Protein Alignment ACXE and si:ch211-132f19.7

DIOPT Version :9

• Sequence 1: NP_652601.3
• Gene: ACXE / 53426
• FlyBaseID: FBgn0040506
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: XP_688903.4
• Gene: si:ch211-132f19.7 / 560410
• ZFINID: ZDB-GENE-130530-619
• Length: 1183
• Species: Danio rerio
• Alignment Length: 1144
• Identity: 321/1144 - (28%)
• Similarity: 522/1144 - (45%)
• Gaps: 227/1144 - (19%)

  Fly    71 ERRSIIYFDVALSIGCALVLI---LVLSVNFCDEFIAKHTW----YMYASSIFASLTLVFADLTE 128
            :||:.:.....:.|...|.:|   |.|:....|   ::|.|    .|...:|...|.|....|..
Zfish   150 QRRTSLVVTNVIDILTKLHIIFIYLALAPEMVD---SQHGWLAGLLMALGAIICVLVLTCKGLMS 211

  Fly   129 SIYHTYA--HSWI------LG----------TFYDTYIIYMIYMFLPIHFISGAVLLALLVSGLY 175
            ..|..||  .||:      ||          ::|..:.::.||..||:..: .::.:..|.:.|:
Zfish   212 PDYLRYAGLASWLSQTVQALGGLVYGLETDQSWYVLFTLFAIYTLLPLPLL-WSICMGFLTAALH 275

  Fly   176 ILYFVIFIAQGFAQFASALFSVGGMSVDIVHYLCLNLVGIFYRVMNDTVVRSSFLDRHQYIKEKI 240
             |:...|...........|.:.|      :.|:.:|..|:|...::|...|.:||:..:.|:.::
Zfish   276 -LFVDTFKNYNDTAIVRKLLAKG------LLYMGMNTAGLFIHYLSDRAQRQAFLETRRCIEGRV 333

  Fly   241 WLRNARLQEKQLLDSILPPQISLPLQKDIQGRIVMAKQGIHSWTAM-ERTMAIQIH-------PD 297
            .:.....::::|:.||||..|::.:..|:              ||: :..:..|.|       .|
Zfish   334 KMERENQRQERLVMSILPRFIAMEMIGDM--------------TALDDELLPQQFHKTYFHQYKD 384

  Fly   298 VSILYADVVNYTHLTTTLTVEMLVKVLHDLYGRFDLAAYRYKVQRIKFLGDCYYCVAGLSDPDPD 362
            ||||:||:..:|.|:.|:..:.||:.|::|:||||..|......|||.||||||||:|:.:|...
Zfish   385 VSILFADIKGFTSLSMTMPAQELVRTLNELFGRFDRLAEENHCMRIKILGDCYYCVSGVPEPQTA 449

  Fly   363 HANNCVILGLSMINHIMEVRDIHGLDINMRIGVHSGNLFAGVIGEAKLQFDIWGLDVTIANVLES 427
            ||..||.:||:|||.|..||.....|::||||:|||::..||:|..|.|||:|..||.:||:||:
Zfish   450 HARCCVEMGLAMINTIRYVRKELKRDMDMRIGIHSGSVLCGVLGLQKWQFDVWSWDVDVANMLEA 514

  Fly   428 TGVPGCVHISGATLNNLDVNRFDIEDGPEEARDHPLLKKYRIRSYIIRQDLHMDDE-------DS 485
            .|:||.:|||.|||:.|: ..::.|:|....|:. .|:|::|.:::||.....|.|       ..
Zfish   515 GGIPGRIHISRATLDCLE-GVYETEEGRGHERNE-FLRKHKIDTFLIRHTPQDDKEPPKVRRTSK 577

  Fly   486 DE-----------------FLGDLHSISLCNMGAQ--PRISDS--ANQSLRALFHEELREEFRKM 529
            ||                 .|....:.||.::..|  |..:.|  .|:.::........|..||.
Zfish   578 DETTWSAELPFDNIIGMNCILATFTNGSLVHLPNQITPHCAGSREINKRIKQAIEVRSSERMRKE 642

  Fly   530 PVSAFSPKRLLGICRFNTGKEVPAHQNLNICLTFTDPILERAYLKQTDYMYKYSIILSASVGCS- 593
            .::.|:                         |.|.|..:|..:.:..|.|:|      :::.||
Zfish   643 HITPFT-------------------------LVFKDTHIEGKFSQMRDEMFK------SNLACSF 676

