Protein Alignment ACXE and GUCY1B1

DIOPT Version :9

• Sequence 1: NP_652601.3
• Gene: ACXE / 53426
• FlyBaseID: FBgn0040506
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: XP_011530203.1
• Gene: GUCY1B1 / 2983
• HGNCID: 4687
• Length: 662
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 75/275 - (27%)
• Similarity: 117/275 - (42%)
• Gaps: 71/275 - (25%)

  Fly   811 DLRKEENAASLTNHSIIII-LNNILPSHIVDVYLNSLA-KHELYFENYRMVSVMFAMLINF---- 869
            |.|..:...|::....::| ||.:|.|.:.....|.|. |..:..:.|..|:::|:.::.|
Human   413 DSRSTKGFPSISYSGFLLIPLNRLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFC 477

  Fly   870 ------EMDLRSLRVLNEIIAEFDTLLLFYKEYYTVEKIKIVGCTYMAACGLDLNFAGSTSTNRK 928
                  |..::.:.:||::...||||....|..: |.|::.||..||...||
Human   478 SKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPF-VYKVETVGDKYMTVSGL------------- 528

  Fly   929 ESIPPTEFNEEQSRRILFQQSNEDLDEVVFVMTSYALDMMRTLAKSNEAYQSIAGDRNITDG--- 990
               |....:..:|                  :...|||||           .|||...: ||
Human   529 ---PEPCIHHARS------------------ICHLALDMM-----------EIAGQVQV-DGESV 560

  Fly   991 TIAIGISSGEVMAGIVGASQPHYDIWGNPVNMASRMESTGLPGHIHVTEETSEILQ-------QF 1048
            .|.|||.:|||:.|::|...|.|.::||.||:.||.|:||..|.|:|:|.|...|.       ||
Human   561 QITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQF 625

  Fly  1049 GITCSYRGMTFVKGR 1063
            .:  .:||...:||:
Human   626 HL--EHRGPVSMKGK 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AC_N	<31..272	CDD:318454
		Nucleotidyl_cyc_III	290..459	CDD:325147
		Nucleotidyl_cyc_III	851..1071	CDD:325147	64/233 (27%)
GUCY1B1	XP_011530203.1	HNOB	2..166	CDD:311572
		HNOBA	207..449	CDD:311573	9/35 (26%)
		Guanylate_cyc	455..648	CDD:306677	64/233 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810