DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ACXE and Gyc88E

DIOPT Version :9

Sequence 1:	NP_652601.3	Gene:	ACXE / 53426	FlyBaseID:	FBgn0040506	Length:	1123	Species:	Drosophila melanogaster
Sequence 2:	NP_001036711.1	Gene:	Gyc88E / 41825	FlyBaseID:	FBgn0038295	Length:	1097	Species:	Drosophila melanogaster

Alignment Length:	328	Identity:	85/328 - (25%)
Similarity:	149/328 - (45%)	Gaps:	55/328 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 MIYM--FLPIHFISGAV---LLALLVSGLYILYFVIFIAQGFAQFASALFSVGGMSVDIVHYLCL 210
            |:||  :..|.|:...|   |.:|:.:||||                ...|:...|.|::
  Fly   307 MVYMENWRMIMFLGTPVMPDLTSLITTGLYI----------------NDLSMHDFSRDLM----- 350

  Fly   211 NLVGIFYRVMNDTVVRSSFLDRHQYIKEKIWLRNARLQEK-----QLLDSILPPQISLPLQKDIQ 270
             |.|     ...:|.....||:.|...:|:......|.|:     :||..::|.|::
  Fly   351 -LAG-----TQQSVELKLALDQEQQKSKKLEESMRLLDEEMRRTDELLYQMIPKQVA-------- 401

  Fly   271 GRIVMAKQGIHSWTAMERTMAIQIHPDVSILYADVVNYTHLTTTLTVEMLVKVLHDLYGRFDLAA 335
            .|:...:..|.:         .::...||||::|:|.:|.:.:.:|...:|.:|:.:|..||...
  Fly   402 DRLRRGENPIDT---------CEMFDSVSILFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLT 457

  Fly   336 YRYKVQRIKFLGDCYYCVAGLSDPDPDHANNCVILGLSMINHIMEVRD-IHGLDINMRIGVHSGN 399
            .|..|.:::.:||.|..|||..|.|.:||.....:.|.|::.|.:::| ..|..:.:|:|||||.
  Fly   458 ERNSVYKVETIGDAYMVVAGAPDKDANHAERVCDMALDMVDAITDLKDPSTGQHLRIRVGVHSGA 522

  Fly   400 LFAGVIGEAKLQFDIWGLDVTIANVLESTGVPGCVHISGATLNNLDVNRFDIEDGPEEARDHPLL 464
            :.||::|....::.::|..|..|:.:|||.:...||||.:|...:..|...||.|..:.:....:
  Fly   523 VVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLIGPNYKIIERGEIDVKGKGTM 587

  Fly   465 KKY 467
            ..|
  Fly   588 GTY 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AC_N	<31..272	CDD:318454	28/130 (22%)
		Nucleotidyl_cyc_III	290..459	CDD:325147	54/169 (32%)
		Nucleotidyl_cyc_III	851..1071	CDD:325147
Gyc88E	NP_001036711.1	HNOB	2..164	CDD:311572
		HNOBA	201..404	CDD:311573	28/131 (21%)
		CYCc	383..571	CDD:214485	57/204 (28%)
		Herpes_ICP4_C	794..>955	CDD:332854
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453996
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740