  Fly   594 LVYIELMDTQMICSSCFVLPASVATIQCILALIAWYKKYCWT---RYGRNNVPHHYNGFSCFIFR 655
            |:.:.:|..|.:..|....|   ..||.::.|..:......|   .:.|:  |.:.....|:
Zfish   677 LLLLFIMAAQALIPSPQFFP---MIIQFLVFLFVYMLVLLVTLAEEFKRS--PPYLQHLCCW--- 733

  Fly   656 IHDKILNSLPIRICIYLFLMISSFFVMCLIVMSCQREEFEMAYIEERLFHYEQ-EAHICFHP--W 717
            ||:    :..||..:.|..:..:|.|....:..|.....|.....:...|.:| ..:||.||  :
Zfish   734 IHE----TKSIRNLLTLTAIAINFGVASCNIFWCNGTFEETEKSNKNSEHGKQWPVNICTHPEFF 794

  Fly   718 VTTNMLSLMICLTFTFAHIPIMVKTAV--AILETLAYLLLIFFQFDFVFHH---SVTTNPYFKSE 777
            |.:.:::::.|.  .|..:..::|.||  .::....||:.:.|...|:..|   .:..:.|.:.:
Zfish   795 VLSGVVAMVTCA--VFLRLSCLLKLAVLTLVIAVYTYLIEVAFHVLFIRQHQNSQIQRSQYLRRK 857

  Fly   778 YAHALLICITFLIMFVKERQIEFTNKVNFNWRVDLRKE-ENAASLTNHSIIIILNNILPSHIVDV 841
            ....||:.:..:::....||:|.|::::|.||:..|:| |:...|..|: ..:|.||||:|:...
Zfish   858 GISVLLMAMFVVVVLYNSRQLETTSRLDFLWRLQARQEVEDMKELREHN-ECLLYNILPAHVARH 921

  Fly   842 YLNSLAKHE-LYFENYRMVSVMFAMLINF----------EMDLRSLRVLNEIIAEFDTLLLFYKE 895
            :|.....:| |:.|:|..|.||||.:..|          ..|:..||:||||||:||.||  .:.
Zfish   922 FLERDRNNEDLFSESYERVGVMFASIPGFSDYYEKKELIHQDVECLRLLNEIIADFDELL--DEP 984

  Fly   896 YY-TVEKIKIVGCTYMAACGLDLNFAGSTSTNRKESIPPTEFNEEQSRRILFQQSNEDLDEVVFV 959
            |: .:||||.:|..||||.||        |..::|.                    ||....:..
Zfish   985 YFQDIEKIKTIGSCYMAASGL--------SPEKQEC--------------------EDEWAHLST 1021

  Fly   960 MTSYALDMMRTLAKSNEAYQSIAGDRNITDGTIAIGISSGEVMAGIVGASQPHYDIWGNPVNMAS 1024
            :..:||.|..||.:.|:        |...|..:.:|||.|.|:||::||::|.|||||..||:||
Zfish  1022 LVLFALAMQETLKEINK--------RTSNDFWLRVGISHGPVVAGVIGATKPQYDIWGMTVNLAS 1078

  Fly  1025 RMESTGLPGHIHVTEETSEILQQFGITCSYRGMTFVKG----RGKIPTYLVGIDENLNFIPQKAT 1085
            ||:||||.|.|.|.|.||.:|.:.|.....||..:|||    ||.:.||
Zfish  1079 RMDSTGLSGRIQVPEATSRVLAEHGFMLQLRGEIYVKGVSERRGAVRTY---------------- 1127

  Fly  1086 RFPSHQERSTVISLQSTYTHAENNNSIA-STSRHTLQSL 1123
             |.|.:|.::        ::||.|.|.. |..|:||.::
Zfish  1128 -FVSSREHNS--------SYAERNTSRGISLGRNTLAAV 1157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AC_N	<31..272	CDD:318454	49/225 (22%)
		Nucleotidyl_cyc_III	290..459	CDD:325147	80/175 (46%)
		Nucleotidyl_cyc_III	851..1071	CDD:325147	88/234 (38%)
si:ch211-132f19.7	XP_688903.4	AC_N	<133..375	CDD:292831	52/249 (21%)
		CYCc	338..537	CDD:214485	87/213 (41%)
		Guanylate_cyc	381..559	CDD:278633	82/179 (46%)
		DUF1053	579..667	CDD:283888	17/112 (15%)
		CYCc	903..1103	CDD:214485	87/238 (37%)
		Guanylate_cyc	932..1131	CDD:278633	89/253 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810