Protein Alignment ACXE and CG10738

DIOPT Version :9

• Sequence 1: NP_652601.3
• Gene: ACXE / 53426
• FlyBaseID: FBgn0040506
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Alignment Length: 1179
• Identity: 232/1179 - (19%)
• Similarity: 404/1179 - (34%)
• Gaps: 357/1179 - (30%)

  Fly    89 VLILVLSVN-------FCDEFIAKHTWYMYASSIFASLTLVFADLTE-----SIYHTYAHSWILG 141
            |:.|:|:.|       :.|:  |...:...|.:|.::||.....:.:     :|||   |.::..
  Fly   171 VVALLLAFNWTQVSFLYLDD--ASGQYQPVAETILSTLTDAGVSIRDIRTWNTIYH---HGFMDN 230

  Fly   142 TF----YDTYIIYMIYMFLPIHFISGAVLLALLVSGLYIL--YFVIFI----------------- 183
            .|    ..||....||:.|..::....::::|...|:...  |||:.|
  Fly   231 PFEALVEQTYANTRIYLILGHYYEHVGLMVSLQRRGILSKGDYFVVGIDIEQYDPAKPEKYLRGL 295

  Fly   184 ---------AQGFAQF----ASALFSVGGMSVDIVHYL------CLNLVGIFYRVMNDTVVRSSF 229
                     .|.|..:    .:|..|....:.::..|:      ..|.:|.|..|...:...:..
  Fly   296 LLEDVEPLAVQAFQSYLGIVPTASVSFATFANEVNKYMERPPFNFPNPLGPFGGVKQISAEAAYL 360

  Fly   230 LDR-HQYIKEKIWLRNARLQEKQLLDSILPPQISLPLQKDIQGRIVMAKQGIH-----------S 282
            .|. |.|.|..:          ::|||...|:....:...|:|....:..|.|           :
  Fly   361 YDAVHLYAKALM----------EVLDSGGRPRNGSAIVAAIKGSRYRSAMGYHVYIDENGDAAGN 415

  Fly   283 WTAMERTMAIQIHPDVSILYADVVNYTHLTTTLTVEMLVKVL-HDLYGRFDLAAYRYKVQRIKFL 346
            :|.:.|...........:....|..:.|..::|:  .:.|.| |               |.:|..
  Fly   416 YTVLARGSVRNGRNQTVLGLRPVGTFIHRNSSLS--SISKALPH---------------QNLKLF 463

  Fly   347 GDCYYCVAGLSDPDPDHANNCVILGLSMINHIMEVRDIHGLDINMRIGVHSGNLFAGVIGEAKLQ 411
            ....: |.|..   |..|..|...|...:|:..|:.........:.:.:.|..|:.....|.:|.
  Fly   464 SPIDW-VGGTR---PAAAPRCGFGGEKCVNYTGEISAAIAGGALLLLSLVSLVLYRNWRYEQELD 524

  Fly   412 FDIWGLDVTIANVLESTGVPGCVHISGATLNNLDVNRFDIEDGPEEARDHPLLKKYRIRSYIIRQ 476
            ..:|.:|.....:.|:.........:...||:|. .|.     |.:: .|||::..::..
  Fly   525 SLLWKIDFREVQIHENEREQQSQKQTRHLLNHLP-RRL-----PPQS-THPLIRTSQVSL----- 577

  Fly   477 DLHMDDEDSD-----------EFLGDLHSISLCNMGAQPRISDSANQSLRALFHEELREEFRKMP 530
               ..:.|:|           .:.|.|::|.    ..:.:..|...:..:.|   :|..:.|...
  Fly   578 ---SSNPDADFRYTTIFTPIGLYKGQLYAIK----KVRKKSVDITREMKKEL---KLLRDARHDN 632

  Fly   531 VSAFSPKRLLGICRFNTGKEVPAHQNLNICL--------TFTDPILERAYLKQTDYMYKYSIILS 587
            :.||     :|.|     .:.|     |||:        :..| |||...:| .|.|:..|::
  Fly   633 ICAF-----IGAC-----TDPP-----NICIISEYCTRGSLKD-ILENEDVK-LDNMFIASMV-- 678

