Protein Alignment ACXE and si:dkey-37g12.1

DIOPT Version :9

• Sequence 1: NP_652601.3
• Gene: ACXE / 53426
• FlyBaseID: FBgn0040506
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: XP_021333677.1
• Gene: si:dkey-37g12.1 / 796669
• ZFINID: ZDB-GENE-090312-145
• Length: 882
• Species: Danio rerio
• Alignment Length: 1125
• Identity: 227/1125 - (20%)
• Similarity: 393/1125 - (34%)
• Gaps: 358/1125 - (31%)

  Fly    56 IFVTSVHCALLLATIERRSIIYFDVALSIGCALVLILVLSVNFCDEFIAKHTWYMYASSIFASLT 120
            |.::.|||:|   ....||..:..||                  ..:.|:|.          ::|
Zfish     9 IKLSDVHCSL---GFRARSTCWLPVA------------------QTYQAEHN----------NIT 42

  Fly   121 LV-FADLTESIYHTYAHSW--ILGTFYDTYIIYMIYMFLPIHFISGAVLLALLV----SGLYILY 178
            :. :.|:..|:......:|  :|........|.:|    ..|   |.|:.:||:    .||....
Zfish    43 VAKYQDIHSSLSQGSTSNWSRVLNEMAQVARIIVI----SAH---GKVVRSLLIEAHKKGLTNGD 100

  Fly   179 FVIFIAQGFAQFASALFS----VGGMSVDIV---HYLCLNLVGIF------YRVMNDTVVRSSFL 230
            ||.|..:.:.|  ..||.    ..|.|.|.:   .|..|..:.::      |:..::.|:..|.:
Zfish   101 FVFFCFEPYKQ--KVLFGSFDWEQGDSYDSMAKQAYQALFFLSLYKPSDKRYQAFSENVISRSKI 163

  Fly   231 D-RHQYIK------------EKIWLRNARLQEKQLLDSILPPQISLPLQKDIQGRIVMAKQGIHS 282
            | .:.|.:            :.:||....|.|  .|.....|...|.:.:.:..|.:...||
Zfish   164 DFGYTYAQTEKVSVLAAIAHDTVWLYAHALNE--TLAENGNPYDGLAVTRRMWNRTIKGIQG--- 223

  Fly   283 WTAMERTMAIQIHPDVSILYADV-----VNYTHLTTTLTVEMLVKVLHDLYGRFDLAAY---RYK 339
                          ||:|   |.     :||           ::|.:.....:..:.|.   .||
Zfish   224 --------------DVTI---DASGDRELNY-----------MMKQIRGSNNQCQVVANYFGTYK 260

  Fly   340 -VQRIKFLGDCYYCVAGLSDPDPDHANNCVILGLSMINHIMEVRDIHGLDINMRIGVHSGNLFAG 403
             |:.::.|..     .||:.| |..:.:|...|...||  :|.:.:      :.:|:.:|.:.||
Zfish   261 AVKGVQILWP-----GGLTSP-PKDSPDCGFRGELCIN--LERKFL------IALGIIAGLMAAG 311

  Fly   404 VIG------EAKLQFD----IWGLDVTIANVLE--STGVPGCVHISGATLNNLDVNRFDIEDGPE 456
            .:.      :.||..:    :|.::.....::|  |:.||...|.|.....:|:.....::|.|.
Zfish   312 TLAICVLYRKYKLPEEASKMLWTINANDVIMMEHHSSTVPEKSHRSKPLQASLESIICSMQDKPS 376

  Fly   457 EARDHPLLKKYRIRSYIIRQDLHMDDEDSDEFLGDLHSISLCNMGAQPRISDSANQSLRALFHEE 521
            ..|                         :..:.|.:.|:|..|:.     |...|..|.|    |
Zfish   377 AHR-------------------------TAVYKGTICSVSFVNLR-----STHLNSELLA----E 407

  Fly   522 LREEFRKMPVSAFSPKRLLGICRFNTGKEVPAHQNLNICLTFTDP------ILERAYLKQTDYMY 580
            |: :||.:        ....:|:| .|..:...|  ...||...|      ||:...:| .|:.:
Zfish   408 LK-QFRDL--------THYNLCKF-IGAALETSQ--PFILTEYCPKGSLQDILQNESIK-LDWTF 459

