Protein Alignment ACXB and Gucy1a2

DIOPT Version :10

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_001028494.1
• Gene: Gucy1a2 / 234889
• MGIID: 2660877
• Length: 730
• Species: Mus musculus
• Alignment Length: 318
• Identity: 81/318 - (25%)
• Similarity: 142/318 - (44%)
• Gaps: 64/318 - (20%)

  Fly   234 LDR-HQFLKEEMWLRQARQQESMLLDSILPPQIAKPIQQSIKERIMLSETDSDRIVVNARRTENF 297
            |:| ||.|:||      :::...||.||.|..:|:.:.|..:              |.||:.:
Mouse   474 LERTHQALEEE------KKKTVDLLYSIFPGDVAQQLWQGQQ--------------VQARKFD-- 516

  Fly   298 MAIQIHPDVSILYADVVNYTHLTTTLTVEKLVKVLHDLYGRFDMAASTFKVQRIKFLGDCYYCVA 362
                   ||::|::|:|.:|.:....|..:::.:|::||.|||.......:.:::.:||.|...:
Mouse   517 -------DVTMLFSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGLLDIYKVETIGDAYCVAS 574

  Fly   363 GLGEADPDHARMAVSLGISMIANIQEVRAHRALDIDMRIGVHSGTLLAGVIGQAKLQYDIWGPDV 427
            ||......||:....:.:.|:...:||.......|.||||:|||::||||:|....:|.::|.:|
Mouse   575 GLHRKSLCHAKPIALMALKMMELSEEVLTPDGKAIQMRIGIHSGSVLAGVVGVRMPRYCLFGNNV 639

  Fly   428 DIANRLEATGKPGYVHVSGRTLSSLNVAE-YTVFPGTEVAQSDPILQKQPMTTYLLTAAPSRNSV 491
            .:|::.|:...|..::||..|...|...: :|..|.:.....|...::.|...|.|
Mouse   640 TLASKFESGSHPRRINVSPTTYQLLKREDSFTFIPRSREELPDNFPKEIPGVCYFL--------- 695

  Fly   492 RSVDAVHSYAEIDINALGASRKSPILRPTLMSDELREEFKKMPVGGFNIRSPCCRDNS 549
                           .|....|.|  :|:|.|..:    ||:   .:||.:...|:.|
Mouse   696 ---------------ELRTDPKPP--KPSLSSSRI----KKV---SYNIGTMFLRETS 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AcyC	85..452	CDD:441717	62/218 (28%)
		Nucleotidyl_cyc_III	298..484	CDD:448371	52/186 (28%)
		Nucleotidyl_cyc_III	853..1072	CDD:448371
Gucy1a2	NP_001028494.1	HNOB	<157..268	CDD:462233
		HNOBA	314..501	CDD:462234	12/32 (38%)
		Guanylate_cyc	512..696	CDD:425528	54/216 (25%)