLYRKESKGTENDHDEVAFIMTTFALDLMRVLSVCNKAYAGRPF 984
            ::.:.||.....:  |:|.:::.....|:......|....:||.|||||:|::......|....:
  Fly   930 SEIRRGSSVLTVHFGSTEDDEMSGDNVSQPYAQVQDVAVLVMTEFALDLLRIMHDIRYNYVFSEY 994

  Fly   985 DRALSTGEICIGISTGEIMAGVVGASQPHYDIWGNPVNMASRMESTGLPGHIHVTQETANILEQF 1049
            |..| ||.:.||||.|.:||||||.|:|||||||:.|||||||.||||..:|.||:.||.:|.||
  Fly   995 DTFL-TGSLKIGISHGSVMAGVVGLSKPHYDIWGHTVNMASRMSSTGLLDNIQVTRHTAKVLRQF 1058

  Fly  1050 DIMCMYRGMTFVKGRGEIPTYFVGIDDNLKFLPSNVKKNNM--SKRF-------SILSSLVPVHS 1105
            :|.|.|||.|.|||.|::|||.|.:|.:|.|...:....:|  ||.:       |...|.||  .
  Fly  1059 NIRCNYRGHTEVKGVGKVPTYLVVVDPDLTFQDHDQVSMSMKDSKSWVIDTLSLSFTPSFVP--P 1121

  Fly  1106 RSTTSSE 1112
            :|:||.|
  Fly  1122 KSSTSDE 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AC_N	<36..276	CDD:292831	55/251 (22%)
		CYCc	249..459	CDD:214485	101/209 (48%)
		Nucleotidyl_cyc_III	298..484	CDD:299850	100/202 (50%)
		CYCc	825..1047	CDD:214485	104/239 (44%)
		Nucleotidyl_cyc_III	853..1072	CDD:299850	109/236 (46%)
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	100/203 (49%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	87/154 (56%)
		CYCc	814..1056	CDD:214485	105/242 (43%)
		Nucleotidyl_cyc_III	845..1081	CDD:299850	109/236 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453914
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5262
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D181177at33208
OrthoFinder	1	1.000	-	-		FOG0007605
OrthoInspector	1	1.000	-	-		otm48748
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45627
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.800