  Fly   581 KYSIILSASVGCSLVYI-------ELMDTQMICSSCFVLPASVATIQCILALIAWYKKYCWTRYG 638
            |:|::|....|...::.       .|..:..:..|.|||..                    |.:|
Zfish   460 KFSLMLDIVKGMDYLHHSPLQYHGHLSSSSCVVDSRFVLKV--------------------TDFG 504

  Fly   639 RNNVPH-------HYNGFSCFIFRIHDKILNSLPI----RICIYLFLMISSFFVMCLIVMSCQRE 692
            .|:|..       ..:.::..::|..:.:..|:|.    :..:|.|.:|:...|...........
Zfish   505 LNSVRRLDTEQSPGSDPWTALLWRAPELLRQSIPANGTQKGDVYSFAIIAQEVVYRRGPFYIPNS 569

  Fly   693 EFEMAYIEERLFHYEQEAHIC--FHPWV-----TTNMLSLMI-CLTFTFAHIP--IMVKTAVA-- 745
            .|....|.||:     .|..|  ..|::     ...:.||:: |...|.|..|  ..::||:.
Zfish   570 HFSPREIVERV-----RAGGCSPSRPYIDRAECVEELESLVVSCWRETPAERPDFSYIRTAIKKN 629

  Fly   746 --------ILETLAYLLLIFFQFDFVFHHSVTTNPYFKSEYAHALLICITFLIMFVKERQIEFTN 802
                    ||:.|...:                     .:||     |  .|...|.||..|
Zfish   630 SPHGVSENILDDLLSRM---------------------EQYA-----C--NLEEIVSERTAE--- 663

  Fly   803 KVNFNWRVDLRKEENAASLTNHSIIIILNNILPSHIVDVYLNSLAKHELYFENYRMVSVMFAMLI 867
                     |::|:..|.       .:|..:||..:..   ..:|...:..|.|..|::.|:.:.
Zfish   664 ---------LQEEKKRAE-------GLLTQMLPRSVAS---QLIAGKTVRAETYDCVTIYFSDIE 709

  Fly   868 NFEMDLRSL------RVLNEIIAEFDTLLLFYKEYYTVEKIKIVGCTYMAACGLDLNFAGSTSTN 926
            .|.....||      .|||::...||.::    :|:.|.|::.:|..||...||.:
Zfish   710 GFTAMSASLTPMQVVNVLNDLYTYFDNII----DYHNVYKVETIGDAYMVVSGLPI--------- 761

  Fly   927 RKESIPPTEFNEEQSRRILFQQSNEDLDEVVFVMTSYALDMMRTLAKSNEAYQSIAGDRNITDGT 991
                                 ::.:|..:.:..|:...:..:|:....:...|.:         .
Zfish   762 ---------------------RNGDDHAKEIARMSLAIVQGLRSFHSPHVPEQQL---------R 796

  Fly   992 IAIGISSGEVMAGIVGASQPHYDIWGNPVNMASRMESTGLPGHIHVTEETSEILQQF-GITCSYR 1055
            :.||:.||..:||:||...|.|.::|:.||.||||||.|||..|||:..|..:|..| ...|..|
Zfish   797 VRIGVHSGPCVAGVVGLKMPRYCLFGDTVNTASRMESYGLPLKIHVSSSTKSLLDTFRNFRCELR 861

  Fly  1056 GMTFVKGRGKIPTY-LVGID 1074
            |...:||:|.:.|: |:|.|
Zfish   862 GDIHIKGKGWVRTFWLLGED 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AC_N	<31..272	CDD:318454	48/248 (19%)
		Nucleotidyl_cyc_III	290..459	CDD:325147	37/189 (20%)
		Nucleotidyl_cyc_III	851..1071	CDD:325147	59/227 (26%)
si:dkey-37g12.1	XP_021333677.1	Periplasmic_Binding_Protein_Type_1	<59..258	CDD:324556	45/240 (19%)
		PKc_like	355..628	CDD:328722	64/344 (19%)
		HNOBA	<641..687	CDD:311573	15/95 (16%)
		CYCc	666..850	CDD:214485	56/236 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900