Protein Alignment ACXE and LOC1272957

DIOPT Version :10

• Sequence 1: NP_652601.3
• Gene: ACXE / 53426
• FlyBaseID: FBgn0040506
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: XP_061519369.1
• Gene: LOC1272957 / 1272957
• VectorBaseID: AGAMI1_006876
• Length: 1413
• Species: Anopheles gambiae
• Alignment Length: 1063
• Identity: 314/1063 - (29%)
• Similarity: 502/1063 - (47%)
• Gaps: 178/1063 - (16%)

  Fly    43 LWKSYLLTFFMLHIFVTSVHCALLLATIERR--SIIYFDVALSIGCALVLILVLSVNFCDEFIAK 105
            |.|..:....:|.:..| |:..||:...::|  .|..|.|:..|   :|.:|||.|.|.....||
Mosquito   486 LLKDNMTQIIVLGVCAT-VYALLLMCLYKQRINEIYLFQVSYVI---MVTLLVLDVCFSFTTSAK 546

  Fly   106 HTWYMYASSIFASLTLVFADLTESIYHTYAHSWILGTFYDTYIIYMIYMFLPIHF---ISGAVLL 167
                .:.||  ...|::                         .||:||..|||..   :.|..||
Mosquito   547 ----KFTSS--GGCTVI-------------------------AIYIIYTMLPIRLREAVVGGSLL 580

  Fly   168 ALLVSGLYILYFVIFIAQGFAQFASALFSVGGMSVDIVHYLCLNLVGIFYRVMNDTVVRSSFLDR 232
            :  :|.:.:::::           :....:..:..|::...|.|..||......:...|.:|::.
Mosquito   581 S--ISHIALMFYM-----------NESDDMDVLYCDLITLACTNATGILLHWPKEKSQRKAFMET 632

  Fly   233 HQYIKEKIWLRNARLQEKQLLDSILPPQISLPLQKDIQGRIVMAKQGIHSWTAMERTMAIQIHPD 297
            .|.::.::.::....:::|||.|:||..:::.::.||.|:...|:  .|.       :.||.|.:
Mosquito   633 RQCVEARLKIQRENQKQEQLLLSVLPRHVAMEMKNDIAGQPREAQ--FHK-------IYIQRHEN 688

  Fly   298 VSILYADVVNYTHLTTTLTVEMLVKVLHDLYGRFDLAAYRYKVQRIKFLGDCYYCVAGLSDPDPD 362
            ||||:||:..:|.|:...|.|.||::|::|:.|||..|..:...|||.||||||||:||.:..||
Mosquito   689 VSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAQEHHCLRIKLLGDCYYCVSGLPEARPD 753

  Fly   363 HANNCVILGLSMINHIMEVRDIHGLDINMRIGVHSGNLFAGVIGEAKLQFDIWGLDVTIANVLES 427
            ||...|.:||.||:.|..||::..:::|||:|:|:|.:..||:|..|.|||:|..|||:||.:||
Mosquito   754 HALCAVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCGVLGLRKWQFDVWSNDVTLANYMES 818

  Fly   428 TGVPGCVHISGATLNNLDVNRFDIEDGPEEARDHPLLKKYRIRSY-IIRQDL----HMDDEDSDE 487
            .||||.|||:..||..|. :.:|:|:| ..|..:..||.::|::| |:.:|.    |...:.|..
Mosquito   819 GGVPGRVHITKETLRCLG-DHYDVEEG-RGADRNSYLKDHQIQTYLIVPKDASYRPHTMSKQSSS 881

  Fly   488 FLGDLHSISLCNMGAQPRISDSANQSLRALFHEELREEFRKMPVSAFSPKRL-LGIC-RFNTGKE 550
            ..|:: |..|..||...::  ..|........||...|:....:.|.|..|| |..| ||:
Mosquito   882 VNGNI-SKELRMMGHWSKM--GFNDKTEPKSTEEEVNEYLIKAIDARSIDRLRLDHCKRFH---- 939

