Protein Alignment ACXB and gcy-31

DIOPT Version :9

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_001024889.1
• Gene: gcy-31 / 191655
• WormBaseID: WBGene00001551
• Length: 702
• Species: Caenorhabditis elegans
• Alignment Length: 577
• Identity: 121/577 - (20%)
• Similarity: 215/577 - (37%)
• Gaps: 181/577 - (31%)

  Fly    54 VFFPLFIFVVVGCELCPWIFSEQKKLIYYESLTAIVVLVAVPGILSINFFESFVL-----RHRW- 112
            :||.:|.|::|        |:...::    ....|.:|..:.||:.....::|:|     |.||
 Worm   211 IFFDIFPFIIV--------FNRGMRI----RNIGIGLLRVMAGIVGKKINQTFLLMRPFIRFRWE 263

  Fly   113 -IMVFSSILSAYIVVLVDIFQILVFHFKYHWPLNTLYDVFVLCMIYMFLPIPSIRGAALLATSVS 176
             ||:.|:          :||:::...     |:....|
 Worm   264 EIMLHSN----------NIFELISSD-----PIQEDED--------------------------- 286

  Fly   177 LMYIGLFIYFLKSDDED-ISEVVH---------------------DLDTICVDIFHYLGFNLM-- 217
                |:.:|  |:.|.| ::|..|                     :.::||     ::|..:|
 Worm   287 ----GILVY--KTTDVDQMTEERHRMGDGEREKFLSLKGQMFYMEEWESIC-----FVGIPVMSH 340

  Fly   218 -------GIFFRIMNDTMVRSSFLD---------------------RHQFLKEEM-WLRQARQQE 253
                   |:|   :||..:..|..|                     :.:.::|.| .|::.|::.
 Worm   341 LPQMYKSGLF---INDFALHDSSRDLVLASTQQSAELKLLLHQEAQKSRNMRENMNRLKKERRRT 402

  Fly   254 SMLLDSILPPQIAKPIQQSIKERIMLSETDSDRIVVNARRTENFMAIQIHPDVSILYADVVNYTH 318
            ..||..:||..:|..::............||                     |:||:.|:|.:|.
 Worm   403 DKLLYQMLPKSVANQLRHGESAVACCERFDS---------------------VTILFTDIVEFTK 446

  Fly   319 LTTTLTVEKLVKVLHDLYGRFDMAASTFKVQRIKFLGDCYYCVAGLGEADPDHARMAVSLGISMI 383
            :.::||..::::.|..:|..||....|..|.:::.:||.|..|:|........|...:......:
 Worm   447 MCSSLTPLEVIEFLKVIYTNFDKIIDTHGVYKVETIGDAYMVVSGAPTKTEHDAEFILDCASQFL 511

  Fly   384 ANIQEV-----RAHRALDIDMRIGVHSGTLLAGVIGQAKLQYDIWGPDVDIANRLEATGKPGYVH 443
            ....::     :.|:   ||:|.|||||:::|||:|.:..:|.::|..|.:||::|....|..:.
 Worm   512 VEAGKMVNMNNKIHK---IDIRAGVHSGSVVAGVVGLSMPRYCLFGETVYVANKMEQNSSPMKIL 573

  Fly   444 VSGRTLSSLNVAEYTVFPGT---EVAQSDPILQKQPMTTYLLTA------APSRNSVRSVDAVHS 499
            ||..|.:.:..::    ||.   |..:...|...|.:.|:.:.:      .||..:..|......
 Worm   574 VSETTHNKIEESD----PGLYQFERREEIEIKDDQTIQTFFVVSRHGPHRVPSPRNCESRQDDSQ 634

  Fly   500 YAEIDINALGASRKSPILRPTLMSDELREEFKK------MPVGGFNIRSPCCRDNSN 550
            ..:.|.:.|...|||....||   .|..||.||      .||....|.  |...|||
 Worm   635 TEDDDDDELLLPRKSGRKSPT---SEAEEELKKKGQLSFTPVSDAGIE--CHSRNSN 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AC_N	<36..276	CDD:292831	48/281 (17%)
		CYCc	249..459	CDD:214485	51/214 (24%)
		Nucleotidyl_cyc_III	298..484	CDD:299850	49/193 (25%)
		CYCc	825..1047	CDD:214485
		Nucleotidyl_cyc_III	853..1072	CDD:299850
gcy-31	NP_001024889.1	HNOB	2..164	CDD:285002
		HNOBA	221..418	CDD:285003	44/264 (17%)
		CYCc	397..592	CDD:214485	53/222 (24%)
		Guanylate_cyc	429..613	CDD:278633	51/211 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910