Protein Alignment ACXE and NPR3

DIOPT Version :9

• Sequence 1: NP_652601.3
• Gene: ACXE / 53426
• FlyBaseID: FBgn0040506
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: NP_001191304.1
• Gene: NPR3 / 4883
• HGNCID: 7945
• Length: 541
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 52/281 - (18%)
• Similarity: 90/281 - (32%)
• Gaps: 94/281 - (33%)

  Fly   295 HPDVSILYADVV---------NYTHLTTTLTV-----EMLVKVL-HDLYGRFDLAAYRYKVQRIK 344
            |.|:.:|.|..:         .|:|||.....     ||::.:. |..:.|..|.....|::|
Human   149 HWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLER-- 211

  Fly   345 FLGDCYYCVAGLSDPDPDHANNCVILGLSMINHIMEVRDIHGLDINMRIGVHSGNLFAGVIGEAK 409
               :||:.:.|:.:...:...:..|....      |.:|:...||...|......:......:
Human   212 ---NCYFTLEGVHEVFQEEGLHTSIYSFD------ETKDLDLEDIVRNIQASERVVIMCASSD-- 265

  Fly   410 LQFDIWGLDVTIANVLESTGVPGCVHISGATLNNLDVNRFDIE--------DGPEEARD------ 460
                      ||.:::.      ..|..|.|..  |...|:||        ||..:..|
Human   266 ----------TIRSIML------VAHRHGMTSG--DYAFFNIELFNSSSYGDGSWKRGDKHDFEA 312

  Fly   461 ----------------HPLLKKY--RIRSYIIRQDLHMDDEDSDEFLGDLHSISLCNMGAQPRIS 507
                            .|..:|:  .::|.:.:|.|:|:|. .:.|:...|...|..:.|
Human   313 KQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDY-VNMFVEGFHDAILLYVLA----- 371

  Fly   508 DSANQSLRALFHEELREEFRK 528
                      .||.||..:.|
Human   372 ----------LHEVLRAGYSK 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AC_N	<31..272	CDD:318454
		Nucleotidyl_cyc_III	290..459	CDD:325147	35/186 (19%)
		Nucleotidyl_cyc_III	851..1071	CDD:325147
NPR3	NP_001191304.1	PBP1_NPR_C_like	54..446	CDD:107381	52/281 (19%)
		ANF_receptor	71..422	CDD:279440	52/281 (19%)
		TM_EphA1	476..507	CDD:214014

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900