DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXE and Gyc89Db

DIOPT Version :9

Sequence 1:	NP_652601.3	Gene:	ACXE / 53426	FlyBaseID:	FBgn0040506	Length:	1123	Species:	Drosophila melanogaster
Sequence 2:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	72/298 - (24%)
Similarity:	127/298 - (42%)	Gaps:	80/298 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   785 CITFLIMFVKERQ----IEFTNKVNFNWRVDLRKEENAASLTNHSIIIILNNILPSHIVDVYLNS 845
            |....|||.||.|    :|.:.::..:|:   |:.:.           :|.:::|..|.:....|
  Fly   432 CSKLEIMFEKEEQRSDELEKSLELADSWK---RQGDE-----------LLYSMIPRPIAERMRKS 482

  Fly   846 LAKHELYFENYRMVSVMFAMLI--------NFEMDLRSLRVLNEIIAEFDTLLLFYKEYYTVEKI 902
               .|...:::..|||:|..::        |.:..::::..||::.:..|..::....|    |:
  Fly   483 ---EEHVCQSFEEVSVIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVY----KV 540

  Fly   903 KIVGCTYMAACGL-DLNFAGSTSTNRKESIPPTEFNEEQSRRILFQQSNEDLDEVVFVMTSYALD 966
            :.||..|||..|. |:|              |                         :...:|.|
  Fly   541 ETVGMVYMAVSGAPDVN--------------P-------------------------LHAEHACD 566

  Fly   967 MMRTLAKSNEAYQSIAGDRNITDGTIAIGISSGEVMAGIVGASQPHYDIWGNPVNMASRMESTGL 1031
            :...:.|..:|:.       :....|.:||:||.|:||:||...|.|.::|:.||.||||||:..
  Fly   567 LALRVMKKVKAHA-------LPGVAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSSD 624

  Fly  1032 PGHIHVTEETSEILQQFGITCSYRGMTFVKGRGKIPTY 1069
            |..|.::..|:..:|:.|.....||...|||:|::.||
  Fly   625 PWMIQLSNYTALKVQKVGYKVEARGFVKVKGKGEMETY 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AC_N	<31..272	CDD:318454
		Nucleotidyl_cyc_III	290..459	CDD:325147
		Nucleotidyl_cyc_III	851..1071	CDD:325147	57/228 (25%)
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	13/60 (22%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	57/225 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453994
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740