Protein Alignment ACXB and gcy-4

DIOPT Version :9

• Sequence 1: NP_620474.2
• Gene: ACXB / 53427
• FlyBaseID: FBgn0040509
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_496218.2
• Gene: gcy-4 / 191642
• WormBaseID: WBGene00001531
• Length: 1136
• Species: Caenorhabditis elegans
• Alignment Length: 529
• Identity: 111/529 - (20%)
• Similarity: 204/529 - (38%)
• Gaps: 140/529 - (26%)

  Fly    37 EEEYKKYQI---------RLMISYLTVFFPLFIFVVVGCELC----PWIFSEQKKLIYYESLTAI 88
            |:.:||..:         .|.|..:.....::.|.:|..|:.    .|..|.:|     |....|
 Worm   706 EKPFKKNMLWAAPEVIRGSLSIEQMDSSADIYSFAIVASEILTKREAWDLSRRK-----EGYEEI 765

  Fly    89 VVLVAVPGILSINFFESFVLR---HRWIMVFSSILSAYIVVLVDIFQILVFHFKYHWPLNTLYDV 150
            ...|...|        .||||   |               :.:::.|.|:...|..|..|
 Worm   766 KYAVKKGG--------QFVLRPDLH---------------IDIEVNQTLLALVKDCWCEN----- 802

  Fly   151 FVLCMIYMFLPIPSIRGAALLATSVSLMYIGLFIYFLKSDDEDISEVVHDLDTICVDIFHYLGFN 215
                        |..|.:|                      |::.:|:.|:.....|       |
 Worm   803 ------------PEERPSA----------------------ENVCKVLFDMTPNTED-------N 826

  Fly   216 LMGIFFRIMNDTMVRSSFLDRHQFLKEEMWLRQARQQESMLLDSILPPQIAKPIQQSIKERIMLS 280
            ||...|.::.: ...|..::..:..||   |...:::..:||..:||.|:|        ||:...
 Worm   827 LMDHVFSMLEE-YTSSLEVEVGERTKE---LTLEKKKSDILLGRMLPKQVA--------ERLKAG 879

  Fly   281 ETDSDRIVVNARRTENFMAIQIHPD----VSILYADVVNYTHLTTTLTVEKLVKVLHDLYGRFDM 341
            :.                   :.|:    |::.::|:|.:|.|.:..:..::|.:|:|::..||.
 Worm   880 QA-------------------VEPESFDLVTVFFSDLVKFTDLASKCSPFQVVNLLNDVFSNFDS 925

  Fly   342 AASTFKVQRIKFLGDCYYCVAGLGEAD-PDHARMAVSLGISMIANIQEVR-AHRALD-IDMRIGV 403
            ......|.:::.:||.:.||:||...: .:|.|..|.:.:..:...:..| .|...: :::|:|:
 Worm   926 IIEKHDVYKVESIGDGFLCVSGLPNRNGMEHIRQIVGMSLCFMEFCRNFRIPHLPRERVELRVGI 990

  Fly   404 HSGTLLAGVIGQAKLQYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSLNVAEYTVFPGTEVAQS 468
            :||..:|||:|.:..:|.::|..|:.|:|:|:.|||..:|:| ....||.|..|.....|.....
 Worm   991 NSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGKPSMIHMS-EAAHSLLVNNYPYQFETNSRGE 1054

  Fly   469 DPILQKQPMTTYLLTA--APSRNSVRSVDAVH-------SYAEIDINALGASRKSPILRPTLMSD 524
            ..|..|..|.||.|..  :.|..|...:..|:       |:.:.::........||.:..  :||
 Worm  1055 VIIKGKGVMETYWLLGKMSLSNQSTPPITKVNHKPRKIASFTDSELTNYSFRSVSPYVEN--LSD 1117

  Fly   525 ELREEFKKM 533
            ...||.:::
 Worm  1118 NDDEEIRRV 1126

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXB	NP_620474.2	AC_N	<36..276	CDD:292831	46/254 (18%)
		CYCc	249..459	CDD:214485	54/216 (25%)
		Nucleotidyl_cyc_III	298..484	CDD:299850	53/192 (28%)
		CYCc	825..1047	CDD:214485
		Nucleotidyl_cyc_III	853..1072	CDD:299850
gcy-4	NP_496218.2	PBP1_NPR_GC_like	29..457	CDD:107347
		ANF_receptor	49..423	CDD:279440
		PKc_like	558..819	CDD:304357	30/179 (17%)
		HNOBA	<834..876	CDD:285003	11/53 (21%)
		CYCc	855..1047	CDD:214485	54/219 (25%)
		Guanylate_cyc	882..1070	CDD:278633	53/188 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900