  Fly   551 VPAHQNLNICLTFTDPILERAYLKQTDYMYKYSIILSASVGCS-LVYIELMDTQMICSSCFVLPA 614
                      |||....:||.|..:.|.|      |:....|| ::::.:|..|::..|......
Mosquito   940 ----------LTFIKDEIERKYCLEPDPM------LNVYFYCSIIIFLGIMSIQVLVFSMDHYSY 988

  Fly   615 SVATIQCILALIAWYKKYCWTRYGRNNVPHHYNGFSCFIFRIHDKILN----SLPIRICIYLFLM 675
            .|..|..:..|::     |...:.|.::.     .|.|...:..||..    :..|.:|:.:.::
Mosquito   989 WVYGILSLTLLVS-----CVPVFTREDMK-----VSTFFRALSQKIHGHREIAQVISLCVVITVI 1043

  Fly   676 ISSFFVMCLIVMSCQREEFEMAYIEERLFHYEQEAHICFHPWVTTNMLSLMICLTFTFAHIPIMV 740
            ..|::.:.||......:||.:......     :|:.| .:..:...:|:|:.|....|  |.|:.
Mosquito  1044 CLSYYKLTLIFYLSLYDEFPLVRPSNC-----KESKI-INILLLLTLLALLTCAVHQF--IKILF 1100

  Fly   741 KTAVAILETLAYLL-LIFFQFDFVFHHSVTTNPYFKSEYAHALLICITFLIMFV-----KERQIE 799
            |..:.|:..:.|:. :|.....|..|    ..|:|.:  ....||.:.||::||     ..:|.|
Mosquito  1101 KILLLIVILVLYIASIIVLALIFERH----CEPWFLT--TERFLIDVAFLVVFVIGQIMHSQQTE 1159

  Fly   800 FTNKVNFNWRVDLRKEENAASLTNHSIIIILNNILPSHIVDVYL-NSLAKHELYFENYRMVSVMF 863
            .|.:::|.|::...:|:............:|.||||.|:.|.:| ......|:|.|....|.|||
Mosquito  1160 ITRRLDFIWKLQATEEKEDMEHLQAYNRKLLANILPVHVADHFLMREKNIEEIYHEQCDTVCVMF 1224

  Fly   864 AMLINF-----EMD-----LRSLRVLNEIIAEFDTLLLFYKEYYTVEKIKIVGCTYMAACGLDLN 918
            |.:.||     |::     :..||:|||||.:||.||...:..| |||||..|.|||||.||..|
Mosquito  1225 ASIPNFSEFYIELEGNNEGVECLRLLNEIIVDFDELLGLERFRY-VEKIKTTGSTYMAASGLTAN 1288

  Fly   919 FAGSTSTNRKESIPPTEFNEEQSRRILFQQSNEDLDEVVFVMTSYALDMMRTLAKSNEAYQSIAG 983
                 |.::.:                ||.        ||.|..|||::.:.:...||
Mosquito  1289 -----SCDKND----------------FQH--------VFAMMDYALELFQKITDVNE------- 1317

  Fly   984 DRNITDGTIAIGISSGEVMAGIVGASQPHYDIWGNPVNMASRMESTGLPGHIHVTEETSEILQQF 1048
             .:..:..:.|||:.|.|:||::|..:|.||||||.||:||||:||||..||.|||:..:|::..
Mosquito  1318 -HSFNNFRMRIGINIGPVVAGVIGTRKPQYDIWGNAVNVASRMDSTGLMDHIQVTEDVYQIVKDK 1381

  Fly  1049 GITCSYRGMTFVKGRGKIPTYLV 1071
            |...:.||...|||:|.:.|||:
Mosquito  1382 GYNLTCRGTVNVKGKGTMITYLM 1404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AcyC	65..453	CDD:441717	126/392 (32%)
		Nucleotidyl_cyc_III	290..459	CDD:448371	80/168 (48%)
		Nucleotidyl_cyc_III	851..1071	CDD:448371	87/229 (38%)
LOC1272957	XP_061519369.1	None