  Fly   588 ASVGCSLVYIELMDTQMICSSCFVLPASVATIQCILALIAWYKKYCWTRYGRNNVPHHYNGFSCF 652
            |.:...::|:.        .|......::.|..|::. ..|..|              ...|..|
  Fly   679 ADIIRGVIYLH--------DSPIRFHGALCTSNCLVD-SRWVVK--------------LTDFGLF 720

  Fly   653 IFR--IHDKILNSLPIRI-CIYLFLMISSFFVM--CLIVMSCQREEFEMAYIEERLFHYEQEAHI 712
            .|:  |.|...:...:.. |:.|..........  ..:||..||.:   ||....|.:   |.|:
  Fly   721 AFKQGIEDSSTDMQHMSAKCLKLLYRAPELLRQGPSSLVMGTQRGD---AYSFGILLY---EMHV 779

  Fly   713 CFHPWVTTNMLSLMICLTFTFAHIPIMVKTAVAILETLAYLLLIFFQFDFVFHHSVTTNPYFKS- 776
            ...|:..|. |:.|.||.              .:|:...||                 |||..|
  Fly   780 RRGPFGETG-LTPMQCLQ--------------KVLQPQDYL-----------------NPYRPSL 812

  Fly   777 EYAHALLICIT----------------FLIMFVKERQIE-------FTNKV--------NFNWRV 810
            :.......|::                |..:..|.|.:.       |.|.:        |....|
  Fly   813 QPLETAFDCVSECLRECWAERPEDRPDFKTIRTKLRPLRKGMRPNIFDNMMAMMEKYANNLEALV 877

  Fly   811 D-----LRKEENAASLTNHSIIIILNNILPSHIVDVYLNSLAK-HELYFENYRMVSVMFAMLINF 869
            |     |::|:....       .:|:.:||..:.|    .|.| |::..|:|..||:.|:.::.|
  Fly   878 DDRTDQLQEEKKKTD-------ALLHEMLPRCVAD----QLKKGHKVDPEHYEQVSIYFSDIVGF 931

  Fly   870 E------MDLRSLRVLNEIIAEFDTLLLFYKEYYTVEKIKIVGCTYMAACGL-----DLNFA--G 921
            .      ..|:.:..||::...||:::    .:|.|.|::.:|..||...||     ||:.|  .
  Fly   932 TAMSAECTPLQVVDFLNDLYTCFDSII----GHYDVYKVETIGDAYMVVSGLPLRNGDLHAAEIA 992

  Fly   922 STSTNRKESIPPTEFNEEQSRRILFQQSNEDLDEVVFVMTSYALDMMRTLAKSNEAYQSIAGDRN 986
            :.|.:...::...:.....:.|:|
  Fly   993 TMSLHLLSAVSEFKIRHRPTNRLL----------------------------------------- 1016

  Fly   987 ITDGTIAIGISSGEVMAGIVGASQPHYDIWGNPVNMASRMESTGLPGHIHVTEETSEILQQFGIT 1051
                 :.|||.||.|.||:||...|.|.::|:.||.||||||:|:|..||.:.:..::|.:.|
  Fly  1017 -----LRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLG-- 1074

  Fly  1052 CSY----RGMTFVKGRGKIPTY-LVGIDENLNFIPQKATRFPSHQERSTVIS--LQSTYTHAE-- 1107
             .|    ||:..:||:|...|| |:|.||...   .:.|...|.:..|..::  :|.|...|:
  Fly  1075 -GYHFAERGVISMKGKGDQRTYWLLGEDEEAR---TRRTYERSQRRGSRALNKFIQGTIKQAQEQ 1135

  Fly  1108 -NNNSIAST 1115
             |...|.|:
  Fly  1136 ANEYGIRSS 1144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AC_N	<31..272	CDD:318454	44/237 (19%)
		Nucleotidyl_cyc_III	290..459	CDD:325147	28/169 (17%)
		Nucleotidyl_cyc_III	851..1071	CDD:325147	60/237 (25%)
CG10738	NP_729905.2	PBP1_Speract_GC_like	41..441	CDD:107365	50/284 (18%)
		ANF_receptor	67..416	CDD:279440	47/259 (18%)
		PK_GC-A_B	570..853	CDD:270944	65/377 (17%)
		TyrKc	597..847	CDD:197581	61/336 (18%)
		HNOBA	<862..907	CDD:285003	9/55 (16%)
		CYCc	886..1078	CDD:214485	61/255 (24%)
		Guanylate_cyc	913..1099	CDD:278633	61/238 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900