Protein Alignment ACXE and Gucy1b2

DIOPT Version :9

• Sequence 1: NP_652601.3
• Gene: ACXE / 53426
• FlyBaseID: FBgn0040506
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: NP_001257640.1
• Gene: Gucy1b2 / 25206
• RGDID: 2770
• Length: 742
• Species: Rattus norvegicus
• Alignment Length: 484
• Identity: 104/484 - (21%)
• Similarity: 180/484 - (37%)
• Gaps: 163/484 - (33%)

  Fly   691 REEFEMAY-----IEERLFHYEQEAHICF----------------------------------HP 716
            |:.|:..|     :||.:|......||.|                                  ||
  Rat   251 RDTFQPVYPERLWVEEEVFCDAFPFHIVFDEALRVKQAGVNIQKYVPGILTQKFALDEYFSIIHP 315

  Fly   717 WVTTNMLSLMICLTFTFAHIPIMVKTAVAI-------------------LETLAYLLLIF----- 757
            .||.|:.|  ||   .|.:...::||...:                   :|:|..::.:.
  Rat   316 QVTFNISS--IC---KFINSQFVLKTRKEMMPKARKSQPMLKLRGQMIWMESLRCMIFMCSPKLR 375

  Fly   758 ---------FQFDFVFHHSVTTNPYFKSEYAHALLICITFLIMFVKERQIEFTNKVNFNWRVDLR 813
                     .....:..|..|.:                 ||:..::|..|    :..:.:::.:
  Rat   376 SLQELEESKMHLSDIAPHDTTRD-----------------LILLNQQRLAE----MELSCQLEKK 419

  Fly   814 KEENAASLTNHSII------IILNNILPSHIVDVYLNSLAK-HELYFENYRMVSVMFAMLINFE- 870
            ||| ...|:||..|      .:|..:||.|:.    |.|.: .::....:...:::|:.::.|.
  Rat   420 KEE-LRVLSNHLAIEKKKTETLLYAMLPEHVA----NQLKEGRKVAAGEFETCTILFSDVVTFTN 479

  Fly   871 -----MDLRSLRVLNEIIAEFDTLLLFYKEYYTVEKIKIVGCTYMAACGLDLNFAGSTSTNRKES 930
                 ..::.:.:||.:.::||.|...:..|    |::.:|..||...|:.:
  Rat   480 ICAACEPIQIVNMLNSMYSKFDRLTSVHDVY----KVETIGDAYMVVGGVPV------------- 527

  Fly   931 IPPTEFNEEQSRRILFQQSNEDLDEVVFVMTSYALDMMRTLAKSNEAYQSIAGDRNITDGTIAIG 995
              |.|.:.::                   :.::||. ||..||  |....:.|:    ...|.:|
  Rat   528 --PVESHAQR-------------------VANFALG-MRISAK--EVMNPVTGE----PIQIRVG 564

  Fly   996 ISSGEVMAGIVGASQPHYDIWGNPVNMASRMESTGLPGHIHVTEETSEILQQFGITCSYRGMTFV 1060
            |.:|.|:||:||...|.|.::|:.||.||||||.|||..:|::......|:..|.....||...|
  Rat   565 IHTGPVLAGVVGDKMPRYCLFGDTVNTASRMESHGLPSKVHLSPTAHRALKNKGFEIVRRGEIEV 629

  Fly  1061 KGRGKIPTYLVGIDENLNFIPQKATRFPS 1089
            ||:||:.||.  :.:|||....:....||
  Rat   630 KGKGKMTTYF--LIQNLNATEDEIMGRPS 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AC_N	<31..272	CDD:318454
		Nucleotidyl_cyc_III	290..459	CDD:325147
		Nucleotidyl_cyc_III	851..1071	CDD:325147	58/225 (26%)
Gucy1b2	NP_001257640.1	HNOB	2..163	CDD:285002
		HNOBA	267..453	CDD:285003	35/216 (16%)
		CYCc	432..622	CDD:214485	56/238 (24%)
		Guanylate_cyc	459..642	CDD:278633	58/229 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810